| Full name: phosphatidylinositol transfer protein membrane associated 2 | Alias Symbol: RDGBA2|RDGB2|NIR3 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 57605 | HGNC ID: HGNC:21044 | Ensembl Gene: ENSG00000090975 | OMIM ID: 608920 |
| Drug and gene relationship at DGIdb | |||
Expression of PITPNM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PITPNM2 | 57605 | 1552924_a_at | -0.2397 | 0.3468 | |
| GSE26886 | PITPNM2 | 57605 | 232950_s_at | 0.0259 | 0.8822 | |
| GSE45670 | PITPNM2 | 57605 | 232950_s_at | -0.0572 | 0.5493 | |
| GSE53622 | PITPNM2 | 57605 | 145894 | -0.2651 | 0.0090 | |
| GSE53624 | PITPNM2 | 57605 | 145894 | 0.1003 | 0.1830 | |
| GSE63941 | PITPNM2 | 57605 | 232950_s_at | -0.1793 | 0.3781 | |
| GSE77861 | PITPNM2 | 57605 | 232950_s_at | -0.0040 | 0.9723 | |
| GSE97050 | PITPNM2 | 57605 | A_23_P401361 | -0.4209 | 0.2345 | |
| SRP007169 | PITPNM2 | 57605 | RNAseq | -0.0298 | 0.9508 | |
| SRP064894 | PITPNM2 | 57605 | RNAseq | -0.1217 | 0.5731 | |
| SRP133303 | PITPNM2 | 57605 | RNAseq | -0.3645 | 0.0666 | |
| SRP159526 | PITPNM2 | 57605 | RNAseq | -0.2634 | 0.3657 | |
| SRP193095 | PITPNM2 | 57605 | RNAseq | 0.3761 | 0.0178 | |
| SRP219564 | PITPNM2 | 57605 | RNAseq | -0.2454 | 0.5480 | |
| TCGA | PITPNM2 | 57605 | RNAseq | -0.2805 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PITPNM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PITPNM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PITPNM2 | 57605 | 5 | 5 | 20 | |
| GSE20123 | PITPNM2 | 57605 | 5 | 5 | 20 | |
| GSE43470 | PITPNM2 | 57605 | 2 | 1 | 40 | |
| GSE46452 | PITPNM2 | 57605 | 9 | 1 | 49 | |
| GSE47630 | PITPNM2 | 57605 | 9 | 3 | 28 | |
| GSE54993 | PITPNM2 | 57605 | 0 | 5 | 65 | |
| GSE54994 | PITPNM2 | 57605 | 4 | 8 | 41 | |
| GSE60625 | PITPNM2 | 57605 | 0 | 0 | 11 | |
| GSE74703 | PITPNM2 | 57605 | 2 | 0 | 34 | |
| GSE74704 | PITPNM2 | 57605 | 3 | 3 | 14 | |
| TCGA | PITPNM2 | 57605 | 21 | 11 | 64 |
Total number of gains: 60; Total number of losses: 42; Total Number of normals: 386.
Somatic mutations of PITPNM2:
Generating mutation plots.
Highly correlated genes for PITPNM2:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PITPNM2 | GFRA1 | 0.803645 | 3 | 0 | 3 |
| PITPNM2 | PDK2 | 0.792992 | 3 | 0 | 3 |
| PITPNM2 | RASSF3 | 0.789759 | 3 | 0 | 3 |
| PITPNM2 | BEGAIN | 0.778052 | 3 | 0 | 3 |
| PITPNM2 | DPH3 | 0.755147 | 3 | 0 | 3 |
| PITPNM2 | FAM131B | 0.748679 | 4 | 0 | 4 |
| PITPNM2 | ADH1B | 0.74143 | 3 | 0 | 3 |
| PITPNM2 | HOXA3 | 0.739201 | 3 | 0 | 3 |
| PITPNM2 | SSPN | 0.734663 | 3 | 0 | 3 |
| PITPNM2 | FBXO30 | 0.731652 | 3 | 0 | 3 |
| PITPNM2 | SCMH1 | 0.721176 | 3 | 0 | 3 |
| PITPNM2 | F10 | 0.718764 | 3 | 0 | 3 |
| PITPNM2 | PPP1R1B | 0.712423 | 3 | 0 | 3 |
| PITPNM2 | FRMD3 | 0.706543 | 3 | 0 | 3 |
| PITPNM2 | GNG2 | 0.700209 | 4 | 0 | 4 |
| PITPNM2 | COL14A1 | 0.700023 | 3 | 0 | 3 |
| PITPNM2 | P4HTM | 0.698131 | 3 | 0 | 3 |
| PITPNM2 | KCNN3 | 0.695748 | 3 | 0 | 3 |
| PITPNM2 | TSR2 | 0.695449 | 3 | 0 | 3 |
| PITPNM2 | RERGL | 0.693998 | 3 | 0 | 3 |
For details and further investigation, click here
