| Full name: cyclin K | Alias Symbol: CPR4 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 8812 | HGNC ID: HGNC:1596 | Ensembl Gene: ENSG00000090061 | OMIM ID: 603544 |
| Drug and gene relationship at DGIdb | |||
Expression of CCNK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNK | 8812 | 225824_at | 0.5691 | 0.0493 | |
| GSE20347 | CCNK | 8812 | 219273_at | 0.0317 | 0.6935 | |
| GSE23400 | CCNK | 8812 | 219273_at | -0.1165 | 0.0040 | |
| GSE26886 | CCNK | 8812 | 225824_at | 0.3029 | 0.1978 | |
| GSE29001 | CCNK | 8812 | 219273_at | -0.0191 | 0.9260 | |
| GSE38129 | CCNK | 8812 | 219273_at | 0.0157 | 0.8453 | |
| GSE45670 | CCNK | 8812 | 225824_at | 0.4365 | 0.0025 | |
| GSE53622 | CCNK | 8812 | 2915 | 0.6115 | 0.0000 | |
| GSE53624 | CCNK | 8812 | 2915 | 0.4768 | 0.0000 | |
| GSE63941 | CCNK | 8812 | 225824_at | 0.1523 | 0.6417 | |
| GSE77861 | CCNK | 8812 | 225824_at | 0.2139 | 0.5527 | |
| GSE97050 | CCNK | 8812 | A_24_P348925 | 0.7381 | 0.1296 | |
| SRP007169 | CCNK | 8812 | RNAseq | 0.6424 | 0.1259 | |
| SRP008496 | CCNK | 8812 | RNAseq | 0.7325 | 0.0190 | |
| SRP064894 | CCNK | 8812 | RNAseq | 0.2662 | 0.0960 | |
| SRP133303 | CCNK | 8812 | RNAseq | 0.5820 | 0.0000 | |
| SRP159526 | CCNK | 8812 | RNAseq | 0.2257 | 0.5163 | |
| SRP193095 | CCNK | 8812 | RNAseq | 0.1509 | 0.1950 | |
| SRP219564 | CCNK | 8812 | RNAseq | 0.6246 | 0.1339 | |
| TCGA | CCNK | 8812 | RNAseq | 0.1418 | 0.0033 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCNK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNK | 8812 | 10 | 5 | 15 | |
| GSE20123 | CCNK | 8812 | 10 | 4 | 16 | |
| GSE43470 | CCNK | 8812 | 7 | 4 | 32 | |
| GSE46452 | CCNK | 8812 | 17 | 3 | 39 | |
| GSE47630 | CCNK | 8812 | 11 | 8 | 21 | |
| GSE54993 | CCNK | 8812 | 3 | 8 | 59 | |
| GSE54994 | CCNK | 8812 | 21 | 4 | 28 | |
| GSE60625 | CCNK | 8812 | 0 | 2 | 9 | |
| GSE74703 | CCNK | 8812 | 6 | 3 | 27 | |
| GSE74704 | CCNK | 8812 | 6 | 3 | 11 | |
| TCGA | CCNK | 8812 | 31 | 19 | 46 |
Total number of gains: 122; Total number of losses: 63; Total Number of normals: 303.
Somatic mutations of CCNK:
Generating mutation plots.
Highly correlated genes for CCNK:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNK | YWHAG | 0.790788 | 4 | 0 | 4 |
| CCNK | CDCA2 | 0.77867 | 3 | 0 | 3 |
| CCNK | BRD9 | 0.760667 | 3 | 0 | 3 |
| CCNK | KDM1B | 0.749257 | 3 | 0 | 3 |
| CCNK | SPI1 | 0.748427 | 3 | 0 | 3 |
| CCNK | DMAP1 | 0.742502 | 3 | 0 | 3 |
| CCNK | PSEN1 | 0.740974 | 4 | 0 | 4 |
| CCNK | POLR3D | 0.740718 | 3 | 0 | 3 |
| CCNK | SARDH | 0.735863 | 3 | 0 | 3 |
| CCNK | IFNGR2 | 0.734657 | 3 | 0 | 3 |
| CCNK | IFNAR2 | 0.733231 | 3 | 0 | 3 |
| CCNK | COCH | 0.729583 | 3 | 0 | 3 |
| CCNK | SSH1 | 0.726003 | 3 | 0 | 3 |
| CCNK | EMG1 | 0.721222 | 3 | 0 | 3 |
| CCNK | TEAD4 | 0.719979 | 4 | 0 | 4 |
| CCNK | STIP1 | 0.712262 | 4 | 0 | 4 |
| CCNK | TSEN15 | 0.710267 | 3 | 0 | 3 |
| CCNK | RTKN | 0.70878 | 4 | 0 | 4 |
| CCNK | ZC3H18 | 0.706119 | 3 | 0 | 3 |
| CCNK | NAV1 | 0.701445 | 3 | 0 | 3 |
For details and further investigation, click here
