| Full name: RNA polymerase III subunit H | Alias Symbol: RPC8|KIAA1665 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 171568 | HGNC ID: HGNC:30349 | Ensembl Gene: ENSG00000100413 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of POLR3H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR3H | 171568 | 225682_s_at | 0.5137 | 0.0399 | |
| GSE26886 | POLR3H | 171568 | 225682_s_at | -0.1933 | 0.1161 | |
| GSE45670 | POLR3H | 171568 | 225682_s_at | 0.2495 | 0.0568 | |
| GSE53622 | POLR3H | 171568 | 79910 | 0.2962 | 0.0000 | |
| GSE53624 | POLR3H | 171568 | 86827 | 0.3275 | 0.0000 | |
| GSE63941 | POLR3H | 171568 | 225678_at | -0.0055 | 0.9851 | |
| GSE77861 | POLR3H | 171568 | 225682_s_at | 0.0560 | 0.7136 | |
| GSE97050 | POLR3H | 171568 | A_24_P322847 | -0.1391 | 0.6110 | |
| SRP007169 | POLR3H | 171568 | RNAseq | 0.2819 | 0.5197 | |
| SRP008496 | POLR3H | 171568 | RNAseq | 0.2901 | 0.3665 | |
| SRP064894 | POLR3H | 171568 | RNAseq | 0.8274 | 0.0011 | |
| SRP133303 | POLR3H | 171568 | RNAseq | -0.1490 | 0.3885 | |
| SRP159526 | POLR3H | 171568 | RNAseq | 0.2693 | 0.2233 | |
| SRP193095 | POLR3H | 171568 | RNAseq | 0.2590 | 0.0072 | |
| SRP219564 | POLR3H | 171568 | RNAseq | 0.1686 | 0.5206 | |
| TCGA | POLR3H | 171568 | RNAseq | -0.0095 | 0.8466 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POLR3H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR3H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR3H | 171568 | 6 | 5 | 19 | |
| GSE20123 | POLR3H | 171568 | 6 | 4 | 20 | |
| GSE43470 | POLR3H | 171568 | 5 | 6 | 32 | |
| GSE46452 | POLR3H | 171568 | 31 | 2 | 26 | |
| GSE47630 | POLR3H | 171568 | 9 | 4 | 27 | |
| GSE54993 | POLR3H | 171568 | 3 | 6 | 61 | |
| GSE54994 | POLR3H | 171568 | 11 | 8 | 34 | |
| GSE60625 | POLR3H | 171568 | 5 | 0 | 6 | |
| GSE74703 | POLR3H | 171568 | 5 | 4 | 27 | |
| GSE74704 | POLR3H | 171568 | 3 | 2 | 15 | |
| TCGA | POLR3H | 171568 | 26 | 14 | 56 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of POLR3H:
Generating mutation plots.
Highly correlated genes for POLR3H:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR3H | TMEM160 | 0.68533 | 4 | 0 | 3 |
| POLR3H | DDX11 | 0.678296 | 3 | 0 | 3 |
| POLR3H | ATAD3B | 0.672698 | 3 | 0 | 3 |
| POLR3H | PNKP | 0.662454 | 3 | 0 | 3 |
| POLR3H | EHMT2 | 0.650954 | 3 | 0 | 3 |
| POLR3H | MSTO1 | 0.650151 | 3 | 0 | 3 |
| POLR3H | UBA1 | 0.648185 | 4 | 0 | 4 |
| POLR3H | MCAT | 0.647786 | 5 | 0 | 5 |
| POLR3H | ZNF683 | 0.645408 | 3 | 0 | 3 |
| POLR3H | ZNF324B | 0.638814 | 3 | 0 | 3 |
| POLR3H | EXOSC4 | 0.63254 | 6 | 0 | 5 |
| POLR3H | HYOU1 | 0.631718 | 4 | 0 | 3 |
| POLR3H | SURF6 | 0.626024 | 3 | 0 | 3 |
| POLR3H | OPLAH | 0.625205 | 3 | 0 | 3 |
| POLR3H | NDUFS6 | 0.624011 | 3 | 0 | 3 |
| POLR3H | CLCN7 | 0.622733 | 4 | 0 | 3 |
| POLR3H | SLC35A2 | 0.622134 | 4 | 0 | 3 |
| POLR3H | DDX49 | 0.617613 | 3 | 0 | 3 |
| POLR3H | JMJD4 | 0.615068 | 5 | 0 | 3 |
| POLR3H | TUBA1B | 0.611596 | 3 | 0 | 3 |
For details and further investigation, click here
