| Full name: NOP10 ribonucleoprotein | Alias Symbol: NOP10P|MGC70651 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 55505 | HGNC ID: HGNC:14378 | Ensembl Gene: ENSG00000182117 | OMIM ID: 606471 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOP10 | 55505 | 217962_at | 0.1059 | 0.8763 | |
| GSE20347 | NOP10 | 55505 | 217962_at | 0.1039 | 0.6622 | |
| GSE23400 | NOP10 | 55505 | 217962_at | 0.0618 | 0.4251 | |
| GSE26886 | NOP10 | 55505 | 217962_at | 0.3858 | 0.0360 | |
| GSE29001 | NOP10 | 55505 | 217962_at | -0.0252 | 0.9237 | |
| GSE38129 | NOP10 | 55505 | 217962_at | 0.1539 | 0.3817 | |
| GSE45670 | NOP10 | 55505 | 217962_at | 0.1204 | 0.4334 | |
| GSE53622 | NOP10 | 55505 | 57113 | 0.0806 | 0.4526 | |
| GSE53624 | NOP10 | 55505 | 57113 | 0.0999 | 0.0807 | |
| GSE63941 | NOP10 | 55505 | 217962_at | 0.2128 | 0.5257 | |
| GSE77861 | NOP10 | 55505 | 217962_at | -0.1277 | 0.6631 | |
| GSE97050 | NOP10 | 55505 | A_23_P54477 | 0.2070 | 0.6428 | |
| SRP007169 | NOP10 | 55505 | RNAseq | -0.6226 | 0.0848 | |
| SRP008496 | NOP10 | 55505 | RNAseq | -0.8180 | 0.0003 | |
| SRP064894 | NOP10 | 55505 | RNAseq | 0.0951 | 0.7240 | |
| SRP133303 | NOP10 | 55505 | RNAseq | 0.1141 | 0.5466 | |
| SRP159526 | NOP10 | 55505 | RNAseq | -0.1468 | 0.6168 | |
| SRP193095 | NOP10 | 55505 | RNAseq | -0.3873 | 0.0132 | |
| SRP219564 | NOP10 | 55505 | RNAseq | -0.4109 | 0.1923 | |
| TCGA | NOP10 | 55505 | RNAseq | 0.1841 | 0.0099 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP10 | 55505 | 3 | 6 | 21 | |
| GSE20123 | NOP10 | 55505 | 3 | 6 | 21 | |
| GSE43470 | NOP10 | 55505 | 4 | 4 | 35 | |
| GSE46452 | NOP10 | 55505 | 3 | 7 | 49 | |
| GSE47630 | NOP10 | 55505 | 8 | 11 | 21 | |
| GSE54993 | NOP10 | 55505 | 4 | 6 | 60 | |
| GSE54994 | NOP10 | 55505 | 5 | 8 | 40 | |
| GSE60625 | NOP10 | 55505 | 4 | 0 | 7 | |
| GSE74703 | NOP10 | 55505 | 4 | 3 | 29 | |
| GSE74704 | NOP10 | 55505 | 2 | 5 | 13 | |
| TCGA | NOP10 | 55505 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 74; Total Number of normals: 361.
Somatic mutations of NOP10:
Generating mutation plots.
Highly correlated genes for NOP10:
Showing top 20/206 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP10 | LSM12 | 0.743329 | 3 | 0 | 3 |
| NOP10 | RNF40 | 0.741614 | 3 | 0 | 3 |
| NOP10 | RPS24 | 0.734423 | 3 | 0 | 3 |
| NOP10 | BZW2 | 0.719915 | 4 | 0 | 4 |
| NOP10 | TRAF7 | 0.713428 | 3 | 0 | 3 |
| NOP10 | NPRL3 | 0.712266 | 3 | 0 | 3 |
| NOP10 | TXNL1 | 0.710954 | 3 | 0 | 3 |
| NOP10 | PSPC1 | 0.703467 | 3 | 0 | 3 |
| NOP10 | TSPAN5 | 0.702497 | 3 | 0 | 3 |
| NOP10 | BMP1 | 0.69459 | 3 | 0 | 3 |
| NOP10 | CYCS | 0.693194 | 3 | 0 | 3 |
| NOP10 | DDX19A | 0.690612 | 3 | 0 | 3 |
| NOP10 | SPPL2A | 0.688475 | 3 | 0 | 3 |
| NOP10 | ZNF484 | 0.68792 | 3 | 0 | 3 |
| NOP10 | KCTD1 | 0.687226 | 3 | 0 | 3 |
| NOP10 | SARNP | 0.687202 | 3 | 0 | 3 |
| NOP10 | WDR47 | 0.661918 | 3 | 0 | 3 |
| NOP10 | FAN1 | 0.660277 | 3 | 0 | 3 |
| NOP10 | ANKS6 | 0.658694 | 4 | 0 | 3 |
| NOP10 | CARD10 | 0.65794 | 3 | 0 | 3 |
For details and further investigation, click here
