| Full name: C1D nuclear receptor corepressor | Alias Symbol: SUNCOR|SUN-CoR|LRP1|Rrp47 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 10438 | HGNC ID: HGNC:29911 | Ensembl Gene: ENSG00000197223 | OMIM ID: 606997 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of C1D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1D | 10438 | 200056_s_at | 0.2137 | 0.6240 | |
| GSE20347 | C1D | 10438 | 200056_s_at | 0.5096 | 0.0064 | |
| GSE23400 | C1D | 10438 | 200056_s_at | 0.4499 | 0.0000 | |
| GSE26886 | C1D | 10438 | 200056_s_at | 0.1475 | 0.6255 | |
| GSE29001 | C1D | 10438 | 200056_s_at | 0.4163 | 0.3772 | |
| GSE38129 | C1D | 10438 | 200056_s_at | 0.5884 | 0.0001 | |
| GSE45670 | C1D | 10438 | 200056_s_at | 0.3342 | 0.0482 | |
| GSE53622 | C1D | 10438 | 41317 | 0.4893 | 0.0000 | |
| GSE53624 | C1D | 10438 | 41317 | 0.4710 | 0.0001 | |
| GSE63941 | C1D | 10438 | 200056_s_at | -0.1475 | 0.7214 | |
| GSE77861 | C1D | 10438 | 200056_s_at | 0.5544 | 0.1798 | |
| GSE97050 | C1D | 10438 | A_23_P56590 | 0.5002 | 0.1399 | |
| SRP007169 | C1D | 10438 | RNAseq | 0.0489 | 0.9041 | |
| SRP008496 | C1D | 10438 | RNAseq | -0.0783 | 0.7335 | |
| SRP064894 | C1D | 10438 | RNAseq | 0.2543 | 0.1191 | |
| SRP133303 | C1D | 10438 | RNAseq | 0.8524 | 0.0000 | |
| SRP159526 | C1D | 10438 | RNAseq | 0.5100 | 0.0340 | |
| SRP193095 | C1D | 10438 | RNAseq | 0.1878 | 0.2434 | |
| SRP219564 | C1D | 10438 | RNAseq | 0.1516 | 0.4649 | |
| TCGA | C1D | 10438 | RNAseq | 0.1021 | 0.0866 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C1D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1D | 10438 | 11 | 0 | 19 | |
| GSE20123 | C1D | 10438 | 11 | 0 | 19 | |
| GSE43470 | C1D | 10438 | 6 | 0 | 37 | |
| GSE46452 | C1D | 10438 | 2 | 3 | 54 | |
| GSE47630 | C1D | 10438 | 7 | 0 | 33 | |
| GSE54993 | C1D | 10438 | 0 | 6 | 64 | |
| GSE54994 | C1D | 10438 | 12 | 0 | 41 | |
| GSE60625 | C1D | 10438 | 0 | 3 | 8 | |
| GSE74703 | C1D | 10438 | 6 | 0 | 30 | |
| GSE74704 | C1D | 10438 | 9 | 0 | 11 | |
| TCGA | C1D | 10438 | 36 | 2 | 58 |
Total number of gains: 100; Total number of losses: 14; Total Number of normals: 374.
Somatic mutations of C1D:
Generating mutation plots.
Highly correlated genes for C1D:
Showing top 20/1262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1D | LRIG3 | 0.814736 | 3 | 0 | 3 |
| C1D | LRRC58 | 0.754254 | 3 | 0 | 3 |
| C1D | ARFGEF2 | 0.7492 | 3 | 0 | 3 |
| C1D | ZBTB34 | 0.744276 | 4 | 0 | 4 |
| C1D | ABCB10 | 0.728803 | 4 | 0 | 4 |
| C1D | ITGB8 | 0.718103 | 3 | 0 | 3 |
| C1D | HERPUD2 | 0.706242 | 3 | 0 | 3 |
| C1D | ATP6V1A | 0.704643 | 3 | 0 | 3 |
| C1D | PDE8A | 0.699162 | 4 | 0 | 3 |
| C1D | AZIN1 | 0.699073 | 3 | 0 | 3 |
| C1D | MAPK9 | 0.698343 | 4 | 0 | 3 |
| C1D | DHX36 | 0.696437 | 5 | 0 | 5 |
| C1D | LDLR | 0.691475 | 3 | 0 | 3 |
| C1D | NFKB1 | 0.69137 | 4 | 0 | 4 |
| C1D | SLC7A6OS | 0.687659 | 3 | 0 | 3 |
| C1D | RPL41 | 0.682294 | 4 | 0 | 4 |
| C1D | SLC25A24 | 0.680916 | 9 | 0 | 7 |
| C1D | BUD31 | 0.678678 | 6 | 0 | 6 |
| C1D | PRDX3 | 0.678537 | 7 | 0 | 7 |
| C1D | SRSF1 | 0.678234 | 3 | 0 | 3 |
For details and further investigation, click here
