| Full name: chromosome 17 open reading frame 50 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 146853 | HGNC ID: HGNC:29581 | Ensembl Gene: ENSG00000270806 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C17orf50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C17orf50 | 146853 | 237929_at | -0.2280 | 0.3107 | |
| GSE26886 | C17orf50 | 146853 | 237929_at | 0.0130 | 0.9379 | |
| GSE45670 | C17orf50 | 146853 | 237929_at | -0.1708 | 0.0707 | |
| GSE53622 | C17orf50 | 146853 | 19768 | 0.1772 | 0.0758 | |
| GSE53624 | C17orf50 | 146853 | 19768 | 0.3063 | 0.0000 | |
| GSE63941 | C17orf50 | 146853 | 237929_at | 0.1231 | 0.4456 | |
| GSE77861 | C17orf50 | 146853 | 237929_at | -0.1334 | 0.5274 | |
| TCGA | C17orf50 | 146853 | RNAseq | -0.0629 | 0.9307 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C17orf50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C17orf50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C17orf50 | 146853 | 5 | 1 | 24 | |
| GSE20123 | C17orf50 | 146853 | 5 | 1 | 24 | |
| GSE43470 | C17orf50 | 146853 | 1 | 2 | 40 | |
| GSE46452 | C17orf50 | 146853 | 34 | 0 | 25 | |
| GSE47630 | C17orf50 | 146853 | 7 | 1 | 32 | |
| GSE54993 | C17orf50 | 146853 | 3 | 3 | 64 | |
| GSE54994 | C17orf50 | 146853 | 8 | 6 | 39 | |
| GSE60625 | C17orf50 | 146853 | 4 | 0 | 7 | |
| GSE74703 | C17orf50 | 146853 | 1 | 1 | 34 | |
| GSE74704 | C17orf50 | 146853 | 3 | 1 | 16 | |
| TCGA | C17orf50 | 146853 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of C17orf50:
Generating mutation plots.
Highly correlated genes for C17orf50:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C17orf50 | CTIF | 0.661795 | 3 | 0 | 3 |
| C17orf50 | FSHB | 0.661339 | 5 | 0 | 5 |
| C17orf50 | NKAPL | 0.654389 | 3 | 0 | 3 |
| C17orf50 | TTLL9 | 0.649907 | 3 | 0 | 3 |
| C17orf50 | RPL34-AS1 | 0.643187 | 4 | 0 | 3 |
| C17orf50 | VENTX | 0.628302 | 4 | 0 | 3 |
| C17orf50 | LINC00870 | 0.611668 | 3 | 0 | 3 |
| C17orf50 | CRADD | 0.611164 | 3 | 0 | 3 |
| C17orf50 | PHYHIP | 0.610422 | 3 | 0 | 3 |
| C17orf50 | SEMA4A | 0.599218 | 3 | 0 | 3 |
| C17orf50 | PGLYRP1 | 0.597901 | 4 | 0 | 3 |
| C17orf50 | HDAC5 | 0.591371 | 3 | 0 | 3 |
| C17orf50 | DGCR10 | 0.588265 | 3 | 0 | 3 |
| C17orf50 | HOXA-AS2 | 0.58657 | 3 | 0 | 3 |
| C17orf50 | PROP1 | 0.581418 | 4 | 0 | 3 |
| C17orf50 | ADH6 | 0.580877 | 5 | 0 | 4 |
| C17orf50 | OPTC | 0.580729 | 4 | 0 | 3 |
| C17orf50 | ZNF853 | 0.568752 | 4 | 0 | 3 |
| C17orf50 | RTN4RL2 | 0.566862 | 3 | 0 | 3 |
| C17orf50 | TBATA | 0.564475 | 4 | 0 | 3 |
For details and further investigation, click here
