BCL2L14

 

Full name: BCL2 like 14 Alias Symbol: BCLG|BCL-G
Type: protein-coding gene Cytoband: 12p13.2
Entrez ID: 79370 HGNC ID: HGNC:16657 Ensembl Gene: ENSG00000121380 OMIM ID: 606126
Drug and gene relationship at DGIdb

 

Expression of BCL2L14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCL2L14 79370 221241_s_at 0.2242 0.5637
GSE20347 BCL2L14 79370 221241_s_at 0.0128 0.9097
GSE23400 BCL2L14 79370 221241_s_at -0.0587 0.1592
GSE26886 BCL2L14 79370 221241_s_at 0.2220 0.6000
GSE29001 BCL2L14 79370 221241_s_at 0.1467 0.5987
GSE38129 BCL2L14 79370 221241_s_at -0.1057 0.3997
GSE45670 BCL2L14 79370 221241_s_at 0.2379 0.1907
GSE53622 BCL2L14 79370 18538 0.4584 0.0006
GSE53624 BCL2L14 79370 22053 0.0990 0.6969
GSE63941 BCL2L14 79370 221241_s_at 0.7828 0.2523
GSE77861 BCL2L14 79370 221241_s_at -0.0309 0.8444
SRP133303 BCL2L14 79370 RNAseq 0.4856 0.2347
SRP159526 BCL2L14 79370 RNAseq 0.5525 0.4221
TCGA BCL2L14 79370 RNAseq -1.5452 0.0004

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by BCL2L14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BCL2L14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BCL2L14 79370 6 2 22
GSE20123 BCL2L14 79370 6 2 22
GSE43470 BCL2L14 79370 10 4 29
GSE46452 BCL2L14 79370 10 1 48
GSE47630 BCL2L14 79370 13 2 25
GSE54993 BCL2L14 79370 2 9 59
GSE54994 BCL2L14 79370 10 2 41
GSE60625 BCL2L14 79370 0 1 10
GSE74703 BCL2L14 79370 9 3 24
GSE74704 BCL2L14 79370 4 1 15
TCGA BCL2L14 79370 39 7 50

Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.  


 

Somatic mutations of BCL2L14:

 

Generating mutation plots.

 

Highly correlated genes for BCL2L14:

 

Showing top 20/210 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCL2L14TRDN0.670838303
BCL2L14CHAT0.654812404
BCL2L14REG3A0.627875404
BCL2L14BTN3A10.62256403
BCL2L14RORB0.619348503
BCL2L14SLA20.616572403
BCL2L14CD40.615588403
BCL2L14SLC30A30.613575303
BCL2L14ADAMDEC10.613304303
BCL2L14KRTAP5-80.609267303
BCL2L14SLC41A20.607957303
BCL2L14GYPA0.607788303
BCL2L14FCAR0.605047403
BCL2L14CAPN90.602247504
BCL2L14LUZP40.60183403
BCL2L14CTAGE10.600012504
BCL2L14CD400.596135504
BCL2L14SCN11A0.595321404
BCL2L14RBFADN0.594974404
BCL2L14CACNB10.591653303

For details and further investigation, click here