| Full name: calpain 9 | Alias Symbol: nCL-4|GC36 | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 10753 | HGNC ID: HGNC:1486 | Ensembl Gene: ENSG00000135773 | OMIM ID: 606401 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CAPN9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPN9 | 10753 | 208063_s_at | -0.0694 | 0.8705 | |
| GSE20347 | CAPN9 | 10753 | 208063_s_at | 0.0138 | 0.8745 | |
| GSE23400 | CAPN9 | 10753 | 210641_at | -0.0978 | 0.0886 | |
| GSE26886 | CAPN9 | 10753 | 208063_s_at | 0.4963 | 0.0001 | |
| GSE29001 | CAPN9 | 10753 | 208063_s_at | -0.0892 | 0.5851 | |
| GSE38129 | CAPN9 | 10753 | 208063_s_at | -0.2162 | 0.1991 | |
| GSE45670 | CAPN9 | 10753 | 208063_s_at | -0.0633 | 0.6293 | |
| GSE53622 | CAPN9 | 10753 | 12061 | -0.7686 | 0.0037 | |
| GSE53624 | CAPN9 | 10753 | 12061 | -0.7105 | 0.0003 | |
| GSE63941 | CAPN9 | 10753 | 208063_s_at | 0.4041 | 0.5887 | |
| GSE77861 | CAPN9 | 10753 | 210641_at | 0.0513 | 0.6836 | |
| TCGA | CAPN9 | 10753 | RNAseq | -4.1769 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CAPN9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPN9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPN9 | 10753 | 11 | 0 | 19 | |
| GSE20123 | CAPN9 | 10753 | 11 | 0 | 19 | |
| GSE43470 | CAPN9 | 10753 | 8 | 1 | 34 | |
| GSE46452 | CAPN9 | 10753 | 4 | 2 | 53 | |
| GSE47630 | CAPN9 | 10753 | 15 | 0 | 25 | |
| GSE54993 | CAPN9 | 10753 | 0 | 6 | 64 | |
| GSE54994 | CAPN9 | 10753 | 17 | 0 | 36 | |
| GSE60625 | CAPN9 | 10753 | 0 | 0 | 11 | |
| GSE74703 | CAPN9 | 10753 | 8 | 1 | 27 | |
| GSE74704 | CAPN9 | 10753 | 5 | 0 | 15 | |
| TCGA | CAPN9 | 10753 | 45 | 3 | 48 |
Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.
Somatic mutations of CAPN9:
Generating mutation plots.
Highly correlated genes for CAPN9:
Showing top 20/425 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPN9 | MS4A8 | 0.765889 | 3 | 0 | 3 |
| CAPN9 | ATP4A | 0.692439 | 5 | 0 | 4 |
| CAPN9 | CPA2 | 0.691796 | 6 | 0 | 6 |
| CAPN9 | TFF1 | 0.689981 | 7 | 0 | 6 |
| CAPN9 | NCR2 | 0.67876 | 3 | 0 | 3 |
| CAPN9 | SLC44A4 | 0.678297 | 8 | 0 | 7 |
| CAPN9 | GFRA4 | 0.671713 | 4 | 0 | 4 |
| CAPN9 | OBSL1 | 0.6648 | 3 | 0 | 3 |
| CAPN9 | HGF | 0.662748 | 3 | 0 | 3 |
| CAPN9 | DUSP21 | 0.661936 | 3 | 0 | 3 |
| CAPN9 | FBP2 | 0.659351 | 4 | 0 | 3 |
| CAPN9 | BTN1A1 | 0.656847 | 4 | 0 | 4 |
| CAPN9 | FOLH1 | 0.654037 | 3 | 0 | 3 |
| CAPN9 | SLC5A7 | 0.651685 | 3 | 0 | 3 |
| CAPN9 | NKX3-1 | 0.649139 | 5 | 0 | 4 |
| CAPN9 | TFF2 | 0.648221 | 8 | 0 | 6 |
| CAPN9 | FUT9 | 0.647562 | 5 | 0 | 5 |
| CAPN9 | EPS8L3 | 0.646853 | 6 | 0 | 6 |
| CAPN9 | SULT1C2 | 0.646521 | 4 | 0 | 4 |
| CAPN9 | SLC12A9 | 0.645966 | 3 | 0 | 3 |
For details and further investigation, click here
