| Full name: ADAM like decysin 1 | Alias Symbol: M12.219 | ||
| Type: protein-coding gene | Cytoband: 8p21.2 | ||
| Entrez ID: 27299 | HGNC ID: HGNC:16299 | Ensembl Gene: ENSG00000134028 | OMIM ID: 606393 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ADAMDEC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMDEC1 | 27299 | 206134_at | 1.1655 | 0.6398 | |
| GSE20347 | ADAMDEC1 | 27299 | 206134_at | 1.0775 | 0.0010 | |
| GSE23400 | ADAMDEC1 | 27299 | 206134_at | 0.5564 | 0.0000 | |
| GSE26886 | ADAMDEC1 | 27299 | 206134_at | -0.0190 | 0.9623 | |
| GSE29001 | ADAMDEC1 | 27299 | 206134_at | 0.8751 | 0.0838 | |
| GSE38129 | ADAMDEC1 | 27299 | 206134_at | 1.5396 | 0.0001 | |
| GSE45670 | ADAMDEC1 | 27299 | 206134_at | 1.6356 | 0.0030 | |
| GSE53622 | ADAMDEC1 | 27299 | 58835 | 1.9756 | 0.0000 | |
| GSE53624 | ADAMDEC1 | 27299 | 58835 | 1.4995 | 0.0000 | |
| GSE63941 | ADAMDEC1 | 27299 | 206134_at | -0.7254 | 0.0117 | |
| GSE77861 | ADAMDEC1 | 27299 | 206134_at | 0.3045 | 0.1905 | |
| GSE97050 | ADAMDEC1 | 27299 | A_33_P3390172 | 0.4930 | 0.0885 | |
| SRP008496 | ADAMDEC1 | 27299 | RNAseq | 3.0236 | 0.0039 | |
| SRP133303 | ADAMDEC1 | 27299 | RNAseq | 1.9450 | 0.0001 | |
| TCGA | ADAMDEC1 | 27299 | RNAseq | 1.9094 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by ADAMDEC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMDEC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMDEC1 | 27299 | 4 | 12 | 14 | |
| GSE20123 | ADAMDEC1 | 27299 | 4 | 12 | 14 | |
| GSE43470 | ADAMDEC1 | 27299 | 4 | 7 | 32 | |
| GSE46452 | ADAMDEC1 | 27299 | 13 | 13 | 33 | |
| GSE47630 | ADAMDEC1 | 27299 | 10 | 8 | 22 | |
| GSE54993 | ADAMDEC1 | 27299 | 2 | 14 | 54 | |
| GSE54994 | ADAMDEC1 | 27299 | 8 | 18 | 27 | |
| GSE60625 | ADAMDEC1 | 27299 | 3 | 0 | 8 | |
| GSE74703 | ADAMDEC1 | 27299 | 4 | 6 | 26 | |
| GSE74704 | ADAMDEC1 | 27299 | 3 | 8 | 9 | |
| TCGA | ADAMDEC1 | 27299 | 15 | 43 | 38 |
Total number of gains: 70; Total number of losses: 141; Total Number of normals: 277.
Somatic mutations of ADAMDEC1:
Generating mutation plots.
Highly correlated genes for ADAMDEC1:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMDEC1 | CERKL | 0.77869 | 3 | 0 | 3 |
| ADAMDEC1 | WDR81 | 0.764749 | 3 | 0 | 3 |
| ADAMDEC1 | LTF | 0.757877 | 3 | 0 | 3 |
| ADAMDEC1 | HAVCR2 | 0.755823 | 5 | 0 | 5 |
| ADAMDEC1 | CCND3 | 0.753169 | 4 | 0 | 4 |
| ADAMDEC1 | FCGR3A | 0.751025 | 3 | 0 | 3 |
| ADAMDEC1 | PIK3R5 | 0.731937 | 4 | 0 | 4 |
| ADAMDEC1 | CCL19 | 0.724422 | 3 | 0 | 3 |
| ADAMDEC1 | SLAMF8 | 0.714266 | 10 | 0 | 9 |
| ADAMDEC1 | TFEC | 0.712682 | 11 | 0 | 9 |
| ADAMDEC1 | C16orf54 | 0.71192 | 4 | 0 | 4 |
| ADAMDEC1 | GPR141 | 0.711798 | 3 | 0 | 3 |
| ADAMDEC1 | SUCNR1 | 0.710825 | 5 | 0 | 5 |
| ADAMDEC1 | FAM160B1 | 0.71021 | 3 | 0 | 3 |
| ADAMDEC1 | PILRA | 0.706291 | 5 | 0 | 4 |
| ADAMDEC1 | CD86 | 0.706048 | 8 | 0 | 7 |
| ADAMDEC1 | MAPRE1 | 0.70087 | 3 | 0 | 3 |
| ADAMDEC1 | CD53 | 0.700232 | 10 | 0 | 9 |
| ADAMDEC1 | C1QB | 0.698456 | 12 | 0 | 11 |
| ADAMDEC1 | LRRC8C | 0.6934 | 3 | 0 | 3 |
For details and further investigation, click here
