| Full name: diacylglycerol kinase beta | Alias Symbol: KIAA0718|DGK|DGK-BETA | ||
| Type: protein-coding gene | Cytoband: 7p21.2 | ||
| Entrez ID: 1607 | HGNC ID: HGNC:2850 | Ensembl Gene: ENSG00000136267 | OMIM ID: 604070 |
| Drug and gene relationship at DGIdb | |||
Expression of DGKB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGKB | 1607 | 1553524_at | -0.0727 | 0.8022 | |
| GSE20347 | DGKB | 1607 | 216307_at | 0.0028 | 0.9750 | |
| GSE23400 | DGKB | 1607 | 216307_at | -0.2203 | 0.0000 | |
| GSE26886 | DGKB | 1607 | 216307_at | 0.1600 | 0.1046 | |
| GSE29001 | DGKB | 1607 | 216307_at | 0.0448 | 0.7235 | |
| GSE38129 | DGKB | 1607 | 216307_at | -0.2522 | 0.1435 | |
| GSE45670 | DGKB | 1607 | 1553524_at | -0.0400 | 0.6269 | |
| GSE53622 | DGKB | 1607 | 16636 | -1.9282 | 0.0000 | |
| GSE53624 | DGKB | 1607 | 16636 | -0.9635 | 0.0000 | |
| GSE63941 | DGKB | 1607 | 216307_at | 0.0040 | 0.9848 | |
| GSE77861 | DGKB | 1607 | 1553524_at | -0.0208 | 0.8414 | |
| GSE97050 | DGKB | 1607 | A_33_P3310172 | -1.3341 | 0.1600 | |
| SRP133303 | DGKB | 1607 | RNAseq | -1.6530 | 0.0000 | |
| TCGA | DGKB | 1607 | RNAseq | -0.9910 | 0.0666 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DGKB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGKB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGKB | 1607 | 14 | 2 | 14 | |
| GSE20123 | DGKB | 1607 | 14 | 2 | 14 | |
| GSE43470 | DGKB | 1607 | 5 | 0 | 38 | |
| GSE46452 | DGKB | 1607 | 11 | 1 | 47 | |
| GSE47630 | DGKB | 1607 | 9 | 1 | 30 | |
| GSE54993 | DGKB | 1607 | 0 | 6 | 64 | |
| GSE54994 | DGKB | 1607 | 21 | 1 | 31 | |
| GSE60625 | DGKB | 1607 | 0 | 0 | 11 | |
| GSE74703 | DGKB | 1607 | 5 | 0 | 31 | |
| GSE74704 | DGKB | 1607 | 8 | 2 | 10 | |
| TCGA | DGKB | 1607 | 55 | 6 | 35 |
Total number of gains: 142; Total number of losses: 21; Total Number of normals: 325.
Somatic mutations of DGKB:
Generating mutation plots.
Highly correlated genes for DGKB:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGKB | MYOCD | 0.826458 | 3 | 0 | 3 |
| DGKB | RBPMS2 | 0.787304 | 3 | 0 | 3 |
| DGKB | GIPC3 | 0.767547 | 4 | 0 | 4 |
| DGKB | SLC35F1 | 0.754903 | 3 | 0 | 3 |
| DGKB | CYP21A2 | 0.753092 | 3 | 0 | 3 |
| DGKB | MAMDC2 | 0.751939 | 3 | 0 | 3 |
| DGKB | KCNMB1 | 0.751272 | 6 | 0 | 6 |
| DGKB | PPP1R14A | 0.748645 | 4 | 0 | 3 |
| DGKB | MRVI1 | 0.74809 | 3 | 0 | 3 |
| DGKB | BHMT2 | 0.741687 | 6 | 0 | 6 |
| DGKB | CADM2 | 0.741135 | 4 | 0 | 3 |
| DGKB | CTNNA3 | 0.736733 | 4 | 0 | 3 |
| DGKB | ACTBL2 | 0.735478 | 3 | 0 | 3 |
| DGKB | TNS1 | 0.733608 | 5 | 0 | 5 |
| DGKB | C3orf70 | 0.729533 | 3 | 0 | 3 |
| DGKB | ADCY5 | 0.728427 | 4 | 0 | 3 |
| DGKB | RBFOX3 | 0.726334 | 3 | 0 | 3 |
| DGKB | SLITRK3 | 0.724559 | 6 | 0 | 6 |
| DGKB | ADAMTSL1 | 0.717037 | 4 | 0 | 4 |
| DGKB | VMAC | 0.715295 | 3 | 0 | 3 |
For details and further investigation, click here
