| Full name: ATPase Na+/K+ transporting subunit beta 2 | Alias Symbol: AMOG | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 482 | HGNC ID: HGNC:805 | Ensembl Gene: ENSG00000129244 | OMIM ID: 182331 |
| Drug and gene relationship at DGIdb | |||
ATP1B2 involved pathways:
Expression of ATP1B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP1B2 | 482 | 204311_at | -0.4144 | 0.1170 | |
| GSE20347 | ATP1B2 | 482 | 204311_at | -0.0564 | 0.4939 | |
| GSE23400 | ATP1B2 | 482 | 204311_at | -0.0674 | 0.1063 | |
| GSE26886 | ATP1B2 | 482 | 204311_at | -0.0982 | 0.4129 | |
| GSE29001 | ATP1B2 | 482 | 204311_at | -0.3271 | 0.1145 | |
| GSE38129 | ATP1B2 | 482 | 204311_at | -0.5086 | 0.0002 | |
| GSE45670 | ATP1B2 | 482 | 204311_at | -0.2668 | 0.0019 | |
| GSE53622 | ATP1B2 | 482 | 27153 | -1.7175 | 0.0000 | |
| GSE53624 | ATP1B2 | 482 | 27153 | -1.5642 | 0.0000 | |
| GSE63941 | ATP1B2 | 482 | 204311_at | 0.3379 | 0.0850 | |
| GSE77861 | ATP1B2 | 482 | 204311_at | -0.0122 | 0.9357 | |
| GSE97050 | ATP1B2 | 482 | A_24_P31275 | -0.5781 | 0.2713 | |
| SRP064894 | ATP1B2 | 482 | RNAseq | -0.5794 | 0.0708 | |
| SRP133303 | ATP1B2 | 482 | RNAseq | -1.1614 | 0.0000 | |
| SRP159526 | ATP1B2 | 482 | RNAseq | -0.0041 | 0.9943 | |
| SRP193095 | ATP1B2 | 482 | RNAseq | -0.1776 | 0.2791 | |
| SRP219564 | ATP1B2 | 482 | RNAseq | -0.5161 | 0.4450 | |
| TCGA | ATP1B2 | 482 | RNAseq | -0.9370 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ATP1B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP1B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP1B2 | 482 | 4 | 2 | 24 | |
| GSE20123 | ATP1B2 | 482 | 4 | 3 | 23 | |
| GSE43470 | ATP1B2 | 482 | 1 | 6 | 36 | |
| GSE46452 | ATP1B2 | 482 | 34 | 1 | 24 | |
| GSE47630 | ATP1B2 | 482 | 7 | 1 | 32 | |
| GSE54993 | ATP1B2 | 482 | 4 | 3 | 63 | |
| GSE54994 | ATP1B2 | 482 | 5 | 8 | 40 | |
| GSE60625 | ATP1B2 | 482 | 4 | 0 | 7 | |
| GSE74703 | ATP1B2 | 482 | 1 | 3 | 32 | |
| GSE74704 | ATP1B2 | 482 | 2 | 1 | 17 | |
| TCGA | ATP1B2 | 482 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of ATP1B2:
Generating mutation plots.
Highly correlated genes for ATP1B2:
Showing top 20/781 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP1B2 | CYP21A2 | 0.869136 | 3 | 0 | 3 |
| ATP1B2 | CLEC3B | 0.843258 | 3 | 0 | 3 |
| ATP1B2 | CADM2 | 0.79847 | 3 | 0 | 3 |
| ATP1B2 | TNFSF12 | 0.77105 | 3 | 0 | 3 |
| ATP1B2 | RBFOX3 | 0.76354 | 3 | 0 | 3 |
| ATP1B2 | GPRASP2 | 0.752243 | 3 | 0 | 3 |
| ATP1B2 | CCL14 | 0.746785 | 3 | 0 | 3 |
| ATP1B2 | NR2F1 | 0.745262 | 3 | 0 | 3 |
| ATP1B2 | EIF4E3 | 0.724277 | 5 | 0 | 5 |
| ATP1B2 | RAB9B | 0.722153 | 5 | 0 | 5 |
| ATP1B2 | XKR4 | 0.721771 | 5 | 0 | 4 |
| ATP1B2 | RBPMS2 | 0.713727 | 5 | 0 | 4 |
| ATP1B2 | MAMDC2 | 0.712083 | 5 | 0 | 4 |
| ATP1B2 | SORCS1 | 0.710408 | 5 | 0 | 4 |
| ATP1B2 | DGKB | 0.706725 | 5 | 0 | 5 |
| ATP1B2 | CELF2 | 0.701456 | 5 | 0 | 4 |
| ATP1B2 | RAB1B | 0.701301 | 3 | 0 | 3 |
| ATP1B2 | MUC6 | 0.698767 | 3 | 0 | 3 |
| ATP1B2 | LTBP4 | 0.697327 | 6 | 0 | 6 |
| ATP1B2 | C1QTNF7 | 0.694427 | 6 | 0 | 5 |
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