| Full name: abhydrolase domain containing 2 | Alias Symbol: LABH2 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 11057 | HGNC ID: HGNC:18717 | Ensembl Gene: ENSG00000140526 | OMIM ID: 612196 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ABHD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD2 | 11057 | 225337_at | 0.1966 | 0.7676 | |
| GSE20347 | ABHD2 | 11057 | 63825_at | 0.3149 | 0.2899 | |
| GSE23400 | ABHD2 | 11057 | 205566_at | 0.1811 | 0.0139 | |
| GSE26886 | ABHD2 | 11057 | 225337_at | 0.5777 | 0.0546 | |
| GSE29001 | ABHD2 | 11057 | 63825_at | 0.0006 | 0.9977 | |
| GSE38129 | ABHD2 | 11057 | 63825_at | 0.4317 | 0.0640 | |
| GSE45670 | ABHD2 | 11057 | 225337_at | -0.0437 | 0.8768 | |
| GSE53622 | ABHD2 | 11057 | 17360 | 0.0012 | 0.9917 | |
| GSE53624 | ABHD2 | 11057 | 121279 | -0.2050 | 0.0008 | |
| GSE63941 | ABHD2 | 11057 | 63825_at | -0.0399 | 0.9632 | |
| GSE77861 | ABHD2 | 11057 | 225337_at | 0.4877 | 0.1317 | |
| GSE97050 | ABHD2 | 11057 | A_23_P395172 | 0.2451 | 0.3655 | |
| SRP007169 | ABHD2 | 11057 | RNAseq | 0.0343 | 0.9328 | |
| SRP008496 | ABHD2 | 11057 | RNAseq | 0.3261 | 0.1505 | |
| SRP064894 | ABHD2 | 11057 | RNAseq | 0.0679 | 0.7709 | |
| SRP133303 | ABHD2 | 11057 | RNAseq | 0.1581 | 0.3692 | |
| SRP159526 | ABHD2 | 11057 | RNAseq | 0.9738 | 0.0544 | |
| SRP193095 | ABHD2 | 11057 | RNAseq | -0.1475 | 0.6420 | |
| SRP219564 | ABHD2 | 11057 | RNAseq | -0.0044 | 0.9924 | |
| TCGA | ABHD2 | 11057 | RNAseq | -0.3500 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABHD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD2 | 11057 | 8 | 3 | 19 | |
| GSE20123 | ABHD2 | 11057 | 8 | 3 | 19 | |
| GSE43470 | ABHD2 | 11057 | 5 | 4 | 34 | |
| GSE46452 | ABHD2 | 11057 | 3 | 7 | 49 | |
| GSE47630 | ABHD2 | 11057 | 8 | 11 | 21 | |
| GSE54993 | ABHD2 | 11057 | 4 | 6 | 60 | |
| GSE54994 | ABHD2 | 11057 | 7 | 6 | 40 | |
| GSE60625 | ABHD2 | 11057 | 4 | 0 | 7 | |
| GSE74703 | ABHD2 | 11057 | 4 | 3 | 29 | |
| GSE74704 | ABHD2 | 11057 | 4 | 2 | 14 | |
| TCGA | ABHD2 | 11057 | 17 | 11 | 68 |
Total number of gains: 72; Total number of losses: 56; Total Number of normals: 360.
Somatic mutations of ABHD2:
Generating mutation plots.
Highly correlated genes for ABHD2:
Showing top 20/386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD2 | TRIM35 | 0.805152 | 3 | 0 | 3 |
| ABHD2 | SMCR8 | 0.774603 | 3 | 0 | 3 |
| ABHD2 | WBP11 | 0.77427 | 3 | 0 | 3 |
| ABHD2 | DGKD | 0.757779 | 3 | 0 | 3 |
| ABHD2 | AMMECR1L | 0.756802 | 3 | 0 | 3 |
| ABHD2 | CD109 | 0.744136 | 3 | 0 | 3 |
| ABHD2 | CD200 | 0.742321 | 3 | 0 | 3 |
| ABHD2 | ZBED1 | 0.738371 | 3 | 0 | 3 |
| ABHD2 | IL13RA2 | 0.736964 | 3 | 0 | 3 |
| ABHD2 | AFTPH | 0.732915 | 3 | 0 | 3 |
| ABHD2 | LRP6 | 0.730743 | 4 | 0 | 4 |
| ABHD2 | OGDH | 0.728333 | 3 | 0 | 3 |
| ABHD2 | MRPS30 | 0.725618 | 3 | 0 | 3 |
| ABHD2 | SGTB | 0.724879 | 3 | 0 | 3 |
| ABHD2 | PSMG2 | 0.723986 | 3 | 0 | 3 |
| ABHD2 | OAF | 0.722991 | 3 | 0 | 3 |
| ABHD2 | GOPC | 0.722542 | 3 | 0 | 3 |
| ABHD2 | ORAI1 | 0.721922 | 3 | 0 | 3 |
| ABHD2 | MRI1 | 0.720779 | 3 | 0 | 3 |
| ABHD2 | FCGRT | 0.720319 | 3 | 0 | 3 |
For details and further investigation, click here
