| Full name: basigin (Ok blood group) | Alias Symbol: EMMPRIN|CD147|EMPRIN | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 682 | HGNC ID: HGNC:1116 | Ensembl Gene: ENSG00000172270 | OMIM ID: 109480 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of BSG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BSG | 682 | 208677_s_at | 0.7744 | 0.0626 | |
| GSE20347 | BSG | 682 | 208677_s_at | 0.4627 | 0.0153 | |
| GSE23400 | BSG | 682 | 208677_s_at | 0.6156 | 0.0000 | |
| GSE26886 | BSG | 682 | 208677_s_at | 1.0688 | 0.0004 | |
| GSE29001 | BSG | 682 | 208677_s_at | 0.5214 | 0.0238 | |
| GSE38129 | BSG | 682 | 208677_s_at | 0.5658 | 0.0002 | |
| GSE45670 | BSG | 682 | 208677_s_at | 1.0568 | 0.0001 | |
| GSE53622 | BSG | 682 | 12017 | 0.6740 | 0.0000 | |
| GSE53624 | BSG | 682 | 12017 | 0.9656 | 0.0000 | |
| GSE63941 | BSG | 682 | 208677_s_at | 3.1875 | 0.0000 | |
| GSE77861 | BSG | 682 | 208677_s_at | 0.8577 | 0.0506 | |
| GSE97050 | BSG | 682 | A_24_P134266 | 0.5527 | 0.1189 | |
| SRP007169 | BSG | 682 | RNAseq | -0.1058 | 0.7360 | |
| SRP008496 | BSG | 682 | RNAseq | -0.2659 | 0.2220 | |
| SRP064894 | BSG | 682 | RNAseq | 0.8689 | 0.0010 | |
| SRP133303 | BSG | 682 | RNAseq | 0.9274 | 0.0003 | |
| SRP159526 | BSG | 682 | RNAseq | 0.7306 | 0.0011 | |
| SRP193095 | BSG | 682 | RNAseq | 0.4057 | 0.0230 | |
| SRP219564 | BSG | 682 | RNAseq | 0.6854 | 0.1349 | |
| TCGA | BSG | 682 | RNAseq | -0.0581 | 0.1932 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by BSG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BSG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BSG | 682 | 4 | 6 | 20 | |
| GSE20123 | BSG | 682 | 4 | 5 | 21 | |
| GSE43470 | BSG | 682 | 1 | 10 | 32 | |
| GSE46452 | BSG | 682 | 47 | 1 | 11 | |
| GSE47630 | BSG | 682 | 5 | 7 | 28 | |
| GSE54993 | BSG | 682 | 13 | 4 | 53 | |
| GSE54994 | BSG | 682 | 8 | 15 | 30 | |
| GSE60625 | BSG | 682 | 9 | 0 | 2 | |
| GSE74703 | BSG | 682 | 1 | 7 | 28 | |
| GSE74704 | BSG | 682 | 3 | 3 | 14 | |
| TCGA | BSG | 682 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of BSG:
Generating mutation plots.
Highly correlated genes for BSG:
Showing top 20/1811 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BSG | COPE | 0.845276 | 3 | 0 | 3 |
| BSG | SORL1 | 0.814476 | 3 | 0 | 3 |
| BSG | PDIA5 | 0.77664 | 3 | 0 | 3 |
| BSG | FMNL3 | 0.772724 | 4 | 0 | 4 |
| BSG | MRPL38 | 0.754506 | 4 | 0 | 4 |
| BSG | SLC35B2 | 0.750975 | 3 | 0 | 3 |
| BSG | ZSCAN21 | 0.733544 | 3 | 0 | 3 |
| BSG | FADS1 | 0.731693 | 3 | 0 | 3 |
| BSG | RAB34 | 0.73138 | 3 | 0 | 3 |
| BSG | INPP5B | 0.724374 | 3 | 0 | 3 |
| BSG | HES4 | 0.722379 | 4 | 0 | 3 |
| BSG | ZBED4 | 0.718776 | 3 | 0 | 3 |
| BSG | SIX4 | 0.717077 | 7 | 0 | 6 |
| BSG | RILPL1 | 0.71492 | 3 | 0 | 3 |
| BSG | RAD18 | 0.713759 | 3 | 0 | 3 |
| BSG | ABHD2 | 0.713163 | 3 | 0 | 3 |
| BSG | WDR89 | 0.711275 | 4 | 0 | 3 |
| BSG | STPG1 | 0.709555 | 4 | 0 | 4 |
| BSG | BANF1 | 0.708127 | 11 | 0 | 10 |
| BSG | KRTCAP2 | 0.704684 | 4 | 0 | 4 |
For details and further investigation, click here
