| Full name: chromosome 16 open reading frame 54 | Alias Symbol: FLJ35681 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 283897 | HGNC ID: HGNC:26649 | Ensembl Gene: ENSG00000185905 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C16orf54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C16orf54 | 283897 | 1559584_a_at | 0.0528 | 0.9846 | |
| GSE26886 | C16orf54 | 283897 | 1559584_a_at | 0.1115 | 0.8393 | |
| GSE45670 | C16orf54 | 283897 | 1559584_a_at | -0.8886 | 0.1061 | |
| GSE53622 | C16orf54 | 283897 | 658 | -0.7297 | 0.0000 | |
| GSE53624 | C16orf54 | 283897 | 658 | -0.7422 | 0.0001 | |
| GSE63941 | C16orf54 | 283897 | 1559584_a_at | 0.2752 | 0.8167 | |
| GSE77861 | C16orf54 | 283897 | 1559584_a_at | -0.0231 | 0.7609 | |
| GSE97050 | C16orf54 | 283897 | A_33_P3227443 | 0.3167 | 0.2096 | |
| SRP007169 | C16orf54 | 283897 | RNAseq | -0.0521 | 0.9451 | |
| SRP064894 | C16orf54 | 283897 | RNAseq | 0.0631 | 0.8117 | |
| SRP133303 | C16orf54 | 283897 | RNAseq | -0.3890 | 0.0124 | |
| SRP159526 | C16orf54 | 283897 | RNAseq | -1.3339 | 0.0908 | |
| SRP193095 | C16orf54 | 283897 | RNAseq | 0.3535 | 0.0485 | |
| SRP219564 | C16orf54 | 283897 | RNAseq | 0.4826 | 0.2306 | |
| TCGA | C16orf54 | 283897 | RNAseq | -0.4934 | 0.0800 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C16orf54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C16orf54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C16orf54 | 283897 | 5 | 5 | 20 | |
| GSE20123 | C16orf54 | 283897 | 5 | 4 | 21 | |
| GSE43470 | C16orf54 | 283897 | 3 | 3 | 37 | |
| GSE46452 | C16orf54 | 283897 | 38 | 1 | 20 | |
| GSE47630 | C16orf54 | 283897 | 11 | 7 | 22 | |
| GSE54993 | C16orf54 | 283897 | 3 | 5 | 62 | |
| GSE54994 | C16orf54 | 283897 | 5 | 9 | 39 | |
| GSE60625 | C16orf54 | 283897 | 4 | 0 | 7 | |
| GSE74703 | C16orf54 | 283897 | 3 | 2 | 31 | |
| GSE74704 | C16orf54 | 283897 | 3 | 2 | 15 | |
| TCGA | C16orf54 | 283897 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of C16orf54:
Generating mutation plots.
Highly correlated genes for C16orf54:
Showing top 20/470 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C16orf54 | PIK3CG | 0.834191 | 5 | 0 | 5 |
| C16orf54 | IRF8 | 0.825023 | 6 | 0 | 6 |
| C16orf54 | GIMAP5 | 0.82077 | 3 | 0 | 3 |
| C16orf54 | CD1D | 0.80269 | 3 | 0 | 3 |
| C16orf54 | GPR65 | 0.799509 | 6 | 0 | 6 |
| C16orf54 | CD226 | 0.797642 | 4 | 0 | 4 |
| C16orf54 | IKZF1 | 0.795014 | 5 | 0 | 5 |
| C16orf54 | PHACTR1 | 0.787948 | 4 | 0 | 4 |
| C16orf54 | GZMK | 0.787121 | 4 | 0 | 4 |
| C16orf54 | P2RY13 | 0.786002 | 5 | 0 | 5 |
| C16orf54 | ARHGAP9 | 0.778896 | 6 | 0 | 6 |
| C16orf54 | GIMAP4 | 0.777653 | 6 | 0 | 6 |
| C16orf54 | ITK | 0.773432 | 6 | 0 | 6 |
| C16orf54 | CD53 | 0.77232 | 4 | 0 | 3 |
| C16orf54 | GRAP2 | 0.76934 | 3 | 0 | 3 |
| C16orf54 | PVRIG | 0.768627 | 4 | 0 | 4 |
| C16orf54 | NCKAP1L | 0.768243 | 5 | 0 | 5 |
| C16orf54 | CD48 | 0.764546 | 5 | 0 | 4 |
| C16orf54 | CSF2RA | 0.761117 | 3 | 0 | 3 |
| C16orf54 | KLRB1 | 0.758118 | 6 | 0 | 6 |
For details and further investigation, click here
