| Full name: BRCA1/BRCA2-containing complex subunit 3 | Alias Symbol: C6.1A|BRCC36 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 79184 | HGNC ID: HGNC:24185 | Ensembl Gene: ENSG00000185515 | OMIM ID: 300617 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BRCC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BRCC3 | 79184 | 229436_x_at | -0.4967 | 0.1328 | |
| GSE20347 | BRCC3 | 79184 | 221196_x_at | -0.4988 | 0.0282 | |
| GSE23400 | BRCC3 | 79184 | 221196_x_at | -0.2256 | 0.0001 | |
| GSE26886 | BRCC3 | 79184 | 229436_x_at | -0.5392 | 0.0102 | |
| GSE29001 | BRCC3 | 79184 | 221196_x_at | -0.4415 | 0.2289 | |
| GSE38129 | BRCC3 | 79184 | 221196_x_at | -0.3560 | 0.0475 | |
| GSE45670 | BRCC3 | 79184 | 229436_x_at | -0.2952 | 0.0869 | |
| GSE53622 | BRCC3 | 79184 | 40087 | -0.3210 | 0.0000 | |
| GSE53624 | BRCC3 | 79184 | 50830 | -0.7313 | 0.0000 | |
| GSE63941 | BRCC3 | 79184 | 229436_x_at | 0.7180 | 0.0822 | |
| GSE77861 | BRCC3 | 79184 | 229436_x_at | -0.5091 | 0.0071 | |
| GSE97050 | BRCC3 | 79184 | A_23_P217659 | -0.1679 | 0.4631 | |
| SRP007169 | BRCC3 | 79184 | RNAseq | -0.8705 | 0.0549 | |
| SRP008496 | BRCC3 | 79184 | RNAseq | -0.8571 | 0.0010 | |
| SRP064894 | BRCC3 | 79184 | RNAseq | -0.5247 | 0.0092 | |
| SRP133303 | BRCC3 | 79184 | RNAseq | 0.0280 | 0.8805 | |
| SRP159526 | BRCC3 | 79184 | RNAseq | -0.6638 | 0.0083 | |
| SRP193095 | BRCC3 | 79184 | RNAseq | -0.6266 | 0.0000 | |
| SRP219564 | BRCC3 | 79184 | RNAseq | -0.4528 | 0.2013 | |
| TCGA | BRCC3 | 79184 | RNAseq | -0.0396 | 0.4861 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BRCC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BRCC3:
No record found for this gene.
Somatic mutations of BRCC3:
Generating mutation plots.
Highly correlated genes for BRCC3:
Showing top 20/1028 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BRCC3 | LINC00551 | 0.709817 | 4 | 0 | 4 |
| BRCC3 | SFTA2 | 0.703738 | 4 | 0 | 3 |
| BRCC3 | ZNF554 | 0.68123 | 4 | 0 | 3 |
| BRCC3 | ARHGAP27 | 0.680727 | 8 | 0 | 7 |
| BRCC3 | FAM214A | 0.677552 | 6 | 0 | 6 |
| BRCC3 | STRADB | 0.672355 | 7 | 0 | 7 |
| BRCC3 | STXBP5 | 0.671352 | 7 | 0 | 7 |
| BRCC3 | TMEM154 | 0.669064 | 6 | 0 | 6 |
| BRCC3 | ULK3 | 0.668666 | 7 | 0 | 6 |
| BRCC3 | VSIG2 | 0.667464 | 6 | 0 | 5 |
| BRCC3 | MMEL1 | 0.662621 | 4 | 0 | 3 |
| BRCC3 | KLB | 0.661001 | 6 | 0 | 6 |
| BRCC3 | COMMD1 | 0.660862 | 5 | 0 | 5 |
| BRCC3 | C15orf48 | 0.660647 | 5 | 0 | 5 |
| BRCC3 | SMDT1 | 0.660512 | 4 | 0 | 3 |
| BRCC3 | ZNF823 | 0.660102 | 8 | 0 | 6 |
| BRCC3 | C5orf66-AS1 | 0.658981 | 6 | 0 | 6 |
| BRCC3 | ATMIN | 0.658943 | 8 | 0 | 7 |
| BRCC3 | IMPACT | 0.657955 | 4 | 0 | 4 |
| BRCC3 | FLG-AS1 | 0.65658 | 6 | 0 | 6 |
For details and further investigation, click here
