| Full name: gap junction protein gamma 2 | Alias Symbol: CX47|CX46.6|SPG44 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 57165 | HGNC ID: HGNC:17494 | Ensembl Gene: ENSG00000198835 | OMIM ID: 608803 |
| Drug and gene relationship at DGIdb | |||
Expression of GJC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GJC2 | 57165 | 207025_at | -0.0434 | 0.8271 | |
| GSE20347 | GJC2 | 57165 | 207025_at | -0.2100 | 0.0022 | |
| GSE23400 | GJC2 | 57165 | 207025_at | -0.3157 | 0.0000 | |
| GSE26886 | GJC2 | 57165 | 207025_at | 0.0868 | 0.5217 | |
| GSE29001 | GJC2 | 57165 | 207025_at | -0.3268 | 0.0481 | |
| GSE38129 | GJC2 | 57165 | 207025_at | -0.3351 | 0.0004 | |
| GSE45670 | GJC2 | 57165 | 207025_at | -0.0994 | 0.3267 | |
| GSE53622 | GJC2 | 57165 | 71967 | -0.4853 | 0.0000 | |
| GSE53624 | GJC2 | 57165 | 71967 | -0.1686 | 0.0491 | |
| GSE63941 | GJC2 | 57165 | 207025_at | -0.1250 | 0.5061 | |
| GSE77861 | GJC2 | 57165 | 207025_at | -0.2951 | 0.0845 | |
| GSE97050 | GJC2 | 57165 | A_33_P3422822 | -0.2372 | 0.6392 | |
| SRP133303 | GJC2 | 57165 | RNAseq | -0.9025 | 0.0074 | |
| SRP159526 | GJC2 | 57165 | RNAseq | -0.3484 | 0.5118 | |
| SRP219564 | GJC2 | 57165 | RNAseq | -1.1116 | 0.1837 | |
| TCGA | GJC2 | 57165 | RNAseq | -0.5334 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GJC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GJC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GJC2 | 57165 | 11 | 0 | 19 | |
| GSE20123 | GJC2 | 57165 | 11 | 0 | 19 | |
| GSE43470 | GJC2 | 57165 | 7 | 1 | 35 | |
| GSE46452 | GJC2 | 57165 | 4 | 2 | 53 | |
| GSE47630 | GJC2 | 57165 | 15 | 0 | 25 | |
| GSE54993 | GJC2 | 57165 | 0 | 6 | 64 | |
| GSE54994 | GJC2 | 57165 | 17 | 0 | 36 | |
| GSE60625 | GJC2 | 57165 | 0 | 0 | 11 | |
| GSE74703 | GJC2 | 57165 | 7 | 1 | 28 | |
| GSE74704 | GJC2 | 57165 | 5 | 0 | 15 | |
| TCGA | GJC2 | 57165 | 45 | 2 | 49 |
Total number of gains: 122; Total number of losses: 12; Total Number of normals: 354.
Somatic mutations of GJC2:
Generating mutation plots.
Highly correlated genes for GJC2:
Showing top 20/1141 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GJC2 | PERM1 | 0.766576 | 3 | 0 | 3 |
| GJC2 | TOX | 0.749671 | 3 | 0 | 3 |
| GJC2 | STBD1 | 0.737154 | 4 | 0 | 3 |
| GJC2 | GRHPR | 0.7316 | 3 | 0 | 3 |
| GJC2 | C9orf50 | 0.727071 | 4 | 0 | 4 |
| GJC2 | ATN1 | 0.712693 | 3 | 0 | 3 |
| GJC2 | SERTAD1 | 0.712604 | 4 | 0 | 4 |
| GJC2 | VWA7 | 0.708081 | 6 | 0 | 6 |
| GJC2 | GABRR2 | 0.701045 | 6 | 0 | 6 |
| GJC2 | POU6F1 | 0.698121 | 8 | 0 | 8 |
| GJC2 | FAM99B | 0.69043 | 3 | 0 | 3 |
| GJC2 | INPP5K | 0.689026 | 3 | 0 | 3 |
| GJC2 | CLDN18 | 0.686775 | 3 | 0 | 3 |
| GJC2 | APOA4 | 0.68644 | 7 | 0 | 6 |
| GJC2 | GIPC3 | 0.682969 | 4 | 0 | 4 |
| GJC2 | ACOT11 | 0.680933 | 5 | 0 | 5 |
| GJC2 | KIAA1211L | 0.68091 | 4 | 0 | 4 |
| GJC2 | SHBG | 0.679956 | 5 | 0 | 4 |
| GJC2 | TTLL11 | 0.6799 | 3 | 0 | 3 |
| GJC2 | MVK | 0.679806 | 6 | 0 | 5 |
For details and further investigation, click here
