PLSCR1

 

Full name: phospholipid scramblase 1 Alias Symbol: MMTRA1B
Type: protein-coding gene Cytoband: 3q24
Entrez ID: 5359 HGNC ID: HGNC:9092 Ensembl Gene: ENSG00000188313 OMIM ID: 604170
Drug and gene relationship at DGIdb

 

Expression of PLSCR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PLSCR1 5359 202446_s_at 0.2429 0.4079
GSE20347 PLSCR1 5359 202446_s_at 0.4247 0.1352
GSE23400 PLSCR1 5359 202446_s_at 0.4330 0.0004
GSE26886 PLSCR1 5359 202446_s_at -1.0036 0.0011
GSE29001 PLSCR1 5359 202446_s_at 0.7121 0.0287
GSE38129 PLSCR1 5359 202446_s_at 0.4001 0.0600
GSE45670 PLSCR1 5359 202446_s_at 0.8180 0.0006
GSE53622 PLSCR1 5359 28768 0.3439 0.0010
GSE53624 PLSCR1 5359 28768 0.4044 0.0001
GSE63941 PLSCR1 5359 202446_s_at 0.6172 0.6657
GSE77861 PLSCR1 5359 202446_s_at 0.1227 0.7450
GSE97050 PLSCR1 5359 A_23_P69109 0.2854 0.6268
SRP007169 PLSCR1 5359 RNAseq 0.0578 0.8950
SRP008496 PLSCR1 5359 RNAseq -0.1256 0.7059
SRP064894 PLSCR1 5359 RNAseq 0.6451 0.0179
SRP133303 PLSCR1 5359 RNAseq 0.4881 0.0373
SRP159526 PLSCR1 5359 RNAseq -0.3397 0.5160
SRP193095 PLSCR1 5359 RNAseq 0.4011 0.0271
SRP219564 PLSCR1 5359 RNAseq 0.4973 0.4421
TCGA PLSCR1 5359 RNAseq 0.2618 0.0002

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by PLSCR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PLSCR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PLSCR1 5359 22 0 8
GSE20123 PLSCR1 5359 22 0 8
GSE43470 PLSCR1 5359 23 0 20
GSE46452 PLSCR1 5359 16 3 40
GSE47630 PLSCR1 5359 19 3 18
GSE54993 PLSCR1 5359 1 9 60
GSE54994 PLSCR1 5359 34 1 18
GSE60625 PLSCR1 5359 0 6 5
GSE74703 PLSCR1 5359 20 0 16
GSE74704 PLSCR1 5359 15 0 5
TCGA PLSCR1 5359 67 2 27

Total number of gains: 239; Total number of losses: 24; Total Number of normals: 225.  

 

Somatic mutations of PLSCR1:

 

Generating mutation plots.

 

Highly correlated genes for PLSCR1:

 

Showing top 20/285 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLSCR1RNF2130.824157303
PLSCR1CCDC85C0.82303303
PLSCR1PARP90.741436808
PLSCR1ELP40.73758303
PLSCR1DGCR20.728193303
PLSCR1QSOX20.726912303
PLSCR1CDCA70.71841403
PLSCR1CD800.717484303
PLSCR1SMAD10.716752303
PLSCR1SYMPK0.708981303
PLSCR1RAB27A0.704608303
PLSCR1RBM8A0.703916303
PLSCR1BTG10.703622303
PLSCR1DDX60L0.698622403
PLSCR1PLEKHA70.694712303
PLSCR1SMAP20.691849303
PLSCR1RNF20.691061303
PLSCR1YTHDF30.689907303
PLSCR1TRIM470.689318303
PLSCR1AKAP17A0.686992303

For details and further investigation, click here