| Full name: chromosome 1 open reading frame 198 | Alias Symbol: FLJ14525|MGC10710|FLJ16283|DKFZp667D152|FLJ38847 | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 84886 | HGNC ID: HGNC:25900 | Ensembl Gene: ENSG00000119280 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of C1orf198:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf198 | 84886 | 223063_at | 0.3469 | 0.3211 | |
| GSE26886 | C1orf198 | 84886 | 223063_at | 0.4801 | 0.0322 | |
| GSE45670 | C1orf198 | 84886 | 223063_at | -0.1141 | 0.5438 | |
| GSE53622 | C1orf198 | 84886 | 62029 | 0.3367 | 0.0000 | |
| GSE53624 | C1orf198 | 84886 | 62029 | 0.5000 | 0.0000 | |
| GSE63941 | C1orf198 | 84886 | 223063_at | -1.2039 | 0.0076 | |
| GSE77861 | C1orf198 | 84886 | 223063_at | 0.6010 | 0.0052 | |
| GSE97050 | C1orf198 | 84886 | A_32_P42574 | -0.1859 | 0.7484 | |
| SRP007169 | C1orf198 | 84886 | RNAseq | 0.2790 | 0.4270 | |
| SRP008496 | C1orf198 | 84886 | RNAseq | 0.5674 | 0.0028 | |
| SRP064894 | C1orf198 | 84886 | RNAseq | 0.6622 | 0.0000 | |
| SRP133303 | C1orf198 | 84886 | RNAseq | 0.5144 | 0.0073 | |
| SRP159526 | C1orf198 | 84886 | RNAseq | 0.6557 | 0.0069 | |
| SRP193095 | C1orf198 | 84886 | RNAseq | 0.5718 | 0.0000 | |
| SRP219564 | C1orf198 | 84886 | RNAseq | 0.0888 | 0.8688 | |
| TCGA | C1orf198 | 84886 | RNAseq | 0.0129 | 0.8065 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C1orf198 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf198:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf198 | 84886 | 11 | 0 | 19 | |
| GSE20123 | C1orf198 | 84886 | 11 | 0 | 19 | |
| GSE43470 | C1orf198 | 84886 | 8 | 1 | 34 | |
| GSE46452 | C1orf198 | 84886 | 4 | 2 | 53 | |
| GSE47630 | C1orf198 | 84886 | 15 | 0 | 25 | |
| GSE54993 | C1orf198 | 84886 | 0 | 6 | 64 | |
| GSE54994 | C1orf198 | 84886 | 17 | 0 | 36 | |
| GSE60625 | C1orf198 | 84886 | 0 | 0 | 11 | |
| GSE74703 | C1orf198 | 84886 | 8 | 1 | 27 | |
| GSE74704 | C1orf198 | 84886 | 5 | 0 | 15 | |
| TCGA | C1orf198 | 84886 | 45 | 3 | 48 |
Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.
Somatic mutations of C1orf198:
Generating mutation plots.
Highly correlated genes for C1orf198:
Showing top 20/911 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf198 | KIF16B | 0.790773 | 3 | 0 | 3 |
| C1orf198 | FRY | 0.771088 | 3 | 0 | 3 |
| C1orf198 | EEF2 | 0.760493 | 3 | 0 | 3 |
| C1orf198 | PRRC2C | 0.750764 | 3 | 0 | 3 |
| C1orf198 | FOXF1 | 0.748416 | 4 | 0 | 4 |
| C1orf198 | KIAA0753 | 0.747302 | 3 | 0 | 3 |
| C1orf198 | ULK1 | 0.744734 | 4 | 0 | 4 |
| C1orf198 | WFDC1 | 0.74157 | 4 | 0 | 4 |
| C1orf198 | RAB34 | 0.736642 | 3 | 0 | 3 |
| C1orf198 | SLC16A4 | 0.734277 | 3 | 0 | 3 |
| C1orf198 | GNB5 | 0.733792 | 3 | 0 | 3 |
| C1orf198 | GNG11 | 0.732641 | 4 | 0 | 4 |
| C1orf198 | FBXO7 | 0.731143 | 3 | 0 | 3 |
| C1orf198 | BMPR1A | 0.727182 | 4 | 0 | 4 |
| C1orf198 | FGF12 | 0.723471 | 3 | 0 | 3 |
| C1orf198 | RGS5 | 0.722435 | 3 | 0 | 3 |
| C1orf198 | NCOR2 | 0.719253 | 4 | 0 | 3 |
| C1orf198 | DIAPH2 | 0.718835 | 3 | 0 | 3 |
| C1orf198 | TBL2 | 0.717381 | 3 | 0 | 3 |
| C1orf198 | SNTB2 | 0.715573 | 3 | 0 | 3 |
For details and further investigation, click here
