| Full name: interactor of little elongation complex ELL subunit 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p15.32 | ||
| Entrez ID: 23379 | HGNC ID: HGNC:29154 | Ensembl Gene: ENSG00000164151 | OMIM ID: 617958 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ICE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ICE1 | 23379 | 209654_at | 0.5448 | 0.0559 | |
| GSE20347 | ICE1 | 23379 | 209654_at | 0.7117 | 0.0000 | |
| GSE23400 | ICE1 | 23379 | 209654_at | 0.7895 | 0.0000 | |
| GSE26886 | ICE1 | 23379 | 209654_at | 1.6523 | 0.0000 | |
| GSE29001 | ICE1 | 23379 | 209654_at | 0.7303 | 0.0009 | |
| GSE38129 | ICE1 | 23379 | 209654_at | 0.6238 | 0.0000 | |
| GSE45670 | ICE1 | 23379 | 209654_at | 0.3001 | 0.1066 | |
| GSE53622 | ICE1 | 23379 | 37082 | 0.5909 | 0.0000 | |
| GSE53624 | ICE1 | 23379 | 37082 | 0.6862 | 0.0000 | |
| GSE63941 | ICE1 | 23379 | 209654_at | 0.3076 | 0.5065 | |
| GSE77861 | ICE1 | 23379 | 209654_at | 1.0152 | 0.0094 | |
| SRP007169 | ICE1 | 23379 | RNAseq | 1.3116 | 0.0002 | |
| SRP008496 | ICE1 | 23379 | RNAseq | 1.2609 | 0.0000 | |
| SRP064894 | ICE1 | 23379 | RNAseq | 0.0955 | 0.6942 | |
| SRP133303 | ICE1 | 23379 | RNAseq | 0.6363 | 0.0014 | |
| SRP159526 | ICE1 | 23379 | RNAseq | 0.2253 | 0.2918 | |
| SRP193095 | ICE1 | 23379 | RNAseq | 0.6358 | 0.0000 | |
| SRP219564 | ICE1 | 23379 | RNAseq | 0.1615 | 0.4654 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ICE1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ICE1:
No record found for this gene.
Somatic mutations of ICE1:
Generating mutation plots.
Highly correlated genes for ICE1:
Showing top 20/1577 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ICE1 | CTHRC1 | 0.760578 | 6 | 0 | 6 |
| ICE1 | BRIX1 | 0.758217 | 10 | 0 | 10 |
| ICE1 | BRD9 | 0.752576 | 8 | 0 | 8 |
| ICE1 | FMNL2 | 0.739454 | 6 | 0 | 6 |
| ICE1 | CMSS1 | 0.732006 | 6 | 0 | 6 |
| ICE1 | ZNF697 | 0.731748 | 5 | 0 | 5 |
| ICE1 | HTRA3 | 0.730039 | 3 | 0 | 3 |
| ICE1 | WDR81 | 0.728859 | 3 | 0 | 3 |
| ICE1 | MED10 | 0.727694 | 6 | 0 | 5 |
| ICE1 | PLBD2 | 0.727576 | 5 | 0 | 5 |
| ICE1 | CBX3 | 0.719811 | 10 | 0 | 10 |
| ICE1 | DPY19L4 | 0.719751 | 10 | 0 | 10 |
| ICE1 | U2SURP | 0.716432 | 8 | 0 | 8 |
| ICE1 | LAPTM4B | 0.71381 | 10 | 0 | 9 |
| ICE1 | HLTF | 0.713349 | 10 | 0 | 9 |
| ICE1 | SLC41A1 | 0.711519 | 6 | 0 | 6 |
| ICE1 | SLC39A10 | 0.711005 | 6 | 0 | 5 |
| ICE1 | SMIM8 | 0.710675 | 5 | 0 | 5 |
| ICE1 | TRIP13 | 0.710437 | 10 | 0 | 10 |
| ICE1 | DROSHA | 0.709073 | 11 | 0 | 10 |
For details and further investigation, click here
