| Full name: diaphanous related formin 2 | Alias Symbol: POF|DIA|POF2|DIA2 | ||
| Type: protein-coding gene | Cytoband: Xq21.33 | ||
| Entrez ID: 1730 | HGNC ID: HGNC:2877 | Ensembl Gene: ENSG00000147202 | OMIM ID: 300108 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
DIAPH2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04810 | Regulation of actin cytoskeleton |
Expression of DIAPH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DIAPH2 | 1730 | 205726_at | -0.8587 | 0.2005 | |
| GSE20347 | DIAPH2 | 1730 | 205726_at | -0.3325 | 0.2776 | |
| GSE23400 | DIAPH2 | 1730 | 205726_at | -0.1926 | 0.3186 | |
| GSE26886 | DIAPH2 | 1730 | 205726_at | 0.6748 | 0.2029 | |
| GSE29001 | DIAPH2 | 1730 | 205726_at | -0.5972 | 0.1815 | |
| GSE38129 | DIAPH2 | 1730 | 205726_at | -0.6380 | 0.0511 | |
| GSE45670 | DIAPH2 | 1730 | 205726_at | -0.9599 | 0.0245 | |
| GSE53622 | DIAPH2 | 1730 | 64779 | -0.5777 | 0.0000 | |
| GSE53624 | DIAPH2 | 1730 | 64779 | -0.4577 | 0.0000 | |
| GSE63941 | DIAPH2 | 1730 | 205603_s_at | -0.2227 | 0.8812 | |
| GSE77861 | DIAPH2 | 1730 | 205726_at | 0.5692 | 0.0759 | |
| GSE97050 | DIAPH2 | 1730 | A_23_P85004 | -0.2857 | 0.4552 | |
| SRP007169 | DIAPH2 | 1730 | RNAseq | -0.2664 | 0.5204 | |
| SRP008496 | DIAPH2 | 1730 | RNAseq | 0.3544 | 0.2387 | |
| SRP064894 | DIAPH2 | 1730 | RNAseq | -0.1457 | 0.4716 | |
| SRP133303 | DIAPH2 | 1730 | RNAseq | -0.5703 | 0.0278 | |
| SRP159526 | DIAPH2 | 1730 | RNAseq | 0.6988 | 0.1895 | |
| SRP193095 | DIAPH2 | 1730 | RNAseq | 0.0944 | 0.5618 | |
| SRP219564 | DIAPH2 | 1730 | RNAseq | -0.4197 | 0.4161 | |
| TCGA | DIAPH2 | 1730 | RNAseq | -0.1966 | 0.0576 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DIAPH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DIAPH2:
No record found for this gene.
Somatic mutations of DIAPH2:
Generating mutation plots.
Highly correlated genes for DIAPH2:
Showing top 20/630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DIAPH2 | ATP10A | 0.807677 | 3 | 0 | 3 |
| DIAPH2 | DCHS1 | 0.780839 | 4 | 0 | 4 |
| DIAPH2 | VSTM4 | 0.775977 | 3 | 0 | 3 |
| DIAPH2 | FNIP2 | 0.771273 | 3 | 0 | 3 |
| DIAPH2 | CNTLN | 0.763178 | 3 | 0 | 3 |
| DIAPH2 | CYP4V2 | 0.760582 | 3 | 0 | 3 |
| DIAPH2 | DAPK1 | 0.750893 | 4 | 0 | 4 |
| DIAPH2 | PDK2 | 0.746223 | 3 | 0 | 3 |
| DIAPH2 | PRKG2 | 0.738901 | 3 | 0 | 3 |
| DIAPH2 | FKBP5 | 0.738785 | 3 | 0 | 3 |
| DIAPH2 | NUDT16 | 0.727683 | 3 | 0 | 3 |
| DIAPH2 | THAP8 | 0.725636 | 3 | 0 | 3 |
| DIAPH2 | ADARB1 | 0.724423 | 5 | 0 | 5 |
| DIAPH2 | SLC35F1 | 0.720843 | 3 | 0 | 3 |
| DIAPH2 | FILIP1 | 0.71971 | 4 | 0 | 3 |
| DIAPH2 | C1orf198 | 0.718835 | 3 | 0 | 3 |
| DIAPH2 | FGF12 | 0.716973 | 3 | 0 | 3 |
| DIAPH2 | DDIT3 | 0.7136 | 4 | 0 | 4 |
| DIAPH2 | SNX25 | 0.713343 | 3 | 0 | 3 |
| DIAPH2 | HINT2 | 0.70967 | 3 | 0 | 3 |
For details and further investigation, click here
