| Full name: basic leucine zipper and W2 domains 2 | Alias Symbol: HSPC028|MST017|MSTP017 | ||
| Type: protein-coding gene | Cytoband: 7p21.1 | ||
| Entrez ID: 28969 | HGNC ID: HGNC:18808 | Ensembl Gene: ENSG00000136261 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BZW2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BZW2 | 28969 | 217809_at | 0.4688 | 0.1323 | |
| GSE20347 | BZW2 | 28969 | 217809_at | 0.5502 | 0.0016 | |
| GSE23400 | BZW2 | 28969 | 217809_at | 0.4824 | 0.0000 | |
| GSE26886 | BZW2 | 28969 | 217809_at | 0.9733 | 0.0000 | |
| GSE29001 | BZW2 | 28969 | 217809_at | 0.2648 | 0.2876 | |
| GSE38129 | BZW2 | 28969 | 217809_at | 0.5904 | 0.0001 | |
| GSE45670 | BZW2 | 28969 | 217809_at | 0.3145 | 0.0723 | |
| GSE53622 | BZW2 | 28969 | 119355 | 0.3685 | 0.0000 | |
| GSE53624 | BZW2 | 28969 | 119355 | 0.5185 | 0.0000 | |
| GSE63941 | BZW2 | 28969 | 217809_at | 1.2051 | 0.0048 | |
| GSE77861 | BZW2 | 28969 | 217809_at | 0.2307 | 0.4555 | |
| GSE97050 | BZW2 | 28969 | A_33_P3216237 | 0.3145 | 0.3820 | |
| SRP007169 | BZW2 | 28969 | RNAseq | 0.4163 | 0.2883 | |
| SRP008496 | BZW2 | 28969 | RNAseq | 0.7208 | 0.0439 | |
| SRP064894 | BZW2 | 28969 | RNAseq | 0.1881 | 0.1257 | |
| SRP133303 | BZW2 | 28969 | RNAseq | 0.5056 | 0.0012 | |
| SRP159526 | BZW2 | 28969 | RNAseq | 0.5494 | 0.1212 | |
| SRP193095 | BZW2 | 28969 | RNAseq | -0.0404 | 0.7705 | |
| SRP219564 | BZW2 | 28969 | RNAseq | 0.0265 | 0.9399 | |
| TCGA | BZW2 | 28969 | RNAseq | 0.0585 | 0.2613 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BZW2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BZW2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BZW2 | 28969 | 14 | 2 | 14 | |
| GSE20123 | BZW2 | 28969 | 14 | 2 | 14 | |
| GSE43470 | BZW2 | 28969 | 5 | 0 | 38 | |
| GSE46452 | BZW2 | 28969 | 11 | 1 | 47 | |
| GSE47630 | BZW2 | 28969 | 9 | 1 | 30 | |
| GSE54993 | BZW2 | 28969 | 0 | 6 | 64 | |
| GSE54994 | BZW2 | 28969 | 21 | 1 | 31 | |
| GSE60625 | BZW2 | 28969 | 0 | 0 | 11 | |
| GSE74703 | BZW2 | 28969 | 5 | 0 | 31 | |
| GSE74704 | BZW2 | 28969 | 8 | 2 | 10 | |
| TCGA | BZW2 | 28969 | 56 | 5 | 35 |
Total number of gains: 143; Total number of losses: 20; Total Number of normals: 325.
Somatic mutations of BZW2:
Generating mutation plots.
Highly correlated genes for BZW2:
Showing top 20/1264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BZW2 | MICALCL | 0.808949 | 3 | 0 | 3 |
| BZW2 | PLCG1 | 0.769242 | 4 | 0 | 4 |
| BZW2 | ZSCAN29 | 0.755861 | 3 | 0 | 3 |
| BZW2 | LRRC58 | 0.749071 | 4 | 0 | 4 |
| BZW2 | UBTD2 | 0.740257 | 4 | 0 | 3 |
| BZW2 | HRH1 | 0.740161 | 3 | 0 | 3 |
| BZW2 | LSM5 | 0.734142 | 13 | 0 | 13 |
| BZW2 | MMP15 | 0.731373 | 4 | 0 | 3 |
| BZW2 | SPNS1 | 0.721205 | 3 | 0 | 3 |
| BZW2 | NOP10 | 0.719915 | 4 | 0 | 4 |
| BZW2 | MCMBP | 0.719163 | 5 | 0 | 4 |
| BZW2 | PRR12 | 0.710352 | 3 | 0 | 3 |
| BZW2 | CLASRP | 0.709961 | 3 | 0 | 3 |
| BZW2 | AIMP2 | 0.70706 | 11 | 0 | 10 |
| BZW2 | RAB11B | 0.704559 | 3 | 0 | 3 |
| BZW2 | ATXN1L | 0.703202 | 3 | 0 | 3 |
| BZW2 | PET117 | 0.699712 | 5 | 0 | 4 |
| BZW2 | CEP120 | 0.694391 | 3 | 0 | 3 |
| BZW2 | ALKBH6 | 0.691025 | 4 | 0 | 3 |
| BZW2 | PKP4 | 0.689764 | 3 | 0 | 3 |
For details and further investigation, click here
