| Full name: fibroblast growth factor 14 | Alias Symbol: FHF4|SCA27 | ||
| Type: protein-coding gene | Cytoband: 13q33.1 | ||
| Entrez ID: 2259 | HGNC ID: HGNC:3671 | Ensembl Gene: ENSG00000102466 | OMIM ID: 601515 |
| Drug and gene relationship at DGIdb | |||
FGF14 involved pathways:
Expression of FGF14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGF14 | 2259 | 230288_at | -0.8767 | 0.0579 | |
| GSE20347 | FGF14 | 2259 | 221310_at | -0.1431 | 0.0238 | |
| GSE23400 | FGF14 | 2259 | 221310_at | -0.2166 | 0.0000 | |
| GSE26886 | FGF14 | 2259 | 230288_at | -0.4720 | 0.1181 | |
| GSE29001 | FGF14 | 2259 | 221310_at | -0.1104 | 0.4336 | |
| GSE38129 | FGF14 | 2259 | 221310_at | -0.2130 | 0.0002 | |
| GSE45670 | FGF14 | 2259 | 230288_at | -1.2621 | 0.0000 | |
| GSE53622 | FGF14 | 2259 | 47563 | -1.6406 | 0.0000 | |
| GSE53624 | FGF14 | 2259 | 47563 | -2.1831 | 0.0000 | |
| GSE63941 | FGF14 | 2259 | 233185_at | -0.0436 | 0.8362 | |
| GSE77861 | FGF14 | 2259 | 233185_at | -0.0817 | 0.4299 | |
| GSE97050 | FGF14 | 2259 | A_23_P88033 | -0.6514 | 0.0888 | |
| SRP007169 | FGF14 | 2259 | RNAseq | -3.8903 | 0.0000 | |
| SRP064894 | FGF14 | 2259 | RNAseq | -1.3641 | 0.0039 | |
| SRP133303 | FGF14 | 2259 | RNAseq | -1.6571 | 0.0000 | |
| SRP159526 | FGF14 | 2259 | RNAseq | -1.8007 | 0.0010 | |
| SRP219564 | FGF14 | 2259 | RNAseq | -0.6750 | 0.3946 | |
| TCGA | FGF14 | 2259 | RNAseq | -0.8982 | 0.0029 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by FGF14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGF14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGF14 | 2259 | 4 | 9 | 17 | |
| GSE20123 | FGF14 | 2259 | 4 | 8 | 18 | |
| GSE43470 | FGF14 | 2259 | 4 | 12 | 27 | |
| GSE46452 | FGF14 | 2259 | 0 | 32 | 27 | |
| GSE47630 | FGF14 | 2259 | 3 | 26 | 11 | |
| GSE54993 | FGF14 | 2259 | 11 | 4 | 55 | |
| GSE54994 | FGF14 | 2259 | 6 | 10 | 37 | |
| GSE60625 | FGF14 | 2259 | 0 | 3 | 8 | |
| GSE74703 | FGF14 | 2259 | 3 | 10 | 23 | |
| GSE74704 | FGF14 | 2259 | 2 | 8 | 10 | |
| TCGA | FGF14 | 2259 | 15 | 34 | 47 |
Total number of gains: 52; Total number of losses: 156; Total Number of normals: 280.
Somatic mutations of FGF14:
Generating mutation plots.
Highly correlated genes for FGF14:
Showing top 20/758 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGF14 | SCARA5 | 0.804515 | 3 | 0 | 3 |
| FGF14 | ADAMTS9-AS2 | 0.783942 | 4 | 0 | 4 |
| FGF14 | LGALS13 | 0.751957 | 3 | 0 | 3 |
| FGF14 | MAMDC2 | 0.749981 | 4 | 0 | 4 |
| FGF14 | SYPL2 | 0.745312 | 3 | 0 | 3 |
| FGF14 | IFNA4 | 0.740758 | 3 | 0 | 3 |
| FGF14 | CDH19 | 0.737808 | 4 | 0 | 4 |
| FGF14 | NEGR1 | 0.737361 | 5 | 0 | 5 |
| FGF14 | SSBP2 | 0.733964 | 4 | 0 | 4 |
| FGF14 | MOB2 | 0.732567 | 4 | 0 | 4 |
| FGF14 | DCLK1 | 0.732198 | 5 | 0 | 4 |
| FGF14 | AQP6 | 0.731787 | 3 | 0 | 3 |
| FGF14 | PLCXD3 | 0.72325 | 5 | 0 | 5 |
| FGF14 | CELA3B | 0.720165 | 3 | 0 | 3 |
| FGF14 | SLC5A4 | 0.718269 | 3 | 0 | 3 |
| FGF14 | PSG7 | 0.718092 | 4 | 0 | 4 |
| FGF14 | ABCA6 | 0.714966 | 6 | 0 | 5 |
| FGF14 | ATOH8 | 0.711642 | 4 | 0 | 3 |
| FGF14 | SCN7A | 0.711002 | 6 | 0 | 6 |
| FGF14 | MRVI1 | 0.70952 | 4 | 0 | 4 |
For details and further investigation, click here
