| Full name: aminoacyl tRNA synthetase complex interacting multifunctional protein 2 | Alias Symbol: p38|PRO0992|JTV-1|JTV1 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 7965 | HGNC ID: HGNC:20609 | Ensembl Gene: ENSG00000106305 | OMIM ID: 600859 |
| Drug and gene relationship at DGIdb | |||
Expression of AIMP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AIMP2 | 7965 | 209971_x_at | 0.2266 | 0.5400 | |
| GSE20347 | AIMP2 | 7965 | 209971_x_at | 0.6331 | 0.0003 | |
| GSE23400 | AIMP2 | 7965 | 202138_x_at | 0.4900 | 0.0000 | |
| GSE26886 | AIMP2 | 7965 | 209971_x_at | 0.8191 | 0.0001 | |
| GSE29001 | AIMP2 | 7965 | 209971_x_at | 0.4625 | 0.0808 | |
| GSE38129 | AIMP2 | 7965 | 209971_x_at | 0.8021 | 0.0000 | |
| GSE45670 | AIMP2 | 7965 | 209971_x_at | 0.5918 | 0.0000 | |
| GSE63941 | AIMP2 | 7965 | 202138_x_at | 1.2789 | 0.0051 | |
| GSE77861 | AIMP2 | 7965 | 202138_x_at | 0.4490 | 0.0642 | |
| GSE97050 | AIMP2 | 7965 | A_23_P70991 | 0.3925 | 0.2780 | |
| SRP007169 | AIMP2 | 7965 | RNAseq | 0.5624 | 0.3703 | |
| SRP064894 | AIMP2 | 7965 | RNAseq | 0.7382 | 0.0003 | |
| SRP133303 | AIMP2 | 7965 | RNAseq | 0.6028 | 0.0001 | |
| SRP159526 | AIMP2 | 7965 | RNAseq | 0.6253 | 0.1575 | |
| SRP193095 | AIMP2 | 7965 | RNAseq | 0.2867 | 0.0582 | |
| SRP219564 | AIMP2 | 7965 | RNAseq | 0.5758 | 0.1765 | |
| TCGA | AIMP2 | 7965 | RNAseq | 0.4041 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AIMP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of AIMP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AIMP2 | 7965 | 14 | 1 | 15 | |
| GSE20123 | AIMP2 | 7965 | 14 | 1 | 15 | |
| GSE43470 | AIMP2 | 7965 | 6 | 1 | 36 | |
| GSE46452 | AIMP2 | 7965 | 13 | 1 | 45 | |
| GSE47630 | AIMP2 | 7965 | 9 | 1 | 30 | |
| GSE54993 | AIMP2 | 7965 | 0 | 6 | 64 | |
| GSE54994 | AIMP2 | 7965 | 20 | 1 | 32 | |
| GSE60625 | AIMP2 | 7965 | 0 | 0 | 11 | |
| GSE74703 | AIMP2 | 7965 | 6 | 0 | 30 | |
| GSE74704 | AIMP2 | 7965 | 9 | 0 | 11 | |
| TCGA | AIMP2 | 7965 | 55 | 5 | 36 |
Total number of gains: 146; Total number of losses: 17; Total Number of normals: 325.
Somatic mutations of AIMP2:
Generating mutation plots.
Highly correlated genes for AIMP2:
Showing top 20/1743 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AIMP2 | RP9 | 0.801528 | 4 | 0 | 4 |
| AIMP2 | RPA3 | 0.763904 | 11 | 0 | 11 |
| AIMP2 | ZNF766 | 0.76234 | 3 | 0 | 3 |
| AIMP2 | TTL | 0.761024 | 5 | 0 | 5 |
| AIMP2 | LARP6 | 0.754424 | 4 | 0 | 4 |
| AIMP2 | KRTCAP2 | 0.751797 | 4 | 0 | 4 |
| AIMP2 | LSM5 | 0.750379 | 11 | 0 | 10 |
| AIMP2 | ANKRD54 | 0.746892 | 3 | 0 | 3 |
| AIMP2 | DNAH14 | 0.745229 | 4 | 0 | 4 |
| AIMP2 | GMCL1 | 0.739225 | 3 | 0 | 3 |
| AIMP2 | MSTO1 | 0.736451 | 4 | 0 | 3 |
| AIMP2 | RILPL2 | 0.735886 | 3 | 0 | 3 |
| AIMP2 | MRPL47 | 0.734065 | 6 | 0 | 5 |
| AIMP2 | NUDT1 | 0.732157 | 11 | 0 | 10 |
| AIMP2 | ABCB6 | 0.731494 | 3 | 0 | 3 |
| AIMP2 | FAM220A | 0.730699 | 5 | 0 | 5 |
| AIMP2 | FANCM | 0.729944 | 3 | 0 | 3 |
| AIMP2 | HAUS1 | 0.726149 | 3 | 0 | 3 |
| AIMP2 | ASB7 | 0.725658 | 4 | 0 | 3 |
| AIMP2 | SPSB2 | 0.725153 | 4 | 0 | 3 |
For details and further investigation, click here
