| Full name: dishevelled associated activator of morphogenesis 1 | Alias Symbol: KIAA0666 | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 23002 | HGNC ID: HGNC:18142 | Ensembl Gene: ENSG00000100592 | OMIM ID: 606626 |
| Drug and gene relationship at DGIdb | |||
DAAM1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04310 | Wnt signaling pathway |
Expression of DAAM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAAM1 | 23002 | 216060_s_at | -0.8180 | 0.2423 | |
| GSE20347 | DAAM1 | 23002 | 216060_s_at | -1.1250 | 0.0001 | |
| GSE23400 | DAAM1 | 23002 | 216060_s_at | -0.6643 | 0.0000 | |
| GSE26886 | DAAM1 | 23002 | 216060_s_at | -1.2070 | 0.0001 | |
| GSE29001 | DAAM1 | 23002 | 216060_s_at | -0.3054 | 0.4443 | |
| GSE38129 | DAAM1 | 23002 | 216060_s_at | -1.1261 | 0.0000 | |
| GSE45670 | DAAM1 | 23002 | 226666_at | -0.5207 | 0.0083 | |
| GSE53622 | DAAM1 | 23002 | 83966 | -0.6692 | 0.0000 | |
| GSE53624 | DAAM1 | 23002 | 83966 | -0.7695 | 0.0000 | |
| GSE63941 | DAAM1 | 23002 | 216060_s_at | 0.4644 | 0.4355 | |
| GSE77861 | DAAM1 | 23002 | 216060_s_at | -0.6928 | 0.0542 | |
| GSE97050 | DAAM1 | 23002 | A_23_P54116 | -0.4729 | 0.1923 | |
| SRP007169 | DAAM1 | 23002 | RNAseq | -1.3870 | 0.0003 | |
| SRP008496 | DAAM1 | 23002 | RNAseq | -1.4098 | 0.0000 | |
| SRP064894 | DAAM1 | 23002 | RNAseq | -0.7459 | 0.0012 | |
| SRP133303 | DAAM1 | 23002 | RNAseq | -0.7274 | 0.0019 | |
| SRP159526 | DAAM1 | 23002 | RNAseq | -1.8725 | 0.0000 | |
| SRP193095 | DAAM1 | 23002 | RNAseq | -0.8596 | 0.0000 | |
| SRP219564 | DAAM1 | 23002 | RNAseq | -0.7694 | 0.0828 | |
| TCGA | DAAM1 | 23002 | RNAseq | -0.0943 | 0.2707 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by DAAM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAAM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAAM1 | 23002 | 8 | 3 | 19 | |
| GSE20123 | DAAM1 | 23002 | 7 | 3 | 20 | |
| GSE43470 | DAAM1 | 23002 | 8 | 2 | 33 | |
| GSE46452 | DAAM1 | 23002 | 16 | 3 | 40 | |
| GSE47630 | DAAM1 | 23002 | 11 | 9 | 20 | |
| GSE54993 | DAAM1 | 23002 | 3 | 8 | 59 | |
| GSE54994 | DAAM1 | 23002 | 19 | 4 | 30 | |
| GSE60625 | DAAM1 | 23002 | 0 | 2 | 9 | |
| GSE74703 | DAAM1 | 23002 | 7 | 2 | 27 | |
| GSE74704 | DAAM1 | 23002 | 3 | 2 | 15 | |
| TCGA | DAAM1 | 23002 | 32 | 14 | 50 |
Total number of gains: 114; Total number of losses: 52; Total Number of normals: 322.
Somatic mutations of DAAM1:
Generating mutation plots.
Highly correlated genes for DAAM1:
Showing top 20/1023 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAAM1 | BCS1L | 0.792397 | 3 | 0 | 3 |
| DAAM1 | ZNF70 | 0.772364 | 3 | 0 | 3 |
| DAAM1 | IMPACT | 0.770916 | 3 | 0 | 3 |
| DAAM1 | ECD | 0.757355 | 3 | 0 | 3 |
| DAAM1 | THUMPD3 | 0.749514 | 4 | 0 | 4 |
| DAAM1 | MRPL46 | 0.738893 | 3 | 0 | 3 |
| DAAM1 | HIPK3 | 0.734746 | 3 | 0 | 3 |
| DAAM1 | EIF4E2 | 0.725062 | 3 | 0 | 3 |
| DAAM1 | RBX1 | 0.720798 | 3 | 0 | 3 |
| DAAM1 | PRPF38A | 0.716312 | 4 | 0 | 4 |
| DAAM1 | STYX | 0.706428 | 5 | 0 | 5 |
| DAAM1 | LACTB | 0.701169 | 3 | 0 | 3 |
| DAAM1 | NDUFB3 | 0.698111 | 3 | 0 | 3 |
| DAAM1 | ANKRD37 | 0.696286 | 5 | 0 | 5 |
| DAAM1 | CTTNBP2NL | 0.690609 | 7 | 0 | 7 |
| DAAM1 | SPIN4 | 0.689144 | 3 | 0 | 3 |
| DAAM1 | BARD1 | 0.689117 | 4 | 0 | 3 |
| DAAM1 | PDLIM2 | 0.687419 | 8 | 0 | 8 |
| DAAM1 | MOB3C | 0.687288 | 3 | 0 | 3 |
| DAAM1 | OR14J1 | 0.68493 | 3 | 0 | 3 |
For details and further investigation, click here
