| Full name: syntrophin beta 2 | Alias Symbol: EST25263|SNT3 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 6645 | HGNC ID: HGNC:11169 | Ensembl Gene: ENSG00000168807 | OMIM ID: 600027 |
| Drug and gene relationship at DGIdb | |||
Expression of SNTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNTB2 | 6645 | 226685_at | 0.1580 | 0.8089 | |
| GSE20347 | SNTB2 | 6645 | 205315_s_at | 0.4146 | 0.0018 | |
| GSE23400 | SNTB2 | 6645 | 205315_s_at | 0.1616 | 0.0503 | |
| GSE26886 | SNTB2 | 6645 | 226685_at | -0.2855 | 0.2769 | |
| GSE29001 | SNTB2 | 6645 | 205315_s_at | 0.1301 | 0.5905 | |
| GSE38129 | SNTB2 | 6645 | 205315_s_at | 0.0993 | 0.5728 | |
| GSE45670 | SNTB2 | 6645 | 226685_at | -0.4196 | 0.0113 | |
| GSE53622 | SNTB2 | 6645 | 106633 | -0.1848 | 0.0106 | |
| GSE53624 | SNTB2 | 6645 | 23550 | 0.0514 | 0.5325 | |
| GSE63941 | SNTB2 | 6645 | 226685_at | -1.4169 | 0.0090 | |
| GSE77861 | SNTB2 | 6645 | 226685_at | 0.4023 | 0.2508 | |
| GSE97050 | SNTB2 | 6645 | A_33_P3331906 | -0.0007 | 0.9975 | |
| SRP007169 | SNTB2 | 6645 | RNAseq | 0.9689 | 0.0193 | |
| SRP008496 | SNTB2 | 6645 | RNAseq | 0.9981 | 0.0000 | |
| SRP064894 | SNTB2 | 6645 | RNAseq | -0.2096 | 0.3838 | |
| SRP133303 | SNTB2 | 6645 | RNAseq | 0.0936 | 0.4371 | |
| SRP159526 | SNTB2 | 6645 | RNAseq | 0.0552 | 0.7367 | |
| SRP193095 | SNTB2 | 6645 | RNAseq | 0.2882 | 0.0364 | |
| SRP219564 | SNTB2 | 6645 | RNAseq | -0.2635 | 0.5215 | |
| TCGA | SNTB2 | 6645 | RNAseq | 0.0118 | 0.8132 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SNTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNTB2 | 6645 | 8 | 1 | 21 | |
| GSE20123 | SNTB2 | 6645 | 8 | 1 | 21 | |
| GSE43470 | SNTB2 | 6645 | 2 | 8 | 33 | |
| GSE46452 | SNTB2 | 6645 | 38 | 1 | 20 | |
| GSE47630 | SNTB2 | 6645 | 11 | 8 | 21 | |
| GSE54993 | SNTB2 | 6645 | 2 | 4 | 64 | |
| GSE54994 | SNTB2 | 6645 | 8 | 10 | 35 | |
| GSE60625 | SNTB2 | 6645 | 4 | 0 | 7 | |
| GSE74703 | SNTB2 | 6645 | 2 | 5 | 29 | |
| GSE74704 | SNTB2 | 6645 | 4 | 0 | 16 | |
| TCGA | SNTB2 | 6645 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 50; Total Number of normals: 322.
Somatic mutations of SNTB2:
Generating mutation plots.
Highly correlated genes for SNTB2:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNTB2 | KBTBD6 | 0.810978 | 3 | 0 | 3 |
| SNTB2 | GLA | 0.771607 | 3 | 0 | 3 |
| SNTB2 | ELF4 | 0.768945 | 3 | 0 | 3 |
| SNTB2 | PTGFRN | 0.763693 | 3 | 0 | 3 |
| SNTB2 | GATAD1 | 0.751273 | 3 | 0 | 3 |
| SNTB2 | ZFP90 | 0.748749 | 3 | 0 | 3 |
| SNTB2 | CERS2 | 0.742888 | 3 | 0 | 3 |
| SNTB2 | PAK1 | 0.739696 | 3 | 0 | 3 |
| SNTB2 | POC5 | 0.736555 | 4 | 0 | 3 |
| SNTB2 | SEC22C | 0.732806 | 6 | 0 | 6 |
| SNTB2 | SCAMP1 | 0.728466 | 3 | 0 | 3 |
| SNTB2 | LACTB | 0.724361 | 3 | 0 | 3 |
| SNTB2 | CTDSPL | 0.716609 | 3 | 0 | 3 |
| SNTB2 | C1orf198 | 0.715573 | 3 | 0 | 3 |
| SNTB2 | HEXB | 0.715081 | 5 | 0 | 4 |
| SNTB2 | TTC7B | 0.714056 | 3 | 0 | 3 |
| SNTB2 | SGTB | 0.712268 | 5 | 0 | 4 |
| SNTB2 | DPYSL2 | 0.712227 | 5 | 0 | 5 |
| SNTB2 | CHST3 | 0.710964 | 4 | 0 | 4 |
| SNTB2 | ANPEP | 0.708847 | 4 | 0 | 4 |
For details and further investigation, click here
