| Full name: ribosome binding protein 1 | Alias Symbol: ES/130|hES | ||
| Type: protein-coding gene | Cytoband: 20p12.1 | ||
| Entrez ID: 6238 | HGNC ID: HGNC:10448 | Ensembl Gene: ENSG00000125844 | OMIM ID: 601418 |
| Drug and gene relationship at DGIdb | |||
Expression of RRBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RRBP1 | 6238 | 201204_s_at | 0.6959 | 0.1966 | |
| GSE20347 | RRBP1 | 6238 | 201204_s_at | -0.2471 | 0.1980 | |
| GSE23400 | RRBP1 | 6238 | 201204_s_at | 0.1984 | 0.0172 | |
| GSE26886 | RRBP1 | 6238 | 201204_s_at | 0.5067 | 0.0478 | |
| GSE29001 | RRBP1 | 6238 | 201204_s_at | -0.0659 | 0.7871 | |
| GSE38129 | RRBP1 | 6238 | 201204_s_at | -0.0525 | 0.8525 | |
| GSE45670 | RRBP1 | 6238 | 201204_s_at | 0.6250 | 0.0000 | |
| GSE53622 | RRBP1 | 6238 | 78900 | 0.1216 | 0.1121 | |
| GSE53624 | RRBP1 | 6238 | 78900 | 0.2274 | 0.0023 | |
| GSE63941 | RRBP1 | 6238 | 201204_s_at | -1.9740 | 0.0036 | |
| GSE77861 | RRBP1 | 6238 | 201204_s_at | 0.2255 | 0.4816 | |
| GSE97050 | RRBP1 | 6238 | A_33_P3220277 | 0.6809 | 0.1272 | |
| SRP007169 | RRBP1 | 6238 | RNAseq | 0.9331 | 0.0498 | |
| SRP008496 | RRBP1 | 6238 | RNAseq | 0.7682 | 0.0190 | |
| SRP064894 | RRBP1 | 6238 | RNAseq | 0.4195 | 0.0056 | |
| SRP133303 | RRBP1 | 6238 | RNAseq | 0.3734 | 0.0315 | |
| SRP159526 | RRBP1 | 6238 | RNAseq | 0.3749 | 0.1856 | |
| SRP193095 | RRBP1 | 6238 | RNAseq | 0.2097 | 0.3616 | |
| SRP219564 | RRBP1 | 6238 | RNAseq | 0.8900 | 0.0040 | |
| TCGA | RRBP1 | 6238 | RNAseq | -0.1736 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RRBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RRBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RRBP1 | 6238 | 12 | 3 | 15 | |
| GSE20123 | RRBP1 | 6238 | 12 | 3 | 15 | |
| GSE43470 | RRBP1 | 6238 | 11 | 1 | 31 | |
| GSE46452 | RRBP1 | 6238 | 27 | 1 | 31 | |
| GSE47630 | RRBP1 | 6238 | 17 | 4 | 19 | |
| GSE54993 | RRBP1 | 6238 | 0 | 15 | 55 | |
| GSE54994 | RRBP1 | 6238 | 26 | 2 | 25 | |
| GSE60625 | RRBP1 | 6238 | 0 | 0 | 11 | |
| GSE74703 | RRBP1 | 6238 | 8 | 1 | 27 | |
| GSE74704 | RRBP1 | 6238 | 7 | 2 | 11 | |
| TCGA | RRBP1 | 6238 | 43 | 10 | 43 |
Total number of gains: 163; Total number of losses: 42; Total Number of normals: 283.
Somatic mutations of RRBP1:
Generating mutation plots.
Highly correlated genes for RRBP1:
Showing top 20/254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RRBP1 | UBE2J2 | 0.808261 | 3 | 0 | 3 |
| RRBP1 | ATAD3B | 0.749978 | 3 | 0 | 3 |
| RRBP1 | ZNF468 | 0.712623 | 3 | 0 | 3 |
| RRBP1 | AP5S1 | 0.69498 | 6 | 0 | 5 |
| RRBP1 | APLNR | 0.683826 | 3 | 0 | 3 |
| RRBP1 | GALNT10 | 0.682688 | 4 | 0 | 4 |
| RRBP1 | KDM1B | 0.680267 | 3 | 0 | 3 |
| RRBP1 | PFAS | 0.677205 | 4 | 0 | 3 |
| RRBP1 | FNDC1 | 0.671261 | 3 | 0 | 3 |
| RRBP1 | FAP | 0.66495 | 4 | 0 | 3 |
| RRBP1 | HDAC7 | 0.660836 | 4 | 0 | 4 |
| RRBP1 | MMP3 | 0.659718 | 4 | 0 | 4 |
| RRBP1 | GEN1 | 0.656723 | 3 | 0 | 3 |
| RRBP1 | BIN3 | 0.656065 | 3 | 0 | 3 |
| RRBP1 | SMPDL3B | 0.651653 | 3 | 0 | 3 |
| RRBP1 | TRMT6 | 0.650269 | 4 | 0 | 4 |
| RRBP1 | DGKQ | 0.649712 | 5 | 0 | 4 |
| RRBP1 | DBR1 | 0.649348 | 3 | 0 | 3 |
| RRBP1 | CCDC137 | 0.649056 | 4 | 0 | 4 |
| RRBP1 | TMEM86B | 0.638495 | 4 | 0 | 3 |
For details and further investigation, click here
