| Full name: BAF chromatin remodeling complex subunit BCL7A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 605 | HGNC ID: HGNC:1004 | Ensembl Gene: ENSG00000110987 | OMIM ID: 601406 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL7A | 605 | 203795_s_at | 0.9911 | 0.0377 | |
| GSE20347 | BCL7A | 605 | 203796_s_at | 0.5973 | 0.0000 | |
| GSE23400 | BCL7A | 605 | 203795_s_at | 0.2747 | 0.0000 | |
| GSE26886 | BCL7A | 605 | 203796_s_at | 1.1059 | 0.0000 | |
| GSE29001 | BCL7A | 605 | 203796_s_at | 0.8426 | 0.0018 | |
| GSE38129 | BCL7A | 605 | 203796_s_at | 0.6758 | 0.0000 | |
| GSE45670 | BCL7A | 605 | 203796_s_at | 0.7327 | 0.0003 | |
| GSE53622 | BCL7A | 605 | 106450 | 1.3416 | 0.0000 | |
| GSE53624 | BCL7A | 605 | 106450 | 1.3788 | 0.0000 | |
| GSE63941 | BCL7A | 605 | 203795_s_at | 2.1634 | 0.0000 | |
| GSE77861 | BCL7A | 605 | 203795_s_at | 0.3188 | 0.0508 | |
| GSE97050 | BCL7A | 605 | A_24_P203056 | 0.3070 | 0.2926 | |
| SRP007169 | BCL7A | 605 | RNAseq | 1.8894 | 0.0001 | |
| SRP008496 | BCL7A | 605 | RNAseq | 1.6588 | 0.0000 | |
| SRP064894 | BCL7A | 605 | RNAseq | 0.7789 | 0.0002 | |
| SRP133303 | BCL7A | 605 | RNAseq | 1.0251 | 0.0000 | |
| SRP159526 | BCL7A | 605 | RNAseq | 1.7379 | 0.0000 | |
| SRP193095 | BCL7A | 605 | RNAseq | 1.4345 | 0.0000 | |
| SRP219564 | BCL7A | 605 | RNAseq | 0.8828 | 0.0067 | |
| TCGA | BCL7A | 605 | RNAseq | 0.3251 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by BCL7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL7A | 605 | 5 | 4 | 21 | |
| GSE20123 | BCL7A | 605 | 5 | 4 | 21 | |
| GSE43470 | BCL7A | 605 | 2 | 2 | 39 | |
| GSE46452 | BCL7A | 605 | 9 | 1 | 49 | |
| GSE47630 | BCL7A | 605 | 9 | 3 | 28 | |
| GSE54993 | BCL7A | 605 | 0 | 5 | 65 | |
| GSE54994 | BCL7A | 605 | 5 | 7 | 41 | |
| GSE60625 | BCL7A | 605 | 0 | 0 | 11 | |
| GSE74703 | BCL7A | 605 | 2 | 1 | 33 | |
| GSE74704 | BCL7A | 605 | 4 | 2 | 14 | |
| TCGA | BCL7A | 605 | 21 | 10 | 65 |
Total number of gains: 62; Total number of losses: 39; Total Number of normals: 387.
Somatic mutations of BCL7A:
Generating mutation plots.
Highly correlated genes for BCL7A:
Showing top 20/1807 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL7A | ZNF707 | 0.807566 | 3 | 0 | 3 |
| BCL7A | PTCD1 | 0.772041 | 3 | 0 | 3 |
| BCL7A | SLC39A3 | 0.771566 | 4 | 0 | 4 |
| BCL7A | CERS5 | 0.747728 | 5 | 0 | 5 |
| BCL7A | RNF4 | 0.746171 | 3 | 0 | 3 |
| BCL7A | RAB34 | 0.742092 | 3 | 0 | 3 |
| BCL7A | ZBTB8A | 0.737531 | 3 | 0 | 3 |
| BCL7A | A4GALT | 0.734627 | 3 | 0 | 3 |
| BCL7A | TP53I13 | 0.731419 | 7 | 0 | 6 |
| BCL7A | UCK2 | 0.731258 | 3 | 0 | 3 |
| BCL7A | FYN | 0.729397 | 4 | 0 | 4 |
| BCL7A | FAR2 | 0.728496 | 3 | 0 | 3 |
| BCL7A | TEAD2 | 0.727011 | 6 | 0 | 6 |
| BCL7A | PPP5C | 0.726394 | 5 | 0 | 5 |
| BCL7A | SIX4 | 0.723085 | 8 | 0 | 7 |
| BCL7A | QSOX2 | 0.721433 | 6 | 0 | 6 |
| BCL7A | CLPTM1L | 0.717774 | 6 | 0 | 6 |
| BCL7A | WDR5 | 0.714374 | 7 | 0 | 7 |
| BCL7A | SORL1 | 0.714291 | 4 | 0 | 3 |
| BCL7A | KRTCAP2 | 0.712482 | 5 | 0 | 5 |
For details and further investigation, click here
