| Full name: failed axon connections homolog, metaxin like GST domain containing | Alias Symbol: MGC2817|dJ273F20 | ||
| Type: protein-coding gene | Cytoband: 6q16.2 | ||
| Entrez ID: 84553 | HGNC ID: HGNC:20742 | Ensembl Gene: ENSG00000146267 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAXC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAXC | 84553 | 232067_at | -0.5598 | 0.6551 | |
| GSE26886 | FAXC | 84553 | 232067_at | 1.8301 | 0.0012 | |
| GSE45670 | FAXC | 84553 | 232067_at | -0.3904 | 0.4932 | |
| GSE53622 | FAXC | 84553 | 140310 | -1.1043 | 0.0000 | |
| GSE53624 | FAXC | 84553 | 140310 | -0.3131 | 0.2274 | |
| GSE63941 | FAXC | 84553 | 232067_at | 1.3676 | 0.0527 | |
| GSE77861 | FAXC | 84553 | 232067_at | 1.0318 | 0.0291 | |
| SRP007169 | FAXC | 84553 | RNAseq | 2.4588 | 0.0085 | |
| SRP008496 | FAXC | 84553 | RNAseq | 2.7394 | 0.0000 | |
| SRP064894 | FAXC | 84553 | RNAseq | -0.2234 | 0.4403 | |
| SRP133303 | FAXC | 84553 | RNAseq | 0.3535 | 0.3438 | |
| SRP159526 | FAXC | 84553 | RNAseq | 1.0520 | 0.0000 | |
| SRP193095 | FAXC | 84553 | RNAseq | 1.1073 | 0.0000 | |
| SRP219564 | FAXC | 84553 | RNAseq | -0.4378 | 0.6030 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by FAXC expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FAXC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAXC | 84553 | 1 | 3 | 26 | |
| GSE20123 | FAXC | 84553 | 1 | 2 | 27 | |
| GSE43470 | FAXC | 84553 | 3 | 0 | 40 | |
| GSE46452 | FAXC | 84553 | 2 | 11 | 46 | |
| GSE47630 | FAXC | 84553 | 8 | 6 | 26 | |
| GSE54993 | FAXC | 84553 | 3 | 2 | 65 | |
| GSE54994 | FAXC | 84553 | 8 | 8 | 37 | |
| GSE60625 | FAXC | 84553 | 0 | 1 | 10 | |
| GSE74703 | FAXC | 84553 | 2 | 0 | 34 | |
| GSE74704 | FAXC | 84553 | 0 | 0 | 20 | |
| TCGA | FAXC | 84553 | 7 | 24 | 65 |
Total number of gains: 35; Total number of losses: 57; Total Number of normals: 396.
Somatic mutations of FAXC:
Generating mutation plots.
Highly correlated genes for FAXC:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAXC | ZIC2 | 0.720717 | 3 | 0 | 3 |
| FAXC | TMTC4 | 0.704182 | 3 | 0 | 3 |
| FAXC | GABRR1 | 0.702394 | 3 | 0 | 3 |
| FAXC | KCNE3 | 0.701988 | 4 | 0 | 4 |
| FAXC | DMRT2 | 0.698187 | 4 | 0 | 4 |
| FAXC | BCAM | 0.69374 | 3 | 0 | 3 |
| FAXC | PDE4D | 0.693618 | 5 | 0 | 5 |
| FAXC | SLC38A10 | 0.684876 | 3 | 0 | 3 |
| FAXC | EPS8 | 0.673204 | 5 | 0 | 5 |
| FAXC | APOD | 0.67051 | 3 | 0 | 3 |
| FAXC | CHST10 | 0.668904 | 4 | 0 | 3 |
| FAXC | TSPAN18 | 0.665558 | 6 | 0 | 5 |
| FAXC | VTCN1 | 0.662445 | 4 | 0 | 3 |
| FAXC | PLCB4 | 0.658583 | 6 | 0 | 5 |
| FAXC | CENPV | 0.658365 | 4 | 0 | 3 |
| FAXC | VPS13C | 0.655818 | 3 | 0 | 3 |
| FAXC | FBXO30 | 0.651542 | 4 | 0 | 4 |
| FAXC | NTRK2 | 0.649734 | 5 | 0 | 5 |
| FAXC | MARK1 | 0.649322 | 3 | 0 | 3 |
| FAXC | EDN1 | 0.648781 | 3 | 0 | 3 |
For details and further investigation, click here
