| Full name: SET domain containing 5 | Alias Symbol: FLJ10707 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 55209 | HGNC ID: HGNC:25566 | Ensembl Gene: ENSG00000168137 | OMIM ID: 615743 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SETD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SETD5 | 55209 | 221806_s_at | 0.2932 | 0.4280 | |
| GSE20347 | SETD5 | 55209 | 221806_s_at | 0.1534 | 0.4655 | |
| GSE23400 | SETD5 | 55209 | 221806_s_at | 0.1235 | 0.0452 | |
| GSE26886 | SETD5 | 55209 | 1569105_at | -0.1500 | 0.5037 | |
| GSE29001 | SETD5 | 55209 | 221806_s_at | 0.0018 | 0.9957 | |
| GSE38129 | SETD5 | 55209 | 221806_s_at | -0.0033 | 0.9879 | |
| GSE45670 | SETD5 | 55209 | 221806_s_at | 0.0066 | 0.9642 | |
| GSE53622 | SETD5 | 55209 | 108758 | -0.0982 | 0.0577 | |
| GSE53624 | SETD5 | 55209 | 108758 | -0.0964 | 0.0798 | |
| GSE63941 | SETD5 | 55209 | 221806_s_at | 0.4873 | 0.2902 | |
| GSE77861 | SETD5 | 55209 | 1569105_at | -0.0337 | 0.8471 | |
| GSE97050 | SETD5 | 55209 | A_33_P3376434 | -0.0848 | 0.7876 | |
| SRP007169 | SETD5 | 55209 | RNAseq | 1.3100 | 0.0100 | |
| SRP008496 | SETD5 | 55209 | RNAseq | 1.0936 | 0.0018 | |
| SRP064894 | SETD5 | 55209 | RNAseq | -0.1391 | 0.5111 | |
| SRP133303 | SETD5 | 55209 | RNAseq | -0.0656 | 0.4881 | |
| SRP159526 | SETD5 | 55209 | RNAseq | -0.1687 | 0.5279 | |
| SRP193095 | SETD5 | 55209 | RNAseq | 0.0739 | 0.5201 | |
| SRP219564 | SETD5 | 55209 | RNAseq | -0.3887 | 0.1414 | |
| TCGA | SETD5 | 55209 | RNAseq | -0.0413 | 0.3531 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SETD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SETD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SETD5 | 55209 | 1 | 18 | 11 | |
| GSE20123 | SETD5 | 55209 | 1 | 18 | 11 | |
| GSE43470 | SETD5 | 55209 | 0 | 21 | 22 | |
| GSE46452 | SETD5 | 55209 | 2 | 17 | 40 | |
| GSE47630 | SETD5 | 55209 | 3 | 22 | 15 | |
| GSE54993 | SETD5 | 55209 | 6 | 1 | 63 | |
| GSE54994 | SETD5 | 55209 | 3 | 31 | 19 | |
| GSE60625 | SETD5 | 55209 | 5 | 0 | 6 | |
| GSE74703 | SETD5 | 55209 | 0 | 17 | 19 | |
| GSE74704 | SETD5 | 55209 | 1 | 11 | 8 | |
| TCGA | SETD5 | 55209 | 5 | 65 | 26 |
Total number of gains: 27; Total number of losses: 221; Total Number of normals: 240.
Somatic mutations of SETD5:
Generating mutation plots.
Highly correlated genes for SETD5:
Showing top 20/197 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SETD5 | MAN1B1 | 0.75385 | 3 | 0 | 3 |
| SETD5 | NONO | 0.753411 | 3 | 0 | 3 |
| SETD5 | ZNF787 | 0.74487 | 3 | 0 | 3 |
| SETD5 | BRD9 | 0.744204 | 3 | 0 | 3 |
| SETD5 | CD33 | 0.726627 | 3 | 0 | 3 |
| SETD5 | TAF1L | 0.721018 | 3 | 0 | 3 |
| SETD5 | NUDT4 | 0.717871 | 3 | 0 | 3 |
| SETD5 | SNAPC4 | 0.707837 | 4 | 0 | 4 |
| SETD5 | TRIM47 | 0.701257 | 3 | 0 | 3 |
| SETD5 | TPSG1 | 0.699912 | 3 | 0 | 3 |
| SETD5 | CCDC167 | 0.691559 | 3 | 0 | 3 |
| SETD5 | HMBOX1 | 0.688838 | 4 | 0 | 3 |
| SETD5 | BCL9 | 0.688733 | 4 | 0 | 4 |
| SETD5 | PLEKHA4 | 0.688242 | 3 | 0 | 3 |
| SETD5 | MED9 | 0.687313 | 3 | 0 | 3 |
| SETD5 | GRIN3A | 0.682974 | 3 | 0 | 3 |
| SETD5 | CAMKK2 | 0.680477 | 3 | 0 | 3 |
| SETD5 | C20orf96 | 0.673972 | 4 | 0 | 4 |
| SETD5 | LHX3 | 0.663987 | 3 | 0 | 3 |
| SETD5 | POU3F4 | 0.662341 | 3 | 0 | 3 |
For details and further investigation, click here
