| Full name: myotubularin related protein 3 | Alias Symbol: KIAA0371|ZFYVE10|FYVE-DSP1 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 8897 | HGNC ID: HGNC:7451 | Ensembl Gene: ENSG00000100330 | OMIM ID: 603558 |
| Drug and gene relationship at DGIdb | |||
Expression of MTMR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR3 | 8897 | 202197_at | -0.4047 | 0.3483 | |
| GSE20347 | MTMR3 | 8897 | 202197_at | -0.6930 | 0.0000 | |
| GSE23400 | MTMR3 | 8897 | 202197_at | -0.6048 | 0.0000 | |
| GSE26886 | MTMR3 | 8897 | 202197_at | -1.3631 | 0.0000 | |
| GSE29001 | MTMR3 | 8897 | 202197_at | -0.7297 | 0.0004 | |
| GSE38129 | MTMR3 | 8897 | 202197_at | -0.6061 | 0.0000 | |
| GSE45670 | MTMR3 | 8897 | 202197_at | -0.3188 | 0.0385 | |
| GSE53622 | MTMR3 | 8897 | 19825 | -0.5891 | 0.0000 | |
| GSE53624 | MTMR3 | 8897 | 19825 | -0.6683 | 0.0000 | |
| GSE63941 | MTMR3 | 8897 | 202197_at | -0.6461 | 0.0476 | |
| GSE77861 | MTMR3 | 8897 | 202197_at | -0.5257 | 0.0100 | |
| GSE97050 | MTMR3 | 8897 | A_33_P3235335 | -0.0385 | 0.8676 | |
| SRP007169 | MTMR3 | 8897 | RNAseq | -1.0100 | 0.0300 | |
| SRP008496 | MTMR3 | 8897 | RNAseq | -0.8794 | 0.0010 | |
| SRP064894 | MTMR3 | 8897 | RNAseq | -0.8583 | 0.0000 | |
| SRP133303 | MTMR3 | 8897 | RNAseq | -0.6006 | 0.0000 | |
| SRP159526 | MTMR3 | 8897 | RNAseq | -0.8158 | 0.0002 | |
| SRP193095 | MTMR3 | 8897 | RNAseq | -0.7495 | 0.0000 | |
| SRP219564 | MTMR3 | 8897 | RNAseq | -0.7108 | 0.1113 | |
| TCGA | MTMR3 | 8897 | RNAseq | -0.1670 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MTMR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR3 | 8897 | 5 | 5 | 20 | |
| GSE20123 | MTMR3 | 8897 | 5 | 4 | 21 | |
| GSE43470 | MTMR3 | 8897 | 4 | 6 | 33 | |
| GSE46452 | MTMR3 | 8897 | 31 | 1 | 27 | |
| GSE47630 | MTMR3 | 8897 | 8 | 5 | 27 | |
| GSE54993 | MTMR3 | 8897 | 3 | 6 | 61 | |
| GSE54994 | MTMR3 | 8897 | 11 | 9 | 33 | |
| GSE60625 | MTMR3 | 8897 | 5 | 0 | 6 | |
| GSE74703 | MTMR3 | 8897 | 4 | 5 | 27 | |
| GSE74704 | MTMR3 | 8897 | 2 | 1 | 17 | |
| TCGA | MTMR3 | 8897 | 27 | 15 | 54 |
Total number of gains: 105; Total number of losses: 57; Total Number of normals: 326.
Somatic mutations of MTMR3:
Generating mutation plots.
Highly correlated genes for MTMR3:
Showing top 20/1444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR3 | RNASE7 | 0.796816 | 3 | 0 | 3 |
| MTMR3 | HMGN1 | 0.794918 | 3 | 0 | 3 |
| MTMR3 | EPS8L1 | 0.792578 | 8 | 0 | 8 |
| MTMR3 | PIM1 | 0.771291 | 9 | 0 | 8 |
| MTMR3 | ZNF175 | 0.766264 | 3 | 0 | 3 |
| MTMR3 | GFOD2 | 0.765327 | 7 | 0 | 7 |
| MTMR3 | ZFAND2B | 0.763497 | 5 | 0 | 5 |
| MTMR3 | BACH1 | 0.755768 | 6 | 0 | 6 |
| MTMR3 | RBM20 | 0.753991 | 4 | 0 | 4 |
| MTMR3 | LAPTM4A | 0.753944 | 4 | 0 | 4 |
| MTMR3 | CEPT1 | 0.753624 | 4 | 0 | 4 |
| MTMR3 | TOM1 | 0.748187 | 11 | 0 | 10 |
| MTMR3 | TJP3 | 0.74696 | 9 | 0 | 9 |
| MTMR3 | ANKRD44 | 0.745989 | 3 | 0 | 3 |
| MTMR3 | ZNF416 | 0.744835 | 5 | 0 | 5 |
| MTMR3 | AZI2 | 0.743176 | 5 | 0 | 5 |
| MTMR3 | DOCK9 | 0.734895 | 10 | 0 | 9 |
| MTMR3 | KLF8 | 0.733706 | 9 | 0 | 8 |
| MTMR3 | UPK1A | 0.733306 | 8 | 0 | 7 |
| MTMR3 | C18orf25 | 0.730066 | 10 | 0 | 9 |
For details and further investigation, click here
