DGCR10

 

Full name: DiGeorge syndrome critical region gene 10 Alias Symbol: DGS-B
Type: non-coding RNA Cytoband: 22q11.21
Entrez ID: 26222 HGNC ID: HGNC:17864 Ensembl Gene: ENSG00000273164 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of DGCR10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DGCR10 26222 1557451_at 0.0564 0.8200
GSE26886 DGCR10 26222 1557451_at 0.0179 0.8971
GSE45670 DGCR10 26222 1557451_at 0.0333 0.7479
GSE53622 DGCR10 26222 14880 0.2057 0.0413
GSE53624 DGCR10 26222 14880 0.1595 0.1052
GSE63941 DGCR10 26222 1557451_at 0.1672 0.2042
GSE77861 DGCR10 26222 1557451_at -0.0946 0.4064
TCGA DGCR10 26222 RNAseq 1.5088 0.0257

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DGCR10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DGCR10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DGCR10 26222 4 8 18
GSE20123 DGCR10 26222 4 8 18
GSE43470 DGCR10 26222 5 7 31
GSE46452 DGCR10 26222 32 2 25
GSE47630 DGCR10 26222 8 5 27
GSE54993 DGCR10 26222 3 6 61
GSE54994 DGCR10 26222 12 7 34
GSE60625 DGCR10 26222 5 0 6
GSE74703 DGCR10 26222 5 5 26
GSE74704 DGCR10 26222 2 5 13

Total number of gains: 80; Total number of losses: 53; Total Number of normals: 259.  

 

Somatic mutations of DGCR10:

 

Generating mutation plots.

 

Highly correlated genes for DGCR10:

 

Showing top 20/184 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DGCR10CHRNA40.718382303
DGCR10PHOX2A0.684816303
DGCR10OPRD10.675896303
DGCR10CPNE70.675882505
DGCR10SYNGAP10.670976404
DGCR10NYX0.653889403
DGCR10RARA0.647412303
DGCR10SLC12A10.646808303
DGCR10CACNG40.646661303
DGCR10ADAD20.639378303
DGCR10GALNT90.63081303
DGCR10FSHB0.629476303
DGCR10PKLR0.625739404
DGCR10IGH0.625461303
DGCR10LTK0.622255404
DGCR10CACNB10.621606303
DGCR10ADAM80.621541303
DGCR10LRFN40.620898504
DGCR10OR1J40.618829303
DGCR10HGFAC0.617922303

For details and further investigation, click here