| Full name: atonal bHLH transcription factor 1 | Alias Symbol: HATH1|MATH-1|Math1|bHLHa14 | ||
| Type: protein-coding gene | Cytoband: 4q22.2 | ||
| Entrez ID: 474 | HGNC ID: HGNC:797 | Ensembl Gene: ENSG00000172238 | OMIM ID: 601461 |
| Drug and gene relationship at DGIdb | |||
Expression of ATOH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATOH1 | 474 | 221336_at | -0.1307 | 0.5730 | |
| GSE20347 | ATOH1 | 474 | 221336_at | -0.0757 | 0.3333 | |
| GSE23400 | ATOH1 | 474 | 221336_at | -0.1386 | 0.0000 | |
| GSE26886 | ATOH1 | 474 | 221336_at | 0.0943 | 0.5502 | |
| GSE29001 | ATOH1 | 474 | 221336_at | -0.2112 | 0.0957 | |
| GSE38129 | ATOH1 | 474 | 221336_at | -0.1632 | 0.1486 | |
| GSE45670 | ATOH1 | 474 | 221336_at | 0.0458 | 0.5240 | |
| GSE53622 | ATOH1 | 474 | 20012 | 0.1634 | 0.3490 | |
| GSE53624 | ATOH1 | 474 | 20012 | 0.5479 | 0.0001 | |
| GSE63941 | ATOH1 | 474 | 221336_at | 0.5927 | 0.0070 | |
| GSE77861 | ATOH1 | 474 | 221336_at | -0.0640 | 0.7153 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATOH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATOH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATOH1 | 474 | 0 | 12 | 18 | |
| GSE20123 | ATOH1 | 474 | 0 | 12 | 18 | |
| GSE43470 | ATOH1 | 474 | 0 | 16 | 27 | |
| GSE46452 | ATOH1 | 474 | 1 | 36 | 22 | |
| GSE47630 | ATOH1 | 474 | 0 | 20 | 20 | |
| GSE54993 | ATOH1 | 474 | 8 | 0 | 62 | |
| GSE54994 | ATOH1 | 474 | 1 | 11 | 41 | |
| GSE60625 | ATOH1 | 474 | 0 | 3 | 8 | |
| GSE74703 | ATOH1 | 474 | 0 | 14 | 22 | |
| GSE74704 | ATOH1 | 474 | 0 | 6 | 14 | |
| TCGA | ATOH1 | 474 | 9 | 38 | 49 |
Total number of gains: 19; Total number of losses: 168; Total Number of normals: 301.
Somatic mutations of ATOH1:
Generating mutation plots.
Highly correlated genes for ATOH1:
Showing top 20/712 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATOH1 | ATN1 | 0.707513 | 4 | 0 | 4 |
| ATOH1 | SLC13A3 | 0.691981 | 3 | 0 | 3 |
| ATOH1 | WT1 | 0.691558 | 4 | 0 | 4 |
| ATOH1 | PIK3R5 | 0.679879 | 3 | 0 | 3 |
| ATOH1 | TGIF2LY | 0.670824 | 3 | 0 | 3 |
| ATOH1 | CD300C | 0.669025 | 3 | 0 | 3 |
| ATOH1 | SLC10A1 | 0.665774 | 7 | 0 | 6 |
| ATOH1 | CER1 | 0.664521 | 5 | 0 | 5 |
| ATOH1 | SBNO2 | 0.658073 | 4 | 0 | 3 |
| ATOH1 | ARRB2 | 0.657014 | 3 | 0 | 3 |
| ATOH1 | NPFFR1 | 0.656015 | 3 | 0 | 3 |
| ATOH1 | CA5B | 0.655867 | 4 | 0 | 3 |
| ATOH1 | PDYN | 0.65344 | 5 | 0 | 4 |
| ATOH1 | APOA4 | 0.650914 | 4 | 0 | 3 |
| ATOH1 | ESR2 | 0.647862 | 3 | 0 | 3 |
| ATOH1 | DEFB108B | 0.647228 | 3 | 0 | 3 |
| ATOH1 | SLC22A13 | 0.644487 | 5 | 0 | 4 |
| ATOH1 | KLF15 | 0.64307 | 4 | 0 | 4 |
| ATOH1 | PSG2 | 0.642331 | 4 | 0 | 4 |
| ATOH1 | TOM1L2 | 0.64184 | 4 | 0 | 3 |
For details and further investigation, click here
