| Full name: NOC2 like nucleolar associated transcriptional repressor | Alias Symbol: DKFZP564C186|NET7|NET15|NIR|PPP1R112 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 26155 | HGNC ID: HGNC:24517 | Ensembl Gene: ENSG00000188976 | OMIM ID: 610770 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NOC2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOC2L | 26155 | 202115_s_at | 0.2902 | 0.3765 | |
| GSE20347 | NOC2L | 26155 | 202115_s_at | 0.2534 | 0.0650 | |
| GSE23400 | NOC2L | 26155 | 202115_s_at | 0.2676 | 0.0005 | |
| GSE26886 | NOC2L | 26155 | 202115_s_at | -0.0179 | 0.9253 | |
| GSE29001 | NOC2L | 26155 | 202115_s_at | 0.1512 | 0.5466 | |
| GSE38129 | NOC2L | 26155 | 202115_s_at | 0.3581 | 0.0025 | |
| GSE45670 | NOC2L | 26155 | 202115_s_at | 0.2893 | 0.0570 | |
| GSE63941 | NOC2L | 26155 | 202115_s_at | 0.7122 | 0.0271 | |
| GSE77861 | NOC2L | 26155 | 202115_s_at | -0.0219 | 0.9214 | |
| GSE97050 | NOC2L | 26155 | A_23_P336015 | 0.2785 | 0.3091 | |
| SRP007169 | NOC2L | 26155 | RNAseq | 0.0226 | 0.9663 | |
| SRP008496 | NOC2L | 26155 | RNAseq | -0.1179 | 0.7068 | |
| SRP064894 | NOC2L | 26155 | RNAseq | 0.6588 | 0.0014 | |
| SRP133303 | NOC2L | 26155 | RNAseq | 0.6021 | 0.0078 | |
| SRP159526 | NOC2L | 26155 | RNAseq | 0.3421 | 0.3404 | |
| SRP193095 | NOC2L | 26155 | RNAseq | 0.3999 | 0.0021 | |
| SRP219564 | NOC2L | 26155 | RNAseq | 0.2870 | 0.3162 | |
| TCGA | NOC2L | 26155 | RNAseq | 0.1922 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOC2L expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NOC2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOC2L | 26155 | 3 | 7 | 20 | |
| GSE20123 | NOC2L | 26155 | 3 | 6 | 21 | |
| GSE43470 | NOC2L | 26155 | 1 | 5 | 37 | |
| GSE46452 | NOC2L | 26155 | 7 | 1 | 51 | |
| GSE47630 | NOC2L | 26155 | 8 | 4 | 28 | |
| GSE54993 | NOC2L | 26155 | 2 | 2 | 66 | |
| GSE54994 | NOC2L | 26155 | 15 | 2 | 36 | |
| GSE60625 | NOC2L | 26155 | 0 | 0 | 11 | |
| GSE74703 | NOC2L | 26155 | 1 | 3 | 32 | |
| GSE74704 | NOC2L | 26155 | 3 | 0 | 17 | |
| TCGA | NOC2L | 26155 | 14 | 20 | 62 |
Total number of gains: 57; Total number of losses: 50; Total Number of normals: 381.
Somatic mutations of NOC2L:
Generating mutation plots.
Highly correlated genes for NOC2L:
Showing top 20/594 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOC2L | HIC2 | 0.834829 | 3 | 0 | 3 |
| NOC2L | DHX37 | 0.773901 | 4 | 0 | 4 |
| NOC2L | GPBP1L1 | 0.772964 | 4 | 0 | 4 |
| NOC2L | PPP1R37 | 0.771308 | 3 | 0 | 3 |
| NOC2L | TGIF2 | 0.769245 | 3 | 0 | 3 |
| NOC2L | COMMD5 | 0.762458 | 3 | 0 | 3 |
| NOC2L | B9D2 | 0.759882 | 3 | 0 | 3 |
| NOC2L | PI4K2A | 0.759248 | 3 | 0 | 3 |
| NOC2L | ELOF1 | 0.755067 | 5 | 0 | 5 |
| NOC2L | CCNJ | 0.75304 | 3 | 0 | 3 |
| NOC2L | COQ4 | 0.748035 | 3 | 0 | 3 |
| NOC2L | USP1 | 0.737903 | 3 | 0 | 3 |
| NOC2L | DHX33 | 0.735394 | 3 | 0 | 3 |
| NOC2L | SPHK2 | 0.73178 | 3 | 0 | 3 |
| NOC2L | MRPL52 | 0.730036 | 3 | 0 | 3 |
| NOC2L | AURKAIP1 | 0.728158 | 9 | 0 | 8 |
| NOC2L | NAF1 | 0.726242 | 3 | 0 | 3 |
| NOC2L | MRPL37 | 0.724759 | 5 | 0 | 5 |
| NOC2L | GPR158 | 0.721324 | 3 | 0 | 3 |
| NOC2L | GSK3B | 0.72003 | 3 | 0 | 3 |
For details and further investigation, click here
