| Full name: tigger transposable element derived 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 220359 | HGNC ID: HGNC:18334 | Ensembl Gene: ENSG00000173825 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TIGD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIGD3 | 220359 | 229789_at | 0.0049 | 0.9942 | |
| GSE26886 | TIGD3 | 220359 | 229789_at | 0.1269 | 0.4001 | |
| GSE45670 | TIGD3 | 220359 | 229789_at | 0.2633 | 0.0169 | |
| GSE53622 | TIGD3 | 220359 | 18984 | 0.2077 | 0.1780 | |
| GSE53624 | TIGD3 | 220359 | 18984 | 0.4868 | 0.0000 | |
| GSE63941 | TIGD3 | 220359 | 229789_at | 0.4341 | 0.1059 | |
| GSE77861 | TIGD3 | 220359 | 229789_at | -0.0536 | 0.7303 | |
| SRP159526 | TIGD3 | 220359 | RNAseq | 1.3667 | 0.0134 | |
| TCGA | TIGD3 | 220359 | RNAseq | 0.7736 | 0.0053 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TIGD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIGD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIGD3 | 220359 | 8 | 5 | 17 | |
| GSE20123 | TIGD3 | 220359 | 8 | 5 | 17 | |
| GSE43470 | TIGD3 | 220359 | 4 | 1 | 38 | |
| GSE46452 | TIGD3 | 220359 | 11 | 3 | 45 | |
| GSE47630 | TIGD3 | 220359 | 7 | 5 | 28 | |
| GSE54993 | TIGD3 | 220359 | 3 | 0 | 67 | |
| GSE54994 | TIGD3 | 220359 | 7 | 5 | 41 | |
| GSE60625 | TIGD3 | 220359 | 0 | 3 | 8 | |
| GSE74703 | TIGD3 | 220359 | 3 | 0 | 33 | |
| GSE74704 | TIGD3 | 220359 | 6 | 3 | 11 | |
| TCGA | TIGD3 | 220359 | 23 | 7 | 66 |
Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.
Somatic mutations of TIGD3:
Generating mutation plots.
Highly correlated genes for TIGD3:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIGD3 | DEFB119 | 0.688449 | 3 | 0 | 3 |
| TIGD3 | ASL | 0.688058 | 3 | 0 | 3 |
| TIGD3 | BDH1 | 0.669495 | 3 | 0 | 3 |
| TIGD3 | RABEP2 | 0.654688 | 3 | 0 | 3 |
| TIGD3 | NTSR1 | 0.640254 | 3 | 0 | 3 |
| TIGD3 | PPP4C | 0.632667 | 3 | 0 | 3 |
| TIGD3 | NPRL3 | 0.624983 | 3 | 0 | 3 |
| TIGD3 | ZFPL1 | 0.624588 | 4 | 0 | 3 |
| TIGD3 | LINC01089 | 0.608477 | 3 | 0 | 3 |
| TIGD3 | RAB26 | 0.604943 | 3 | 0 | 3 |
| TIGD3 | CLN3 | 0.585539 | 4 | 0 | 3 |
| TIGD3 | SRRM2-AS1 | 0.585327 | 3 | 0 | 3 |
| TIGD3 | GSX1 | 0.579343 | 3 | 0 | 3 |
| TIGD3 | NKX2-5 | 0.579122 | 3 | 0 | 3 |
| TIGD3 | CCDC137 | 0.575912 | 3 | 0 | 3 |
| TIGD3 | ACTL6B | 0.575173 | 4 | 0 | 3 |
| TIGD3 | EIF6 | 0.572123 | 3 | 0 | 3 |
| TIGD3 | ZSWIM3 | 0.571226 | 3 | 0 | 3 |
| TIGD3 | ACSS2 | 0.567259 | 4 | 0 | 3 |
| TIGD3 | CHRNA5 | 0.566137 | 3 | 0 | 3 |
For details and further investigation, click here
