| Full name: poly(ADP-ribose) polymerase family member 16 | Alias Symbol: FLJ20509|FLJ25281|pART15 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 54956 | HGNC ID: HGNC:26040 | Ensembl Gene: ENSG00000138617 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PARP16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP16 | 54956 | 219034_at | -0.4569 | 0.3793 | |
| GSE20347 | PARP16 | 54956 | 219034_at | 0.0456 | 0.6785 | |
| GSE23400 | PARP16 | 54956 | 219034_at | -0.0424 | 0.3179 | |
| GSE26886 | PARP16 | 54956 | 219034_at | -0.0265 | 0.9160 | |
| GSE29001 | PARP16 | 54956 | 219034_at | -0.0727 | 0.7652 | |
| GSE38129 | PARP16 | 54956 | 219034_at | -0.0804 | 0.4586 | |
| GSE45670 | PARP16 | 54956 | 219034_at | -0.4596 | 0.0008 | |
| GSE53622 | PARP16 | 54956 | 2024 | -0.2626 | 0.0385 | |
| GSE53624 | PARP16 | 54956 | 2024 | -0.3976 | 0.0004 | |
| GSE63941 | PARP16 | 54956 | 219034_at | 0.2491 | 0.5002 | |
| GSE77861 | PARP16 | 54956 | 219034_at | -0.1804 | 0.2341 | |
| GSE97050 | PARP16 | 54956 | A_23_P163278 | -0.5178 | 0.1057 | |
| SRP007169 | PARP16 | 54956 | RNAseq | 0.1075 | 0.8030 | |
| SRP064894 | PARP16 | 54956 | RNAseq | -0.1970 | 0.1600 | |
| SRP133303 | PARP16 | 54956 | RNAseq | -0.1927 | 0.2506 | |
| SRP159526 | PARP16 | 54956 | RNAseq | -0.4286 | 0.0444 | |
| SRP193095 | PARP16 | 54956 | RNAseq | -0.1880 | 0.1038 | |
| SRP219564 | PARP16 | 54956 | RNAseq | -0.0373 | 0.9383 | |
| TCGA | PARP16 | 54956 | RNAseq | -0.0985 | 0.1096 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PARP16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP16 | 54956 | 7 | 3 | 20 | |
| GSE20123 | PARP16 | 54956 | 7 | 3 | 20 | |
| GSE43470 | PARP16 | 54956 | 4 | 6 | 33 | |
| GSE46452 | PARP16 | 54956 | 3 | 7 | 49 | |
| GSE47630 | PARP16 | 54956 | 8 | 10 | 22 | |
| GSE54993 | PARP16 | 54956 | 5 | 6 | 59 | |
| GSE54994 | PARP16 | 54956 | 6 | 7 | 40 | |
| GSE60625 | PARP16 | 54956 | 4 | 0 | 7 | |
| GSE74703 | PARP16 | 54956 | 4 | 3 | 29 | |
| GSE74704 | PARP16 | 54956 | 3 | 3 | 14 | |
| TCGA | PARP16 | 54956 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of PARP16:
Generating mutation plots.
Highly correlated genes for PARP16:
Showing top 20/668 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP16 | ZBED5 | 0.808944 | 3 | 0 | 3 |
| PARP16 | ABHD14B | 0.80312 | 3 | 0 | 3 |
| PARP16 | TTC19 | 0.78679 | 3 | 0 | 3 |
| PARP16 | BEGAIN | 0.767605 | 3 | 0 | 3 |
| PARP16 | RRAGB | 0.755639 | 3 | 0 | 3 |
| PARP16 | CUEDC1 | 0.734649 | 3 | 0 | 3 |
| PARP16 | FKTN | 0.729454 | 3 | 0 | 3 |
| PARP16 | PPM1L | 0.72929 | 5 | 0 | 4 |
| PARP16 | MTMR10 | 0.728869 | 4 | 0 | 3 |
| PARP16 | ARHGAP31 | 0.727371 | 4 | 0 | 4 |
| PARP16 | ZRANB1 | 0.725493 | 3 | 0 | 3 |
| PARP16 | MEIS1 | 0.720172 | 4 | 0 | 4 |
| PARP16 | GNAQ | 0.714912 | 4 | 0 | 4 |
| PARP16 | TMEM120A | 0.707606 | 3 | 0 | 3 |
| PARP16 | RCOR3 | 0.704135 | 3 | 0 | 3 |
| PARP16 | IFT46 | 0.701205 | 3 | 0 | 3 |
| PARP16 | LIMCH1 | 0.700925 | 4 | 0 | 4 |
| PARP16 | SH3D19 | 0.700666 | 3 | 0 | 3 |
| PARP16 | CHADL | 0.700052 | 3 | 0 | 3 |
| PARP16 | RGMA | 0.697819 | 4 | 0 | 4 |
For details and further investigation, click here
