| Full name: 3-hydroxybutyrate dehydrogenase 1 | Alias Symbol: SDR9C1 | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 622 | HGNC ID: HGNC:1027 | Ensembl Gene: ENSG00000161267 | OMIM ID: 603063 |
| Drug and gene relationship at DGIdb | |||
Expression of BDH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BDH1 | 622 | 211715_s_at | -0.0730 | 0.9218 | |
| GSE20347 | BDH1 | 622 | 211715_s_at | -0.4381 | 0.0492 | |
| GSE23400 | BDH1 | 622 | 211715_s_at | -0.3109 | 0.0129 | |
| GSE26886 | BDH1 | 622 | 211715_s_at | -0.9077 | 0.0030 | |
| GSE29001 | BDH1 | 622 | 211715_s_at | -0.5493 | 0.0611 | |
| GSE38129 | BDH1 | 622 | 211715_s_at | -0.1887 | 0.4886 | |
| GSE45670 | BDH1 | 622 | 211715_s_at | 0.2392 | 0.4298 | |
| GSE53622 | BDH1 | 622 | 91957 | -0.7865 | 0.0000 | |
| GSE53624 | BDH1 | 622 | 91957 | -0.9885 | 0.0000 | |
| GSE63941 | BDH1 | 622 | 211715_s_at | 1.5529 | 0.0405 | |
| GSE77861 | BDH1 | 622 | 211715_s_at | -0.1970 | 0.5141 | |
| GSE97050 | BDH1 | 622 | A_33_P3252359 | -0.1192 | 0.7225 | |
| SRP007169 | BDH1 | 622 | RNAseq | -1.9424 | 0.0000 | |
| SRP008496 | BDH1 | 622 | RNAseq | -1.8150 | 0.0000 | |
| SRP064894 | BDH1 | 622 | RNAseq | -0.6440 | 0.0468 | |
| SRP133303 | BDH1 | 622 | RNAseq | -0.5996 | 0.0883 | |
| SRP159526 | BDH1 | 622 | RNAseq | -0.3690 | 0.3488 | |
| SRP193095 | BDH1 | 622 | RNAseq | -0.6963 | 0.0003 | |
| SRP219564 | BDH1 | 622 | RNAseq | -1.1195 | 0.0535 | |
| TCGA | BDH1 | 622 | RNAseq | 0.1156 | 0.2430 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by BDH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BDH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BDH1 | 622 | 23 | 0 | 7 | |
| GSE20123 | BDH1 | 622 | 23 | 0 | 7 | |
| GSE43470 | BDH1 | 622 | 21 | 0 | 22 | |
| GSE46452 | BDH1 | 622 | 20 | 1 | 38 | |
| GSE47630 | BDH1 | 622 | 27 | 2 | 11 | |
| GSE54993 | BDH1 | 622 | 1 | 22 | 47 | |
| GSE54994 | BDH1 | 622 | 41 | 0 | 12 | |
| GSE60625 | BDH1 | 622 | 0 | 6 | 5 | |
| GSE74703 | BDH1 | 622 | 19 | 0 | 17 | |
| GSE74704 | BDH1 | 622 | 14 | 0 | 6 | |
| TCGA | BDH1 | 622 | 77 | 0 | 19 |
Total number of gains: 266; Total number of losses: 31; Total Number of normals: 191.
Somatic mutations of BDH1:
Generating mutation plots.
Highly correlated genes for BDH1:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BDH1 | NCCRP1 | 0.740402 | 3 | 0 | 3 |
| BDH1 | RNF222 | 0.71259 | 3 | 0 | 3 |
| BDH1 | NOTO | 0.712498 | 3 | 0 | 3 |
| BDH1 | KPRP | 0.705287 | 3 | 0 | 3 |
| BDH1 | TMPRSS11A | 0.704727 | 3 | 0 | 3 |
| BDH1 | PHLDB3 | 0.697903 | 5 | 0 | 4 |
| BDH1 | C10orf99 | 0.694162 | 5 | 0 | 5 |
| BDH1 | OTOP3 | 0.688902 | 3 | 0 | 3 |
| BDH1 | SDCBP2 | 0.678396 | 4 | 0 | 4 |
| BDH1 | FAM163B | 0.67732 | 3 | 0 | 3 |
| BDH1 | MFSD2B | 0.670694 | 3 | 0 | 3 |
| BDH1 | TIGD3 | 0.669495 | 3 | 0 | 3 |
| BDH1 | GRHL3 | 0.669156 | 8 | 0 | 8 |
| BDH1 | TPRN | 0.667814 | 5 | 0 | 4 |
| BDH1 | SBSN | 0.667423 | 5 | 0 | 4 |
| BDH1 | VSIG10L | 0.659764 | 5 | 0 | 4 |
| BDH1 | ZNF770 | 0.655093 | 4 | 0 | 4 |
| BDH1 | NHLRC4 | 0.654564 | 3 | 0 | 3 |
| BDH1 | DEGS2 | 0.652525 | 5 | 0 | 4 |
| BDH1 | SPATA19 | 0.650927 | 4 | 0 | 3 |
For details and further investigation, click here
