| Full name: sciellin | Alias Symbol: FLJ21667|MGC22531 | ||
| Type: protein-coding gene | Cytoband: 13q22.3 | ||
| Entrez ID: 8796 | HGNC ID: HGNC:10573 | Ensembl Gene: ENSG00000136155 | OMIM ID: 604112 |
| Drug and gene relationship at DGIdb | |||
Expression of SCEL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCEL | 8796 | 206884_s_at | -4.5069 | 0.1004 | |
| GSE20347 | SCEL | 8796 | 206884_s_at | -5.1905 | 0.0000 | |
| GSE23400 | SCEL | 8796 | 206884_s_at | -4.4157 | 0.0000 | |
| GSE26886 | SCEL | 8796 | 206884_s_at | -7.7433 | 0.0000 | |
| GSE29001 | SCEL | 8796 | 206884_s_at | -4.4861 | 0.0000 | |
| GSE38129 | SCEL | 8796 | 206884_s_at | -3.7230 | 0.0000 | |
| GSE45670 | SCEL | 8796 | 206884_s_at | -1.5650 | 0.0132 | |
| GSE53622 | SCEL | 8796 | 90508 | -3.8401 | 0.0000 | |
| GSE53624 | SCEL | 8796 | 90508 | -4.7027 | 0.0000 | |
| GSE63941 | SCEL | 8796 | 206884_s_at | 2.7107 | 0.1630 | |
| GSE77861 | SCEL | 8796 | 206884_s_at | -4.0709 | 0.0088 | |
| GSE97050 | SCEL | 8796 | A_23_P500000 | -1.9079 | 0.1466 | |
| SRP007169 | SCEL | 8796 | RNAseq | -6.2803 | 0.0000 | |
| SRP008496 | SCEL | 8796 | RNAseq | -6.4512 | 0.0000 | |
| SRP064894 | SCEL | 8796 | RNAseq | -5.4124 | 0.0000 | |
| SRP133303 | SCEL | 8796 | RNAseq | -4.2258 | 0.0000 | |
| SRP159526 | SCEL | 8796 | RNAseq | -6.2546 | 0.0000 | |
| SRP219564 | SCEL | 8796 | RNAseq | -5.0855 | 0.0003 | |
| TCGA | SCEL | 8796 | RNAseq | 0.6074 | 0.1640 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by SCEL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCEL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCEL | 8796 | 4 | 11 | 15 | |
| GSE20123 | SCEL | 8796 | 4 | 10 | 16 | |
| GSE43470 | SCEL | 8796 | 4 | 11 | 28 | |
| GSE46452 | SCEL | 8796 | 0 | 32 | 27 | |
| GSE47630 | SCEL | 8796 | 3 | 27 | 10 | |
| GSE54993 | SCEL | 8796 | 11 | 3 | 56 | |
| GSE54994 | SCEL | 8796 | 3 | 14 | 36 | |
| GSE60625 | SCEL | 8796 | 0 | 3 | 8 | |
| GSE74703 | SCEL | 8796 | 3 | 9 | 24 | |
| GSE74704 | SCEL | 8796 | 2 | 9 | 9 | |
| TCGA | SCEL | 8796 | 13 | 33 | 50 |
Total number of gains: 47; Total number of losses: 162; Total Number of normals: 279.
Somatic mutations of SCEL:
Generating mutation plots.
Highly correlated genes for SCEL:
Showing top 20/1263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCEL | SPINK5 | 0.944041 | 12 | 0 | 12 |
| SCEL | SPINK7 | 0.923176 | 8 | 0 | 8 |
| SCEL | VSIG10L | 0.922573 | 7 | 0 | 7 |
| SCEL | TMPRSS11B | 0.917873 | 8 | 0 | 8 |
| SCEL | CYSRT1 | 0.917437 | 7 | 0 | 7 |
| SCEL | TMPRSS11E | 0.916733 | 12 | 0 | 12 |
| SCEL | CRNN | 0.913179 | 12 | 0 | 12 |
| SCEL | TGM3 | 0.907193 | 12 | 0 | 12 |
| SCEL | KLK13 | 0.906287 | 12 | 0 | 12 |
| SCEL | RHCG | 0.89888 | 12 | 0 | 12 |
| SCEL | CLIC3 | 0.898406 | 10 | 0 | 10 |
| SCEL | NCR1 | 0.897884 | 3 | 0 | 3 |
| SCEL | EMP1 | 0.897597 | 12 | 0 | 12 |
| SCEL | PRSS27 | 0.895596 | 9 | 0 | 9 |
| SCEL | PPL | 0.895565 | 13 | 0 | 12 |
| SCEL | NCCRP1 | 0.894318 | 4 | 0 | 4 |
| SCEL | CAPN14 | 0.894246 | 7 | 0 | 7 |
| SCEL | A2ML1 | 0.894111 | 8 | 0 | 8 |
| SCEL | CNFN | 0.892388 | 8 | 0 | 8 |
| SCEL | SLURP1 | 0.889034 | 13 | 0 | 12 |
For details and further investigation, click here
