| Full name: keratin 13 | Alias Symbol: K13|CK13|MGC3781|MGC161462 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3860 | HGNC ID: HGNC:6415 | Ensembl Gene: ENSG00000171401 | OMIM ID: 148065 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT13 | 3860 | 207935_s_at | -1.8632 | 0.1425 | |
| GSE20347 | KRT13 | 3860 | 207935_s_at | -3.9837 | 0.0000 | |
| GSE23400 | KRT13 | 3860 | 207935_s_at | -2.9787 | 0.0000 | |
| GSE26886 | KRT13 | 3860 | 207935_s_at | -6.3996 | 0.0000 | |
| GSE29001 | KRT13 | 3860 | 207935_s_at | -5.2663 | 0.0001 | |
| GSE38129 | KRT13 | 3860 | 207935_s_at | -2.4658 | 0.0107 | |
| GSE45670 | KRT13 | 3860 | 207935_s_at | -1.0066 | 0.0362 | |
| GSE53622 | KRT13 | 3860 | 26109 | -2.6344 | 0.0000 | |
| GSE53624 | KRT13 | 3860 | 26109 | -2.6296 | 0.0000 | |
| GSE63941 | KRT13 | 3860 | 207935_s_at | 3.8379 | 0.0993 | |
| GSE77861 | KRT13 | 3860 | 207935_s_at | -3.2618 | 0.1040 | |
| GSE97050 | KRT13 | 3860 | A_24_P228149 | -2.0138 | 0.1204 | |
| SRP007169 | KRT13 | 3860 | RNAseq | -6.9868 | 0.0000 | |
| SRP008496 | KRT13 | 3860 | RNAseq | -6.3095 | 0.0000 | |
| SRP064894 | KRT13 | 3860 | RNAseq | -5.9699 | 0.0000 | |
| SRP133303 | KRT13 | 3860 | RNAseq | -6.1232 | 0.0000 | |
| SRP159526 | KRT13 | 3860 | RNAseq | -6.7673 | 0.0000 | |
| SRP219564 | KRT13 | 3860 | RNAseq | -4.7924 | 0.0003 | |
| TCGA | KRT13 | 3860 | RNAseq | 0.2226 | 0.6032 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by KRT13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT13 | 3860 | 6 | 2 | 22 | |
| GSE20123 | KRT13 | 3860 | 6 | 2 | 22 | |
| GSE43470 | KRT13 | 3860 | 1 | 2 | 40 | |
| GSE46452 | KRT13 | 3860 | 34 | 0 | 25 | |
| GSE47630 | KRT13 | 3860 | 8 | 1 | 31 | |
| GSE54993 | KRT13 | 3860 | 3 | 4 | 63 | |
| GSE54994 | KRT13 | 3860 | 8 | 5 | 40 | |
| GSE60625 | KRT13 | 3860 | 4 | 0 | 7 | |
| GSE74703 | KRT13 | 3860 | 1 | 1 | 34 | |
| GSE74704 | KRT13 | 3860 | 4 | 1 | 15 | |
| TCGA | KRT13 | 3860 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT13:
Generating mutation plots.
Highly correlated genes for KRT13:
Showing top 20/1155 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT13 | SPRR3 | 0.901338 | 12 | 0 | 12 |
| KRT13 | CRNN | 0.876593 | 12 | 0 | 12 |
| KRT13 | MAL | 0.874534 | 12 | 0 | 12 |
| KRT13 | CYSRT1 | 0.873653 | 6 | 0 | 6 |
| KRT13 | KRT4 | 0.87363 | 13 | 0 | 13 |
| KRT13 | TMPRSS11B | 0.865 | 8 | 0 | 8 |
| KRT13 | C5orf66-AS1 | 0.856901 | 6 | 0 | 6 |
| KRT13 | CLCA4 | 0.850222 | 13 | 0 | 13 |
| KRT13 | VSIG10L | 0.843737 | 7 | 0 | 7 |
| KRT13 | TGM3 | 0.84002 | 12 | 0 | 12 |
| KRT13 | ZNF185 | 0.829525 | 11 | 0 | 11 |
| KRT13 | CSTB | 0.826697 | 12 | 0 | 11 |
| KRT13 | MPP7 | 0.824762 | 6 | 0 | 6 |
| KRT13 | SPINK7 | 0.823896 | 8 | 0 | 7 |
| KRT13 | IL1RN | 0.8226 | 13 | 0 | 13 |
| KRT13 | MUC15 | 0.822062 | 7 | 0 | 7 |
| KRT13 | SPINK5 | 0.821966 | 13 | 0 | 11 |
| KRT13 | CAPN14 | 0.821087 | 7 | 0 | 7 |
| KRT13 | A2ML1 | 0.818817 | 8 | 0 | 7 |
| KRT13 | PPL | 0.817774 | 13 | 0 | 11 |
For details and further investigation, click here
