| Full name: leucine rich repeat containing 69 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q21.3 | ||
| Entrez ID: 100130742 | HGNC ID: HGNC:34303 | Ensembl Gene: ENSG00000214954 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC69:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC69 | 100130742 | 238214_at | 1.3711 | 0.1059 | |
| GSE26886 | LRRC69 | 100130742 | 238214_at | 0.6868 | 0.0052 | |
| GSE45670 | LRRC69 | 100130742 | 238214_at | 0.6055 | 0.0065 | |
| GSE53622 | LRRC69 | 100130742 | 139171 | 0.8735 | 0.0000 | |
| GSE53624 | LRRC69 | 100130742 | 139171 | 1.2897 | 0.0000 | |
| GSE63941 | LRRC69 | 100130742 | 238214_at | -0.7349 | 0.0338 | |
| GSE77861 | LRRC69 | 100130742 | 238214_at | 0.3965 | 0.0819 | |
| SRP064894 | LRRC69 | 100130742 | RNAseq | 1.3573 | 0.0000 | |
| SRP133303 | LRRC69 | 100130742 | RNAseq | 0.1770 | 0.4101 | |
| SRP159526 | LRRC69 | 100130742 | RNAseq | 1.8344 | 0.0041 | |
| SRP193095 | LRRC69 | 100130742 | RNAseq | 0.2529 | 0.0620 | |
| SRP219564 | LRRC69 | 100130742 | RNAseq | 1.2307 | 0.0023 | |
| TCGA | LRRC69 | 100130742 | RNAseq | 2.0940 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by LRRC69 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC69:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC69 | 100130742 | 14 | 1 | 15 | |
| GSE20123 | LRRC69 | 100130742 | 15 | 1 | 14 | |
| GSE43470 | LRRC69 | 100130742 | 20 | 1 | 22 | |
| GSE46452 | LRRC69 | 100130742 | 22 | 0 | 37 | |
| GSE47630 | LRRC69 | 100130742 | 24 | 0 | 16 | |
| GSE54993 | LRRC69 | 100130742 | 0 | 20 | 50 | |
| GSE54994 | LRRC69 | 100130742 | 33 | 1 | 19 | |
| GSE60625 | LRRC69 | 100130742 | 0 | 4 | 7 | |
| GSE74703 | LRRC69 | 100130742 | 17 | 1 | 18 | |
| GSE74704 | LRRC69 | 100130742 | 10 | 0 | 10 | |
| TCGA | LRRC69 | 100130742 | 56 | 1 | 39 |
Total number of gains: 211; Total number of losses: 30; Total Number of normals: 247.
Somatic mutations of LRRC69:
Generating mutation plots.
Highly correlated genes for LRRC69:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC69 | BRD9 | 0.801713 | 3 | 0 | 3 |
| LRRC69 | CA9 | 0.753513 | 3 | 0 | 3 |
| LRRC69 | FASTKD3 | 0.719326 | 3 | 0 | 3 |
| LRRC69 | CSTF3 | 0.719238 | 3 | 0 | 3 |
| LRRC69 | ACVR1C | 0.717237 | 4 | 0 | 4 |
| LRRC69 | MTRR | 0.714841 | 3 | 0 | 3 |
| LRRC69 | POLR3A | 0.714456 | 3 | 0 | 3 |
| LRRC69 | RICTOR | 0.704568 | 3 | 0 | 3 |
| LRRC69 | ZNF133 | 0.703194 | 3 | 0 | 3 |
| LRRC69 | ASXL1 | 0.692534 | 3 | 0 | 3 |
| LRRC69 | TBP | 0.684445 | 3 | 0 | 3 |
| LRRC69 | ZNF518B | 0.677897 | 4 | 0 | 4 |
| LRRC69 | MTERF3 | 0.675445 | 4 | 0 | 4 |
| LRRC69 | ICE1 | 0.674886 | 4 | 0 | 3 |
| LRRC69 | LAMA3 | 0.671348 | 3 | 0 | 3 |
| LRRC69 | DROSHA | 0.66944 | 4 | 0 | 3 |
| LRRC69 | SYT1 | 0.668265 | 3 | 0 | 3 |
| LRRC69 | CCDC142 | 0.664373 | 3 | 0 | 3 |
| LRRC69 | MORC2 | 0.662934 | 4 | 0 | 4 |
| LRRC69 | RAB23 | 0.659518 | 3 | 0 | 3 |
For details and further investigation, click here
