| Full name: dihydrouridine synthase 1 like | Alias Symbol: PP3111|DUS1 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 64118 | HGNC ID: HGNC:30086 | Ensembl Gene: ENSG00000169718 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DUS1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUS1L | 64118 | 217912_at | 0.6565 | 0.2806 | |
| GSE20347 | DUS1L | 64118 | 217912_at | 0.1963 | 0.1722 | |
| GSE23400 | DUS1L | 64118 | 217912_at | 0.3729 | 0.0000 | |
| GSE26886 | DUS1L | 64118 | 217912_at | 0.7582 | 0.0000 | |
| GSE29001 | DUS1L | 64118 | 217912_at | 0.0764 | 0.8049 | |
| GSE38129 | DUS1L | 64118 | 217912_at | 0.4447 | 0.0018 | |
| GSE45670 | DUS1L | 64118 | 217912_at | 0.1772 | 0.2722 | |
| GSE53622 | DUS1L | 64118 | 45173 | 0.1159 | 0.1500 | |
| GSE53624 | DUS1L | 64118 | 4410 | 0.2748 | 0.0000 | |
| GSE63941 | DUS1L | 64118 | 217912_at | 0.4620 | 0.1600 | |
| GSE77861 | DUS1L | 64118 | 217912_at | 0.2064 | 0.2723 | |
| GSE97050 | DUS1L | 64118 | A_23_P255569 | 0.5412 | 0.1413 | |
| SRP007169 | DUS1L | 64118 | RNAseq | -0.4785 | 0.1456 | |
| SRP008496 | DUS1L | 64118 | RNAseq | -0.2009 | 0.4069 | |
| SRP064894 | DUS1L | 64118 | RNAseq | 0.4370 | 0.0564 | |
| SRP133303 | DUS1L | 64118 | RNAseq | 0.2675 | 0.0541 | |
| SRP159526 | DUS1L | 64118 | RNAseq | 0.4352 | 0.0489 | |
| SRP193095 | DUS1L | 64118 | RNAseq | -0.0652 | 0.4425 | |
| SRP219564 | DUS1L | 64118 | RNAseq | 0.1025 | 0.7531 | |
| TCGA | DUS1L | 64118 | RNAseq | 0.0021 | 0.9672 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DUS1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUS1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUS1L | 64118 | 4 | 4 | 22 | |
| GSE20123 | DUS1L | 64118 | 4 | 4 | 22 | |
| GSE43470 | DUS1L | 64118 | 3 | 5 | 35 | |
| GSE46452 | DUS1L | 64118 | 34 | 0 | 25 | |
| GSE47630 | DUS1L | 64118 | 9 | 2 | 29 | |
| GSE54993 | DUS1L | 64118 | 2 | 5 | 63 | |
| GSE54994 | DUS1L | 64118 | 10 | 6 | 37 | |
| GSE60625 | DUS1L | 64118 | 6 | 0 | 5 | |
| GSE74703 | DUS1L | 64118 | 3 | 3 | 30 | |
| GSE74704 | DUS1L | 64118 | 4 | 3 | 13 | |
| TCGA | DUS1L | 64118 | 24 | 13 | 59 |
Total number of gains: 103; Total number of losses: 45; Total Number of normals: 340.
Somatic mutations of DUS1L:
Generating mutation plots.
Highly correlated genes for DUS1L:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUS1L | MRPL12 | 0.746973 | 8 | 0 | 8 |
| DUS1L | TMEM102 | 0.701955 | 3 | 0 | 3 |
| DUS1L | GSK3A | 0.697801 | 3 | 0 | 3 |
| DUS1L | HGS | 0.691271 | 7 | 0 | 6 |
| DUS1L | NACC1 | 0.680315 | 4 | 0 | 3 |
| DUS1L | PRKCZ | 0.680269 | 4 | 0 | 3 |
| DUS1L | ATAD3B | 0.675329 | 5 | 0 | 4 |
| DUS1L | UNC93B1 | 0.667471 | 6 | 0 | 4 |
| DUS1L | SYT7 | 0.665226 | 3 | 0 | 3 |
| DUS1L | ECSIT | 0.662368 | 4 | 0 | 4 |
| DUS1L | SNX10 | 0.662186 | 3 | 0 | 3 |
| DUS1L | SURF6 | 0.660092 | 3 | 0 | 3 |
| DUS1L | C21orf58 | 0.656798 | 3 | 0 | 3 |
| DUS1L | CDCP1 | 0.646887 | 3 | 0 | 3 |
| DUS1L | NOP14 | 0.644612 | 8 | 0 | 7 |
| DUS1L | GEMIN4 | 0.641663 | 7 | 0 | 6 |
| DUS1L | ANAPC5 | 0.641325 | 6 | 0 | 6 |
| DUS1L | CHCHD6 | 0.638877 | 3 | 0 | 3 |
| DUS1L | WDTC1 | 0.634935 | 3 | 0 | 3 |
| DUS1L | F11R | 0.634497 | 7 | 0 | 5 |
For details and further investigation, click here
