| Full name: syntaxin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 6809 | HGNC ID: HGNC:11438 | Ensembl Gene: ENSG00000166900 | OMIM ID: 600876 |
| Drug and gene relationship at DGIdb | |||
Expression of STX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX3 | 6809 | 209238_at | -0.0657 | 0.9181 | |
| GSE20347 | STX3 | 6809 | 209238_at | -0.0905 | 0.6592 | |
| GSE23400 | STX3 | 6809 | 209238_at | -0.0165 | 0.7717 | |
| GSE26886 | STX3 | 6809 | 209238_at | -0.2491 | 0.2419 | |
| GSE29001 | STX3 | 6809 | 209238_at | -0.4715 | 0.0045 | |
| GSE38129 | STX3 | 6809 | 209238_at | 0.0427 | 0.7983 | |
| GSE45670 | STX3 | 6809 | 209238_at | -0.0669 | 0.6414 | |
| GSE53622 | STX3 | 6809 | 27805 | -0.1528 | 0.0848 | |
| GSE53624 | STX3 | 6809 | 27805 | -0.1620 | 0.0844 | |
| GSE63941 | STX3 | 6809 | 209238_at | 0.1546 | 0.8446 | |
| GSE77861 | STX3 | 6809 | 209238_at | 0.2470 | 0.2926 | |
| GSE97050 | STX3 | 6809 | A_23_P139143 | 0.2830 | 0.4458 | |
| SRP007169 | STX3 | 6809 | RNAseq | -0.9032 | 0.0199 | |
| SRP008496 | STX3 | 6809 | RNAseq | -0.7676 | 0.0011 | |
| SRP064894 | STX3 | 6809 | RNAseq | -0.3579 | 0.0257 | |
| SRP133303 | STX3 | 6809 | RNAseq | 0.0002 | 0.9992 | |
| SRP159526 | STX3 | 6809 | RNAseq | -0.1073 | 0.6756 | |
| SRP193095 | STX3 | 6809 | RNAseq | -0.2470 | 0.2347 | |
| SRP219564 | STX3 | 6809 | RNAseq | -0.1893 | 0.6813 | |
| TCGA | STX3 | 6809 | RNAseq | -0.2120 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX3 | 6809 | 1 | 5 | 24 | |
| GSE20123 | STX3 | 6809 | 1 | 5 | 24 | |
| GSE43470 | STX3 | 6809 | 2 | 5 | 36 | |
| GSE46452 | STX3 | 6809 | 9 | 4 | 46 | |
| GSE47630 | STX3 | 6809 | 3 | 8 | 29 | |
| GSE54993 | STX3 | 6809 | 3 | 0 | 67 | |
| GSE54994 | STX3 | 6809 | 5 | 6 | 42 | |
| GSE60625 | STX3 | 6809 | 0 | 3 | 8 | |
| GSE74703 | STX3 | 6809 | 2 | 3 | 31 | |
| GSE74704 | STX3 | 6809 | 1 | 4 | 15 | |
| TCGA | STX3 | 6809 | 13 | 11 | 72 |
Total number of gains: 40; Total number of losses: 54; Total Number of normals: 394.
Somatic mutations of STX3:
Generating mutation plots.
Highly correlated genes for STX3:
Showing top 20/259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX3 | RNFT1 | 0.807023 | 3 | 0 | 3 |
| STX3 | ZNF217 | 0.802956 | 3 | 0 | 3 |
| STX3 | ATP11B | 0.766162 | 3 | 0 | 3 |
| STX3 | SLC12A6 | 0.756782 | 3 | 0 | 3 |
| STX3 | JAG1 | 0.754165 | 3 | 0 | 3 |
| STX3 | C12orf66 | 0.750964 | 3 | 0 | 3 |
| STX3 | DTD1 | 0.733044 | 3 | 0 | 3 |
| STX3 | PLEKHM1 | 0.724439 | 3 | 0 | 3 |
| STX3 | RBKS | 0.720307 | 3 | 0 | 3 |
| STX3 | CRYBG3 | 0.716019 | 3 | 0 | 3 |
| STX3 | NPAS2 | 0.709967 | 4 | 0 | 3 |
| STX3 | WSB2 | 0.702861 | 3 | 0 | 3 |
| STX3 | VRK3 | 0.702515 | 3 | 0 | 3 |
| STX3 | ZNF267 | 0.699494 | 3 | 0 | 3 |
| STX3 | UFL1 | 0.698399 | 3 | 0 | 3 |
| STX3 | HEATR5B | 0.694382 | 3 | 0 | 3 |
| STX3 | GTF3C1 | 0.694175 | 4 | 0 | 3 |
| STX3 | CYP2C19 | 0.691262 | 3 | 0 | 3 |
| STX3 | PPFIBP2 | 0.687872 | 4 | 0 | 3 |
| STX3 | QRICH1 | 0.687368 | 3 | 0 | 3 |
For details and further investigation, click here
