| Full name: fatty acyl-CoA reductase 2 | Alias Symbol: FLJ10462|SDR10E2 | ||
| Type: protein-coding gene | Cytoband: 12p11.22 | ||
| Entrez ID: 55711 | HGNC ID: HGNC:25531 | Ensembl Gene: ENSG00000064763 | OMIM ID: 616156 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAR2 | 55711 | 220615_s_at | -0.0494 | 0.9797 | |
| GSE20347 | FAR2 | 55711 | 220615_s_at | 0.3224 | 0.0268 | |
| GSE23400 | FAR2 | 55711 | 220615_s_at | 0.0736 | 0.2789 | |
| GSE26886 | FAR2 | 55711 | 220615_s_at | 1.5621 | 0.0037 | |
| GSE29001 | FAR2 | 55711 | 220615_s_at | 1.1995 | 0.0171 | |
| GSE38129 | FAR2 | 55711 | 220615_s_at | 0.2413 | 0.3124 | |
| GSE45670 | FAR2 | 55711 | 220615_s_at | -0.1172 | 0.8591 | |
| GSE53622 | FAR2 | 55711 | 48219 | -0.1522 | 0.2659 | |
| GSE53624 | FAR2 | 55711 | 48219 | 0.3400 | 0.0048 | |
| GSE63941 | FAR2 | 55711 | 220615_s_at | -1.2413 | 0.3562 | |
| GSE77861 | FAR2 | 55711 | 220615_s_at | 0.2065 | 0.2969 | |
| GSE97050 | FAR2 | 55711 | A_23_P150903 | -0.3995 | 0.1581 | |
| SRP007169 | FAR2 | 55711 | RNAseq | 1.1786 | 0.0595 | |
| SRP008496 | FAR2 | 55711 | RNAseq | 0.9401 | 0.0426 | |
| SRP064894 | FAR2 | 55711 | RNAseq | 0.3028 | 0.2889 | |
| SRP133303 | FAR2 | 55711 | RNAseq | -0.0837 | 0.7200 | |
| SRP159526 | FAR2 | 55711 | RNAseq | 0.1027 | 0.7681 | |
| SRP193095 | FAR2 | 55711 | RNAseq | 0.1366 | 0.5655 | |
| SRP219564 | FAR2 | 55711 | RNAseq | 0.0353 | 0.9376 | |
| TCGA | FAR2 | 55711 | RNAseq | -0.0016 | 0.9933 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAR2 | 55711 | 9 | 1 | 20 | |
| GSE20123 | FAR2 | 55711 | 9 | 1 | 20 | |
| GSE43470 | FAR2 | 55711 | 8 | 3 | 32 | |
| GSE46452 | FAR2 | 55711 | 10 | 1 | 48 | |
| GSE47630 | FAR2 | 55711 | 13 | 0 | 27 | |
| GSE54993 | FAR2 | 55711 | 0 | 9 | 61 | |
| GSE54994 | FAR2 | 55711 | 9 | 2 | 42 | |
| GSE60625 | FAR2 | 55711 | 0 | 1 | 10 | |
| GSE74703 | FAR2 | 55711 | 7 | 2 | 27 | |
| GSE74704 | FAR2 | 55711 | 5 | 1 | 14 | |
| TCGA | FAR2 | 55711 | 41 | 7 | 48 |
Total number of gains: 111; Total number of losses: 28; Total Number of normals: 349.
Somatic mutations of FAR2:
Generating mutation plots.
Highly correlated genes for FAR2:
Showing top 20/1063 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAR2 | FAM86C1 | 0.795285 | 3 | 0 | 3 |
| FAR2 | RIMKLB | 0.78523 | 3 | 0 | 3 |
| FAR2 | RNF4 | 0.754899 | 3 | 0 | 3 |
| FAR2 | SCAI | 0.754315 | 4 | 0 | 3 |
| FAR2 | CBLL1 | 0.751334 | 3 | 0 | 3 |
| FAR2 | ZNF703 | 0.742263 | 4 | 0 | 4 |
| FAR2 | MLLT3 | 0.740479 | 3 | 0 | 3 |
| FAR2 | COA5 | 0.732099 | 3 | 0 | 3 |
| FAR2 | BCL7A | 0.728496 | 3 | 0 | 3 |
| FAR2 | USP28 | 0.7244 | 4 | 0 | 4 |
| FAR2 | RNF121 | 0.707721 | 3 | 0 | 3 |
| FAR2 | GPR158 | 0.706872 | 3 | 0 | 3 |
| FAR2 | PLOD1 | 0.705737 | 6 | 0 | 6 |
| FAR2 | TRIM45 | 0.70538 | 3 | 0 | 3 |
| FAR2 | ICK | 0.702883 | 3 | 0 | 3 |
| FAR2 | OSR1 | 0.698716 | 3 | 0 | 3 |
| FAR2 | RPS27 | 0.69819 | 3 | 0 | 3 |
| FAR2 | MYADM | 0.698011 | 4 | 0 | 3 |
| FAR2 | SLC38A6 | 0.695265 | 3 | 0 | 3 |
| FAR2 | PHC2 | 0.694885 | 8 | 0 | 7 |
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