| Full name: FERM domain containing 4B | Alias Symbol: KIAA1013|GRSP1 | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 23150 | HGNC ID: HGNC:24886 | Ensembl Gene: ENSG00000114541 | OMIM ID: 617467 |
| Drug and gene relationship at DGIdb | |||
Expression of FRMD4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRMD4B | 23150 | 213056_at | -0.9837 | 0.3817 | |
| GSE20347 | FRMD4B | 23150 | 213056_at | -2.0334 | 0.0000 | |
| GSE23400 | FRMD4B | 23150 | 213056_at | -1.3972 | 0.0000 | |
| GSE26886 | FRMD4B | 23150 | 213056_at | -2.3533 | 0.0000 | |
| GSE29001 | FRMD4B | 23150 | 213056_at | -1.4847 | 0.0000 | |
| GSE38129 | FRMD4B | 23150 | 213056_at | -1.3644 | 0.0001 | |
| GSE45670 | FRMD4B | 23150 | 213056_at | -0.5570 | 0.0398 | |
| GSE53622 | FRMD4B | 23150 | 85189 | -1.1263 | 0.0000 | |
| GSE53624 | FRMD4B | 23150 | 85189 | -1.6056 | 0.0000 | |
| GSE63941 | FRMD4B | 23150 | 213056_at | 3.4090 | 0.0003 | |
| GSE77861 | FRMD4B | 23150 | 213056_at | -1.6161 | 0.0005 | |
| GSE97050 | FRMD4B | 23150 | A_33_P3446495 | -0.3215 | 0.5506 | |
| SRP007169 | FRMD4B | 23150 | RNAseq | -2.8586 | 0.0000 | |
| SRP008496 | FRMD4B | 23150 | RNAseq | -2.2716 | 0.0000 | |
| SRP064894 | FRMD4B | 23150 | RNAseq | -2.0153 | 0.0000 | |
| SRP133303 | FRMD4B | 23150 | RNAseq | -1.4535 | 0.0000 | |
| SRP159526 | FRMD4B | 23150 | RNAseq | -1.7666 | 0.0000 | |
| SRP193095 | FRMD4B | 23150 | RNAseq | -1.4651 | 0.0000 | |
| SRP219564 | FRMD4B | 23150 | RNAseq | -1.9379 | 0.0039 | |
| TCGA | FRMD4B | 23150 | RNAseq | 0.0093 | 0.9105 |
Upregulated datasets: 1; Downregulated datasets: 15.
Survival by FRMD4B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRMD4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMD4B | 23150 | 1 | 19 | 10 | |
| GSE20123 | FRMD4B | 23150 | 1 | 19 | 10 | |
| GSE43470 | FRMD4B | 23150 | 0 | 20 | 23 | |
| GSE46452 | FRMD4B | 23150 | 2 | 17 | 40 | |
| GSE47630 | FRMD4B | 23150 | 1 | 23 | 16 | |
| GSE54993 | FRMD4B | 23150 | 5 | 3 | 62 | |
| GSE54994 | FRMD4B | 23150 | 1 | 33 | 19 | |
| GSE60625 | FRMD4B | 23150 | 3 | 1 | 7 | |
| GSE74703 | FRMD4B | 23150 | 0 | 16 | 20 | |
| GSE74704 | FRMD4B | 23150 | 1 | 13 | 6 | |
| TCGA | FRMD4B | 23150 | 0 | 79 | 17 |
Total number of gains: 15; Total number of losses: 243; Total Number of normals: 230.
Somatic mutations of FRMD4B:
Generating mutation plots.
Highly correlated genes for FRMD4B:
Showing top 20/1563 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMD4B | PDCD6IP | 0.853128 | 11 | 0 | 11 |
| FRMD4B | RAB10 | 0.82656 | 6 | 0 | 6 |
| FRMD4B | TJP1 | 0.819381 | 11 | 0 | 11 |
| FRMD4B | SFTA2 | 0.818041 | 4 | 0 | 4 |
| FRMD4B | CDS1 | 0.817503 | 11 | 0 | 11 |
| FRMD4B | SNX24 | 0.817399 | 9 | 0 | 9 |
| FRMD4B | ACPP | 0.815621 | 10 | 0 | 10 |
| FRMD4B | CAST | 0.813283 | 11 | 0 | 11 |
| FRMD4B | C1orf116 | 0.811244 | 11 | 0 | 11 |
| FRMD4B | TMEM154 | 0.807883 | 6 | 0 | 6 |
| FRMD4B | TMOD3 | 0.807428 | 11 | 0 | 10 |
| FRMD4B | TAB3 | 0.806616 | 7 | 0 | 7 |
| FRMD4B | SERPINB1 | 0.80621 | 11 | 0 | 11 |
| FRMD4B | CLIC3 | 0.805858 | 9 | 0 | 8 |
| FRMD4B | ZNF185 | 0.80542 | 10 | 0 | 10 |
| FRMD4B | CWH43 | 0.805214 | 10 | 0 | 10 |
| FRMD4B | CES2 | 0.804447 | 8 | 0 | 8 |
| FRMD4B | RANBP9 | 0.80433 | 11 | 0 | 11 |
| FRMD4B | PADI1 | 0.803015 | 9 | 0 | 9 |
| FRMD4B | VPS4B | 0.802989 | 11 | 0 | 11 |
For details and further investigation, click here
