| Full name: BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | Alias Symbol: Hs.6719|BCS|h-BCS|BJS | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 617 | HGNC ID: HGNC:1020 | Ensembl Gene: ENSG00000074582 | OMIM ID: 603647 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of BCS1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCS1L | 617 | 207618_s_at | -0.0985 | 0.8420 | |
| GSE20347 | BCS1L | 617 | 207618_s_at | -0.1864 | 0.1622 | |
| GSE23400 | BCS1L | 617 | 207618_s_at | 0.0274 | 0.5991 | |
| GSE26886 | BCS1L | 617 | 207618_s_at | -0.4814 | 0.0072 | |
| GSE29001 | BCS1L | 617 | 207618_s_at | 0.0103 | 0.9785 | |
| GSE38129 | BCS1L | 617 | 207618_s_at | -0.1932 | 0.0920 | |
| GSE45670 | BCS1L | 617 | 207618_s_at | -0.0253 | 0.8710 | |
| GSE53622 | BCS1L | 617 | 25728 | 0.0970 | 0.2567 | |
| GSE53624 | BCS1L | 617 | 25728 | 0.1016 | 0.1409 | |
| GSE63941 | BCS1L | 617 | 207618_s_at | 0.4697 | 0.2331 | |
| GSE77861 | BCS1L | 617 | 207618_s_at | -0.1194 | 0.5275 | |
| GSE97050 | BCS1L | 617 | A_23_P154086 | 0.1745 | 0.5508 | |
| SRP007169 | BCS1L | 617 | RNAseq | -0.2888 | 0.6325 | |
| SRP008496 | BCS1L | 617 | RNAseq | -0.2531 | 0.4749 | |
| SRP064894 | BCS1L | 617 | RNAseq | 0.2341 | 0.3573 | |
| SRP133303 | BCS1L | 617 | RNAseq | 0.0104 | 0.9432 | |
| SRP159526 | BCS1L | 617 | RNAseq | 0.0552 | 0.8847 | |
| SRP193095 | BCS1L | 617 | RNAseq | -0.0634 | 0.6074 | |
| SRP219564 | BCS1L | 617 | RNAseq | -0.0500 | 0.8822 | |
| TCGA | BCS1L | 617 | RNAseq | 0.0370 | 0.5530 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BCS1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCS1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCS1L | 617 | 1 | 14 | 15 | |
| GSE20123 | BCS1L | 617 | 1 | 13 | 16 | |
| GSE43470 | BCS1L | 617 | 1 | 7 | 35 | |
| GSE46452 | BCS1L | 617 | 0 | 5 | 54 | |
| GSE47630 | BCS1L | 617 | 4 | 5 | 31 | |
| GSE54993 | BCS1L | 617 | 1 | 2 | 67 | |
| GSE54994 | BCS1L | 617 | 8 | 10 | 35 | |
| GSE60625 | BCS1L | 617 | 0 | 3 | 8 | |
| GSE74703 | BCS1L | 617 | 1 | 5 | 30 | |
| GSE74704 | BCS1L | 617 | 1 | 7 | 12 | |
| TCGA | BCS1L | 617 | 11 | 27 | 58 |
Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.
Somatic mutations of BCS1L:
Generating mutation plots.
Highly correlated genes for BCS1L:
Showing top 20/253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCS1L | DAAM1 | 0.792397 | 3 | 0 | 3 |
| BCS1L | GLOD4 | 0.770197 | 3 | 0 | 3 |
| BCS1L | TRAPPC6B | 0.765549 | 3 | 0 | 3 |
| BCS1L | SGMS2 | 0.749969 | 3 | 0 | 3 |
| BCS1L | EEA1 | 0.742235 | 3 | 0 | 3 |
| BCS1L | CAPN2 | 0.740524 | 3 | 0 | 3 |
| BCS1L | C21orf91 | 0.735198 | 3 | 0 | 3 |
| BCS1L | EIF4E | 0.729439 | 3 | 0 | 3 |
| BCS1L | WLS | 0.727572 | 3 | 0 | 3 |
| BCS1L | ZFAND6 | 0.725229 | 3 | 0 | 3 |
| BCS1L | RRN3 | 0.722748 | 4 | 0 | 3 |
| BCS1L | ARF6 | 0.721058 | 3 | 0 | 3 |
| BCS1L | SYTL4 | 0.711242 | 3 | 0 | 3 |
| BCS1L | NHEJ1 | 0.704983 | 3 | 0 | 3 |
| BCS1L | CHID1 | 0.703084 | 3 | 0 | 3 |
| BCS1L | DNAJB14 | 0.702357 | 3 | 0 | 3 |
| BCS1L | ESYT2 | 0.702012 | 3 | 0 | 3 |
| BCS1L | SLC38A1 | 0.694014 | 3 | 0 | 3 |
| BCS1L | MAP4K5 | 0.693532 | 4 | 0 | 3 |
| BCS1L | TMEM41B | 0.69322 | 3 | 0 | 3 |
For details and further investigation, click here
