| Full name: follicle stimulating hormone subunit beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p14.1 | ||
| Entrez ID: 2488 | HGNC ID: HGNC:3964 | Ensembl Gene: ENSG00000131808 | OMIM ID: 136530 |
| Drug and gene relationship at DGIdb | |||
FSHB involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway | |
| hsa04913 | Ovarian steroidogenesis |
Expression of FSHB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FSHB | 2488 | 214489_at | -0.1754 | 0.4057 | |
| GSE20347 | FSHB | 2488 | 214489_at | -0.0689 | 0.3458 | |
| GSE23400 | FSHB | 2488 | 214489_at | -0.0799 | 0.0041 | |
| GSE26886 | FSHB | 2488 | 214489_at | -0.0382 | 0.7518 | |
| GSE29001 | FSHB | 2488 | 214489_at | -0.1987 | 0.0749 | |
| GSE38129 | FSHB | 2488 | 214489_at | -0.1719 | 0.0076 | |
| GSE45670 | FSHB | 2488 | 214489_at | -0.0734 | 0.4651 | |
| GSE53622 | FSHB | 2488 | 60103 | 0.3867 | 0.0039 | |
| GSE53624 | FSHB | 2488 | 60103 | 0.0077 | 0.9643 | |
| GSE63941 | FSHB | 2488 | 214489_at | 0.2305 | 0.0950 | |
| GSE77861 | FSHB | 2488 | 214489_at | -0.0694 | 0.6671 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FSHB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FSHB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FSHB | 2488 | 1 | 9 | 20 | |
| GSE20123 | FSHB | 2488 | 1 | 8 | 21 | |
| GSE43470 | FSHB | 2488 | 2 | 4 | 37 | |
| GSE46452 | FSHB | 2488 | 8 | 5 | 46 | |
| GSE47630 | FSHB | 2488 | 3 | 10 | 27 | |
| GSE54993 | FSHB | 2488 | 3 | 0 | 67 | |
| GSE54994 | FSHB | 2488 | 5 | 10 | 38 | |
| GSE60625 | FSHB | 2488 | 0 | 0 | 11 | |
| GSE74703 | FSHB | 2488 | 2 | 2 | 32 | |
| GSE74704 | FSHB | 2488 | 0 | 8 | 12 | |
| TCGA | FSHB | 2488 | 11 | 25 | 60 |
Total number of gains: 36; Total number of losses: 81; Total Number of normals: 371.
Somatic mutations of FSHB:
Generating mutation plots.
Highly correlated genes for FSHB:
Showing top 20/544 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FSHB | LINC00544 | 0.814203 | 3 | 0 | 3 |
| FSHB | GSX1 | 0.697299 | 3 | 0 | 3 |
| FSHB | STX1B | 0.692858 | 4 | 0 | 3 |
| FSHB | FMN2 | 0.68945 | 3 | 0 | 3 |
| FSHB | SEMA3B | 0.678335 | 4 | 0 | 4 |
| FSHB | TCAP | 0.668223 | 4 | 0 | 3 |
| FSHB | GDF2 | 0.663875 | 5 | 0 | 4 |
| FSHB | C17orf50 | 0.661339 | 5 | 0 | 5 |
| FSHB | C10orf90 | 0.656747 | 3 | 0 | 3 |
| FSHB | CHST13 | 0.653578 | 4 | 0 | 3 |
| FSHB | KSR1 | 0.651846 | 3 | 0 | 3 |
| FSHB | LINC00334 | 0.650262 | 3 | 0 | 3 |
| FSHB | CCIN | 0.647749 | 6 | 0 | 5 |
| FSHB | ZGLP1 | 0.644889 | 4 | 0 | 3 |
| FSHB | EPB42 | 0.642828 | 5 | 0 | 3 |
| FSHB | CT62 | 0.640556 | 4 | 0 | 3 |
| FSHB | CHST8 | 0.639205 | 6 | 0 | 5 |
| FSHB | LRFN2 | 0.638816 | 3 | 0 | 3 |
| FSHB | GAL3ST1 | 0.638338 | 4 | 0 | 3 |
| FSHB | ZNF671 | 0.637339 | 5 | 0 | 4 |
For details and further investigation, click here
