| Full name: solute carrier family 38 member 1 | Alias Symbol: ATA1|NAT2|SAT1 | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 81539 | HGNC ID: HGNC:13447 | Ensembl Gene: ENSG00000111371 | OMIM ID: 608490 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC38A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC38A1 | 81539 | 224579_at | 0.0152 | 0.9898 | |
| GSE20347 | SLC38A1 | 81539 | 218237_s_at | 0.2680 | 0.4078 | |
| GSE23400 | SLC38A1 | 81539 | 218237_s_at | 0.4046 | 0.0004 | |
| GSE26886 | SLC38A1 | 81539 | 218237_s_at | -0.0162 | 0.9537 | |
| GSE29001 | SLC38A1 | 81539 | 218237_s_at | 0.7418 | 0.0229 | |
| GSE38129 | SLC38A1 | 81539 | 218237_s_at | 0.3161 | 0.2079 | |
| GSE45670 | SLC38A1 | 81539 | 224579_at | 0.1765 | 0.3693 | |
| GSE53622 | SLC38A1 | 81539 | 83548 | 0.3047 | 0.0008 | |
| GSE53624 | SLC38A1 | 81539 | 83548 | 0.5347 | 0.0000 | |
| GSE63941 | SLC38A1 | 81539 | 218237_s_at | 1.0270 | 0.0862 | |
| GSE77861 | SLC38A1 | 81539 | 224579_at | 0.9465 | 0.0019 | |
| GSE97050 | SLC38A1 | 81539 | A_23_P363399 | -0.0960 | 0.8624 | |
| SRP007169 | SLC38A1 | 81539 | RNAseq | 1.9064 | 0.0002 | |
| SRP008496 | SLC38A1 | 81539 | RNAseq | 1.2006 | 0.0051 | |
| SRP064894 | SLC38A1 | 81539 | RNAseq | 0.2425 | 0.3088 | |
| SRP133303 | SLC38A1 | 81539 | RNAseq | 0.5357 | 0.0013 | |
| SRP159526 | SLC38A1 | 81539 | RNAseq | -0.3962 | 0.1124 | |
| SRP193095 | SLC38A1 | 81539 | RNAseq | 0.1926 | 0.0690 | |
| SRP219564 | SLC38A1 | 81539 | RNAseq | 0.0438 | 0.9064 | |
| TCGA | SLC38A1 | 81539 | RNAseq | 0.1185 | 0.0328 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC38A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC38A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC38A1 | 81539 | 7 | 1 | 22 | |
| GSE20123 | SLC38A1 | 81539 | 7 | 1 | 22 | |
| GSE43470 | SLC38A1 | 81539 | 3 | 1 | 39 | |
| GSE46452 | SLC38A1 | 81539 | 8 | 1 | 50 | |
| GSE47630 | SLC38A1 | 81539 | 11 | 2 | 27 | |
| GSE54993 | SLC38A1 | 81539 | 0 | 5 | 65 | |
| GSE54994 | SLC38A1 | 81539 | 7 | 1 | 45 | |
| GSE60625 | SLC38A1 | 81539 | 0 | 0 | 11 | |
| GSE74703 | SLC38A1 | 81539 | 3 | 1 | 32 | |
| GSE74704 | SLC38A1 | 81539 | 3 | 1 | 16 | |
| TCGA | SLC38A1 | 81539 | 16 | 13 | 67 |
Total number of gains: 65; Total number of losses: 27; Total Number of normals: 396.
Somatic mutations of SLC38A1:
Generating mutation plots.
Highly correlated genes for SLC38A1:
Showing top 20/521 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC38A1 | ZNF398 | 0.784816 | 3 | 0 | 3 |
| SLC38A1 | USP37 | 0.771314 | 3 | 0 | 3 |
| SLC38A1 | CEP95 | 0.769669 | 3 | 0 | 3 |
| SLC38A1 | ZFPL1 | 0.742252 | 3 | 0 | 3 |
| SLC38A1 | PLEKHM3 | 0.728621 | 3 | 0 | 3 |
| SLC38A1 | COX6A1 | 0.727447 | 3 | 0 | 3 |
| SLC38A1 | CDKN2D | 0.71043 | 3 | 0 | 3 |
| SLC38A1 | ZNF740 | 0.699866 | 3 | 0 | 3 |
| SLC38A1 | TUBE1 | 0.699214 | 3 | 0 | 3 |
| SLC38A1 | BABAM1 | 0.695855 | 4 | 0 | 4 |
| SLC38A1 | NDUFV1 | 0.695807 | 3 | 0 | 3 |
| SLC38A1 | PMF1 | 0.695105 | 3 | 0 | 3 |
| SLC38A1 | BCS1L | 0.694014 | 3 | 0 | 3 |
| SLC38A1 | MED26 | 0.693495 | 3 | 0 | 3 |
| SLC38A1 | ALG10 | 0.69319 | 4 | 0 | 3 |
| SLC38A1 | ANKRD40 | 0.692787 | 3 | 0 | 3 |
| SLC38A1 | DNAJC21 | 0.690397 | 3 | 0 | 3 |
| SLC38A1 | C1orf115 | 0.681817 | 3 | 0 | 3 |
| SLC38A1 | FAM169A | 0.680178 | 4 | 0 | 4 |
| SLC38A1 | ZCRB1 | 0.679914 | 4 | 0 | 4 |
For details and further investigation, click here
