| Full name: protein phosphatase, Mg2+/Mn2+ dependent 1M | Alias Symbol: PP2Ceta|FLJ32332 | ||
| Type: protein-coding gene | Cytoband: 3p21.2 | ||
| Entrez ID: 132160 | HGNC ID: HGNC:26506 | Ensembl Gene: ENSG00000164088 | OMIM ID: 608979 |
| Drug and gene relationship at DGIdb | |||
Expression of PPM1M:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPM1M | 132160 | 226074_at | -0.1529 | 0.6977 | |
| GSE26886 | PPM1M | 132160 | 226074_at | -0.3167 | 0.1133 | |
| GSE45670 | PPM1M | 132160 | 226074_at | -0.5093 | 0.0017 | |
| GSE53622 | PPM1M | 132160 | 131768 | -0.6100 | 0.0000 | |
| GSE53624 | PPM1M | 132160 | 131768 | -0.6907 | 0.0000 | |
| GSE63941 | PPM1M | 132160 | 226074_at | -0.6474 | 0.1673 | |
| GSE77861 | PPM1M | 132160 | 226074_at | -0.2873 | 0.1984 | |
| GSE97050 | PPM1M | 132160 | A_23_P258393 | -0.1786 | 0.4397 | |
| SRP007169 | PPM1M | 132160 | RNAseq | -0.8725 | 0.1222 | |
| SRP008496 | PPM1M | 132160 | RNAseq | -0.4561 | 0.1851 | |
| SRP064894 | PPM1M | 132160 | RNAseq | -0.0226 | 0.9302 | |
| SRP133303 | PPM1M | 132160 | RNAseq | -0.8909 | 0.0000 | |
| SRP159526 | PPM1M | 132160 | RNAseq | -0.9010 | 0.0012 | |
| SRP193095 | PPM1M | 132160 | RNAseq | -0.4979 | 0.0002 | |
| SRP219564 | PPM1M | 132160 | RNAseq | -0.4239 | 0.1029 | |
| TCGA | PPM1M | 132160 | RNAseq | -0.1712 | 0.0307 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPM1M expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPM1M:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPM1M | 132160 | 0 | 18 | 12 | |
| GSE20123 | PPM1M | 132160 | 0 | 19 | 11 | |
| GSE43470 | PPM1M | 132160 | 0 | 18 | 25 | |
| GSE46452 | PPM1M | 132160 | 2 | 17 | 40 | |
| GSE47630 | PPM1M | 132160 | 1 | 24 | 15 | |
| GSE54993 | PPM1M | 132160 | 6 | 2 | 62 | |
| GSE54994 | PPM1M | 132160 | 0 | 34 | 19 | |
| GSE60625 | PPM1M | 132160 | 5 | 0 | 6 | |
| GSE74703 | PPM1M | 132160 | 0 | 14 | 22 | |
| GSE74704 | PPM1M | 132160 | 0 | 12 | 8 | |
| TCGA | PPM1M | 132160 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 236; Total Number of normals: 238.
Somatic mutations of PPM1M:
Generating mutation plots.
Highly correlated genes for PPM1M:
Showing top 20/937 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPM1M | CCL14 | 0.767628 | 3 | 0 | 3 |
| PPM1M | MAN1C1 | 0.744377 | 5 | 0 | 5 |
| PPM1M | C2CD2 | 0.729541 | 3 | 0 | 3 |
| PPM1M | CLEC3B | 0.729392 | 3 | 0 | 3 |
| PPM1M | TTC17 | 0.719267 | 3 | 0 | 3 |
| PPM1M | CYP21A2 | 0.702111 | 3 | 0 | 3 |
| PPM1M | CCNG1 | 0.699167 | 5 | 0 | 5 |
| PPM1M | HOXA4 | 0.697242 | 3 | 0 | 3 |
| PPM1M | GAB3 | 0.696057 | 6 | 0 | 6 |
| PPM1M | VAMP1 | 0.695681 | 3 | 0 | 3 |
| PPM1M | CELF2 | 0.693449 | 5 | 0 | 5 |
| PPM1M | SMTNL2 | 0.69269 | 5 | 0 | 5 |
| PPM1M | ATP8A1 | 0.691809 | 7 | 0 | 6 |
| PPM1M | SLC25A6 | 0.687729 | 3 | 0 | 3 |
| PPM1M | MYO9A | 0.687382 | 3 | 0 | 3 |
| PPM1M | HPGDS | 0.683932 | 4 | 0 | 4 |
| PPM1M | N4BP2L1 | 0.682988 | 6 | 0 | 5 |
| PPM1M | CXorf40B | 0.680245 | 3 | 0 | 3 |
| PPM1M | WDR48 | 0.678188 | 4 | 0 | 3 |
| PPM1M | MSRA | 0.673724 | 6 | 0 | 5 |
For details and further investigation, click here
