| Full name: syndecan binding protein 2 | Alias Symbol: ST-2|SITAC18 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 27111 | HGNC ID: HGNC:15756 | Ensembl Gene: ENSG00000125775 | OMIM ID: 617358 |
| Drug and gene relationship at DGIdb | |||
Expression of SDCBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SDCBP2 | 27111 | 108304 | -1.9791 | 0.0000 | |
| GSE53624 | SDCBP2 | 27111 | 108304 | -1.9638 | 0.0000 | |
| GSE97050 | SDCBP2 | 27111 | A_23_P131899 | -0.0751 | 0.8906 | |
| SRP007169 | SDCBP2 | 27111 | RNAseq | -3.5381 | 0.0000 | |
| SRP008496 | SDCBP2 | 27111 | RNAseq | -3.7592 | 0.0000 | |
| SRP064894 | SDCBP2 | 27111 | RNAseq | -2.4792 | 0.0000 | |
| SRP133303 | SDCBP2 | 27111 | RNAseq | -1.8929 | 0.0000 | |
| SRP159526 | SDCBP2 | 27111 | RNAseq | -1.9466 | 0.0275 | |
| SRP193095 | SDCBP2 | 27111 | RNAseq | -2.3574 | 0.0000 | |
| SRP219564 | SDCBP2 | 27111 | RNAseq | -1.8925 | 0.0633 | |
| TCGA | SDCBP2 | 27111 | RNAseq | -0.2931 | 0.1387 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SDCBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDCBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDCBP2 | 27111 | 12 | 4 | 14 | |
| GSE20123 | SDCBP2 | 27111 | 13 | 4 | 13 | |
| GSE43470 | SDCBP2 | 27111 | 11 | 1 | 31 | |
| GSE46452 | SDCBP2 | 27111 | 26 | 1 | 32 | |
| GSE47630 | SDCBP2 | 27111 | 19 | 4 | 17 | |
| GSE54993 | SDCBP2 | 27111 | 2 | 14 | 54 | |
| GSE54994 | SDCBP2 | 27111 | 24 | 2 | 27 | |
| GSE60625 | SDCBP2 | 27111 | 0 | 0 | 11 | |
| GSE74703 | SDCBP2 | 27111 | 10 | 1 | 25 | |
| GSE74704 | SDCBP2 | 27111 | 8 | 2 | 10 | |
| TCGA | SDCBP2 | 27111 | 40 | 11 | 45 |
Total number of gains: 165; Total number of losses: 44; Total Number of normals: 279.
Somatic mutations of SDCBP2:
Generating mutation plots.
Highly correlated genes for SDCBP2:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDCBP2 | CEACAM3 | 0.81667 | 3 | 0 | 3 |
| SDCBP2 | DEGS2 | 0.807662 | 3 | 0 | 3 |
| SDCBP2 | EPS8L2 | 0.796936 | 3 | 0 | 3 |
| SDCBP2 | LIPH | 0.795817 | 3 | 0 | 3 |
| SDCBP2 | RAET1E | 0.789277 | 3 | 0 | 3 |
| SDCBP2 | CYP3A5 | 0.78792 | 3 | 0 | 3 |
| SDCBP2 | ZBTB7B | 0.775072 | 3 | 0 | 3 |
| SDCBP2 | KRT83 | 0.774467 | 3 | 0 | 3 |
| SDCBP2 | C3orf20 | 0.773776 | 3 | 0 | 3 |
| SDCBP2 | GCNT3 | 0.773073 | 3 | 0 | 3 |
| SDCBP2 | MAPK13 | 0.769785 | 3 | 0 | 3 |
| SDCBP2 | GRHL3 | 0.768685 | 4 | 0 | 4 |
| SDCBP2 | KCNK7 | 0.766405 | 3 | 0 | 3 |
| SDCBP2 | MYO5B | 0.760896 | 3 | 0 | 3 |
| SDCBP2 | LMO7 | 0.758945 | 3 | 0 | 3 |
| SDCBP2 | TMEM154 | 0.758433 | 4 | 0 | 4 |
| SDCBP2 | TTC22 | 0.756989 | 3 | 0 | 3 |
| SDCBP2 | POF1B | 0.753838 | 3 | 0 | 3 |
| SDCBP2 | NCCRP1 | 0.753789 | 4 | 0 | 4 |
| SDCBP2 | LGALS3 | 0.753471 | 3 | 0 | 3 |
For details and further investigation, click here
