BCAM

 

Full name: basal cell adhesion molecule (Lutheran blood group) Alias Symbol: CD239
Type: protein-coding gene Cytoband: 19q13.32
Entrez ID: 4059 HGNC ID: HGNC:6722 Ensembl Gene: ENSG00000187244 OMIM ID: 612773
Drug and gene relationship at DGIdb

 

Expression of BCAM:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCAM 4059 40093_at 0.5592 0.1717
GSE20347 BCAM 4059 40093_at 0.5804 0.0002
GSE23400 BCAM 4059 40093_at 0.5456 0.0000
GSE26886 BCAM 4059 40093_at 0.5948 0.0000
GSE29001 BCAM 4059 40093_at 0.1327 0.5962
GSE38129 BCAM 4059 40093_at 0.3016 0.1082
GSE45670 BCAM 4059 40093_at 0.1245 0.5316
GSE53622 BCAM 4059 38073 -0.1327 0.3364
GSE53624 BCAM 4059 38073 -0.6407 0.0000
GSE63941 BCAM 4059 40093_at 1.7733 0.0057
GSE77861 BCAM 4059 40093_at 0.3331 0.0764
GSE97050 BCAM 4059 A_33_P3291097 0.0700 0.8389
SRP007169 BCAM 4059 RNAseq 2.3350 0.0009
SRP008496 BCAM 4059 RNAseq 2.0401 0.0000
SRP064894 BCAM 4059 RNAseq 0.8077 0.0090
SRP133303 BCAM 4059 RNAseq 0.3842 0.3045
SRP159526 BCAM 4059 RNAseq 1.6208 0.0020
SRP193095 BCAM 4059 RNAseq 1.4014 0.0000
SRP219564 BCAM 4059 RNAseq 0.1226 0.7752
TCGA BCAM 4059 RNAseq 0.1073 0.3193

Upregulated datasets: 5; Downregulated datasets: 0.  

 

Survival by BCAM expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of BCAM:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BCAM 4059 4 5 21
GSE20123 BCAM 4059 4 4 22
GSE43470 BCAM 4059 3 11 29
GSE46452 BCAM 4059 45 1 13
GSE47630 BCAM 4059 8 6 26
GSE54993 BCAM 4059 17 4 49
GSE54994 BCAM 4059 6 12 35
GSE60625 BCAM 4059 9 0 2
GSE74703 BCAM 4059 3 7 26
GSE74704 BCAM 4059 4 2 14
TCGA BCAM 4059 14 17 65

Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.  

 

Somatic mutations of BCAM:

 

Generating mutation plots.

 

Highly correlated genes for BCAM:

 

Showing top 20/373 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCAMZIC20.756492404
BCAMQRFPR0.755347303
BCAMDNAH140.734039303
BCAMTP53I130.731144303
BCAMBRAT10.716574403
BCAMSTMN30.699875303
BCAMKIAA08950.697636303
BCAMFBRSL10.695329303
BCAMFAXC0.69374303
BCAMYDJC0.686393303
BCAMALKBH60.685697303
BCAMC11orf950.684906505
BCAMCCS0.68052303
BCAMSKIL0.680325303
BCAMMAP3K110.676925705
BCAMMSTO10.676422303
BCAMAUP10.6747303
BCAMRAI10.673268303
BCAMCNTD10.67182303
BCAMSLC7A50.668304303

For details and further investigation, click here