| Full name: GEM interacting protein | Alias Symbol: ARHGAP46 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 51291 | HGNC ID: HGNC:24852 | Ensembl Gene: ENSG00000089639 | OMIM ID: 609694 |
| Drug and gene relationship at DGIdb | |||
Expression of GMIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GMIP | 51291 | 218913_s_at | 0.4871 | 0.2838 | |
| GSE20347 | GMIP | 51291 | 218913_s_at | -0.0925 | 0.5248 | |
| GSE23400 | GMIP | 51291 | 218913_s_at | 0.0594 | 0.2471 | |
| GSE26886 | GMIP | 51291 | 218913_s_at | 0.0320 | 0.8666 | |
| GSE29001 | GMIP | 51291 | 218913_s_at | 0.0631 | 0.6443 | |
| GSE38129 | GMIP | 51291 | 218913_s_at | -0.0424 | 0.7768 | |
| GSE45670 | GMIP | 51291 | 218913_s_at | 0.2310 | 0.0228 | |
| GSE53622 | GMIP | 51291 | 61542 | 0.0769 | 0.2348 | |
| GSE53624 | GMIP | 51291 | 61542 | -0.0381 | 0.4436 | |
| GSE63941 | GMIP | 51291 | 218913_s_at | -0.2221 | 0.5857 | |
| GSE77861 | GMIP | 51291 | 222782_s_at | -0.1231 | 0.2696 | |
| GSE97050 | GMIP | 51291 | A_23_P56228 | 0.4203 | 0.2057 | |
| SRP007169 | GMIP | 51291 | RNAseq | -1.4788 | 0.0062 | |
| SRP008496 | GMIP | 51291 | RNAseq | -1.3782 | 0.0000 | |
| SRP064894 | GMIP | 51291 | RNAseq | 0.2693 | 0.0640 | |
| SRP133303 | GMIP | 51291 | RNAseq | -0.1759 | 0.2458 | |
| SRP159526 | GMIP | 51291 | RNAseq | -0.7914 | 0.0091 | |
| SRP193095 | GMIP | 51291 | RNAseq | -0.0795 | 0.7412 | |
| SRP219564 | GMIP | 51291 | RNAseq | -0.0530 | 0.9152 | |
| TCGA | GMIP | 51291 | RNAseq | -0.0259 | 0.6900 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GMIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GMIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GMIP | 51291 | 4 | 5 | 21 | |
| GSE20123 | GMIP | 51291 | 3 | 3 | 24 | |
| GSE43470 | GMIP | 51291 | 2 | 5 | 36 | |
| GSE46452 | GMIP | 51291 | 47 | 1 | 11 | |
| GSE47630 | GMIP | 51291 | 5 | 8 | 27 | |
| GSE54993 | GMIP | 51291 | 16 | 4 | 50 | |
| GSE54994 | GMIP | 51291 | 6 | 13 | 34 | |
| GSE60625 | GMIP | 51291 | 9 | 0 | 2 | |
| GSE74703 | GMIP | 51291 | 2 | 3 | 31 | |
| GSE74704 | GMIP | 51291 | 0 | 3 | 17 | |
| TCGA | GMIP | 51291 | 16 | 10 | 70 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of GMIP:
Generating mutation plots.
Highly correlated genes for GMIP:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GMIP | TLR6 | 0.793825 | 3 | 0 | 3 |
| GMIP | BCL6B | 0.731064 | 3 | 0 | 3 |
| GMIP | CPNE7 | 0.718468 | 3 | 0 | 3 |
| GMIP | CD70 | 0.702084 | 3 | 0 | 3 |
| GMIP | ANKLE1 | 0.689804 | 3 | 0 | 3 |
| GMIP | MBD6 | 0.68872 | 4 | 0 | 3 |
| GMIP | C7orf61 | 0.688381 | 3 | 0 | 3 |
| GMIP | ZAN | 0.687061 | 3 | 0 | 3 |
| GMIP | IGLL1 | 0.68537 | 3 | 0 | 3 |
| GMIP | ZBTB46 | 0.671081 | 3 | 0 | 3 |
| GMIP | SLC6A18 | 0.667539 | 3 | 0 | 3 |
| GMIP | F11R | 0.658558 | 3 | 0 | 3 |
| GMIP | ICAM3 | 0.651213 | 6 | 0 | 6 |
| GMIP | FERMT3 | 0.642523 | 5 | 0 | 3 |
| GMIP | CEMP1 | 0.635719 | 3 | 0 | 3 |
| GMIP | ABI3 | 0.633978 | 5 | 0 | 3 |
| GMIP | GNL1 | 0.628939 | 3 | 0 | 3 |
| GMIP | LRRC45 | 0.620906 | 3 | 0 | 3 |
| GMIP | C11orf94 | 0.619809 | 3 | 0 | 3 |
| GMIP | TMEM104 | 0.606938 | 4 | 0 | 3 |
For details and further investigation, click here
